Search Results - "Martínez‐Arias, Laura"
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Fibrosis in Chronic Kidney Disease: Pathogenesis and Consequences
Published in International journal of molecular sciences (02-01-2021)“…Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix as a response to different types of tissue injuries, which leads…”
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2
Variants in cardiac GATA genes associated with bicuspid aortic valve
Published in European journal of clinical investigation (01-12-2018)“…Background Bicuspid aortic valve (BAV) is a heterogeneous and still not fully understood condition, with diverse genetic aetiology and associated phenotypes…”
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3
Experimental Models to Study Diabetes Mellitus and Its Complications: Limitations and New Opportunities
Published in International journal of molecular sciences (01-06-2023)“…Preclinical biomedical models are a fundamental tool to improve the knowledge and management of diseases, particularly in diabetes mellitus (DM) since,…”
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4
Barley-ß-glucans reduce systemic inflammation, renal injury and aortic calcification through ADAM17 and neutral-sphingomyelinase2 inhibition
Published in Scientific reports (28-11-2019)“…In chronic kidney disease (CKD), hyperphosphatemia-induced inflammation aggravates vascular calcification (VC) by increasing vascular smooth muscle cell (VSMC)…”
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Vitamin D Treatment Prevents Uremia-Induced Reductions in Aortic microRNA-145 Attenuating Osteogenic Differentiation despite Hyperphosphatemia
Published in Nutrients (22-06-2022)“…In chronic kidney disease, systemic inflammation and high serum phosphate (P) promote the de-differentiation of vascular smooth muscle cells (VSMC) to…”
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Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure
Published in Nutrients (01-04-2023)“…Drugs providing antihypertensive and protective cardiovascular actions are of clinical interest in controlling cardiovascular events and slowing the…”
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Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia
Published in Aging and disease (01-10-2018)“…In mammalians, advancing age is associated with sarcopenia, the progressive and involuntary loss of muscle mass and strength. Hyperphosphatemia is an…”
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8
Redox Metabolism and Vascular Calcification in Chronic Kidney Disease
Published in Biomolecules (Basel, Switzerland) (01-09-2023)“…Vascular calcification (VC) is a common complication in patients with chronic kidney disease which increases their mortality. Although oxidative stress is…”
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Role of the RANK/RANKL/OPG and Wnt/β-Catenin Systems in CKD Bone and Cardiovascular Disorders
Published in Calcified tissue international (01-04-2021)“…In the course of chronic kidney disease (CKD), alterations in the bone-vascular axis augment the risk of bone loss, fractures, vascular and soft tissue…”
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10
MicroRNAs 29b, 133b, and 211 Regulate Vascular Smooth Muscle Calcification Mediated by High Phosphorus
Published in Journal of the American Society of Nephrology (01-03-2016)“…Vascular calcification is a frequent cause of morbidity and mortality in patients with CKD and the general population. The common association between vascular…”
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11
High-serum phosphate and parathyroid hormone distinctly regulate bone loss and vascular calcification in experimental chronic kidney disease
Published in Nephrology, dialysis, transplantation (01-06-2019)“…Abstract Background In chronic kidney disease (CKD), increases in serum phosphate and parathyroid hormone (PTH) aggravate vascular calcification (VC) and bone…”
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Effects of calcitriol and paricalcitol on renal fibrosis in CKD
Published in Nephrology, dialysis, transplantation (26-04-2021)“…In chronic kidney disease, the activation of the renin-angiotensin-aldosterone system (RAAS) and renal inflammation stimulates renal fibrosis and the…”
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13
Regulation of miR-29b and miR-30c by vitamin D receptor activators contributes to attenuate uraemia-induced cardiac fibrosis
Published in Nephrology, dialysis, transplantation (01-11-2017)“…Uraemic cardiomyopathy, a process mainly associated with increased myocardial fibrosis, is the leading cause of death in chronic kidney disease patients and…”
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Contribution of phosphorus and PTH to the development of cardiac hypertrophy and fibrosis in an experimental model of chronic renal failure
Published in Nefrología (01-11-2021)“…BACKGROUND AND OBJECTIVEAdequate serum phosphorus levels in patients with chronic kidney disease is essential for their clinical management. However, the…”
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Contribution of phosphorus and PTH to the development of cardiac hypertrophy and fibrosis in an experimental model of chronic renal failure
Published in Nefrología (01-11-2021)“…Adequate serum phosphorus levels in patients with chronic kidney disease is essential for their clinical management. However, the control of hyperphosphatemia…”
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Descripción taxonómica y funcional de un ensamblaje de epífitas vasculares en la Cordillera Occidental Colombiana
Published in Caldasia (01-05-2024)“…Las epífitas vasculares son componentes taxonómicos y funcionales relevantes en los ecosistemas húmedos, por lo que explorar su diversidad cobra relevancia en…”
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Contribución de fósforo y PTH al desarrollo de hipertrofia y fibrosis cardíaca en un modelo experimental de insuficiencia renal crónica
Published in Nefrología (01-11-2021)“…Mantener niveles adecuados de fósforo sérico en el paciente con enfermedad renal crónica es fundamental para su correcto manejo clínico. Sin embargo resulta…”
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18
Panorama actual del aneurisma cerebral
Published in Universidad Médica Pinareña (01-03-2018)“…El aneurisma cerebral es una patología frecuente dentro de las malformaciones arteriovenosas y se caracteriza por la dilatación de las paredes arteriales de la…”
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The receptor activator of nuclear factor κΒ ligand receptor leucine-rich repeat-containing G-protein-coupled receptor 4 contributes to parathyroid hormone-induced vascular calcification
Published in Nephrology, dialysis, transplantation (29-03-2021)“…Abstract Background In chronic kidney disease, serum phosphorus (P) elevations stimulate parathyroid hormone (PTH) production, causing severe alterations in…”
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20
Panorama actual del aneurisma cerebral
Published in Universidad Médica Pinareña (01-03-2018)“…El aneurisma cerebral es una patología frecuente dentro de las malformaciones arteriovenosas y se caracteriza por la dilatación de las paredes arteriales de la…”
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