Search Results - "Martínez‐Alonso, Marta"
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A Novel Near‐IR Absorbing Ruthenium(II) Complex as Photosensitizer for Photodynamic Therapy and its Cetuximab Bioconjugates
Published in Chembiochem : a European journal of chemical biology (01-08-2023)“…A novel Ru(II) cyclometalated photosensitizer (PS), Ru‐NH2, for photodynamic therapy (PDT) of formula [Ru(appy)(bphen)2]PF6 (where…”
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Hybrid Hydroxyapatite-Metal Complex Materials Derived from Amino Acids and Nucleobases
Published in Molecules (Basel, Switzerland) (20-09-2024)“…Calcium phosphates (CaPs) and their substituted derivatives encompass a large number of compounds with a vast presence in nature that have aroused a great…”
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Highly Stable and Efficient Light-Emitting Electrochemical Cells Based on Cationic Iridium Complexes Bearing Arylazole Ancillary Ligands
Published in Inorganic chemistry (05-09-2017)“…A series of bis-cyclometalated iridium(III) complexes of general formula [Ir(ppy)2(N∧N)][PF6] (ppy– = 2-phenylpyridinate; N∧N =…”
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Bombesin-Targeted Delivery of β‑Carboline-Based Ir(III) and Ru(II) Photosensitizers for a Selective Photodynamic Therapy of Prostate Cancer
Published in Inorganic chemistry (14-10-2024)“…Despite advances in Ir(III) and Ru(II) photosensitizers (PSs), their lack of selectivity for cancer cells has hindered their use in photodynamic therapy…”
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Strong Influence of Ancillary Ligands Containing Benzothiazole or Benzimidazole Rings on Cytotoxicity and Photoactivation of Ru(II) Arene Complexes
Published in Inorganic chemistry (19-11-2018)“…A new family of neutral ruthenium(II) arene complexes of the type [Ru(η6-arene)X(κ2-O,N-L)] (η6-arene = p-cym, bz; X = Cl–, SCN–; HL1 =…”
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Derivation of Structure–Activity Relationships from the Anticancer Properties of Ruthenium(II) Arene Complexes with 2‑Aryldiazole Ligands
Published in Inorganic chemistry (20-10-2014)“…The ligands 2-pyridin-2-yl-1H-benzimidazole (HL1), 1-methyl-2-pyridin-2-ylbenzimidazole (HL2), and 2-(1H-imidazol-2-yl)pyridine (HL3) and the proligand…”
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Strong Influence of the Ancillary Ligand over the Photodynamic Anticancer Properties of Neutral Biscyclometalated IrIII Complexes Bearing 2‐Benzoazole‐Phenolates
Published in Chemistry : a European journal (27-11-2018)“…In this paper, the synthesis, comprehensive characterization and biological and photocatalytic properties of two series of neutral IrIII biscyclometalated…”
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Selective Photooxidation of Sulfides Catalyzed by Bis-cyclometalated Ir III Photosensitizers Bearing 2,2'-Dipyridylamine-Based Ligands
Published in Chemistry : a European journal (25-07-2018)“…A new family of heteroleptic bis-cyclometalated Ir complexes with formula [Ir(CN^ ) (NN^ )]Cl (CN^ =2-phenylpyridinate and NN^ =2,2'-dipyridylamine or…”
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Anticancer Activity and DNA Binding of a Bifunctional Ru(II) Arene Aqua-Complex with the 2,4-Diamino-6-(2-pyridyl)-1,3,5-triazine Ligand
Published in Inorganic chemistry (03-09-2013)“…The synthesis and full characterization of the new aqua-complex [(η6 -p-cymene)Ru(OH2)(κ2 -N,N-2-pydaT)](BF4)2, [2](BF 4 ) 2 , and the nucleobase derivative…”
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10
Ruthenium polypyridyl complex-containing bioconjugates
Published in Coordination chemistry reviews (01-05-2021)“…[Display omitted] •Bioconjugation improves some of the features of Ru(II) polypyridyl complexes•The intrinsic properties of the complexes are not usually…”
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Selective Photooxidation of Sulfides Catalyzed by Bis‐cyclometalated IrIII Photosensitizers Bearing 2,2′‐Dipyridylamine‐Based Ligands
Published in Chemistry : a European journal (25-07-2018)“…A new family of heteroleptic bis‐cyclometalated IrIII complexes with formula [Ir(CN^ )2(NN^ )]Cl (CN^ =2‐phenylpyridinate and NN^ =2,2′‐dipyridylamine or…”
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Monomer–Dimer Divergent Behavior toward DNA in a Half-Sandwich Ruthenium(II) Aqua Complex. Antiproliferative Biphasic Activity
Published in Organometallics (12-01-2015)“…The complex [(η6-p-cymene)Ru(OH2)(κ2-N,N-HL1)](OTf)2 (HL1 = 2-pyridin-2-yl-1H-benzimidazole), [2c](OTf) 2 , undergoes easy deprotonation of the N–H group at…”
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Thiabendazole-based Rh(III) and Ir(III) biscyclometallated complexes with mitochondria-targeted anticancer activity and metal-sensitive photodynamic activity
Published in European journal of medicinal chemistry (05-09-2018)“…Two pairs of Rh(III) and Ir(III) biscyclometallated complexes with thiabendazole (L1), named [Ir-a]Cl and [Rh-a]Cl, and N-benzyl-thiabendazole (L2), named…”
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Insights into the anticancer photodynamic activity of Ir(III) and Ru(II) polypyridyl complexes bearing β-carboline ligands
Published in European journal of medicinal chemistry (05-10-2024)“…Ir(III) and Ru(II) polypyridyl complexes are promising photosensitizers (PSs) for photodynamic therapy (PDT) due to their outstanding photophysical properties…”
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Phototoxicity of cyclometallated Ir(III) complexes bearing a thio-bis-benzimidazole ligand, and its monodentate analogue, as potential PDT photosensitisers in cancer cell killing
Published in Journal of biological inorganic chemistry (2024)“…Two novel cyclometallated iridium(III) complexes have been prepared with one bidentate or two monodentate imidazole-based ligands, 1 and 2 , respectively. The…”
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Experimental and theoretical characterization of the strong effects on DNA stability caused by half-sandwich Ru(II) and Ir(III) bearing thiabendazole complexes
Published in Journal of biological inorganic chemistry (01-12-2020)“…The synthesis and characterization of two half-sandwich complexes of Ru(II) and Ir(III) with thiabendazole as ancillary ligand and their DNA binding ability…”
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Targets, Mechanisms and Cytotoxicity of Half-Sandwich Ir(III) Complexes Are Modulated by Structural Modifications on the Benzazole Ancillary Ligand
Published in Cancers (24-12-2022)“…Cancers are driven by multiple genetic mutations but evolve to evade treatments targeting specific mutations. Nonetheless, cancers cannot evade a treatment…”
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Strong Influence of the Ancillary Ligand over the Photodynamic Anticancer Properties of Neutral Biscyclometalated Ir III Complexes Bearing 2-Benzoazole-Phenolates
Published in Chemistry : a European journal (27-11-2018)“…In this paper, the synthesis, comprehensive characterization and biological and photocatalytic properties of two series of neutral Ir biscyclometalated…”
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Hybrid aramids, Ir(III)-functionalized aromatic polyamides
Published in European polymer journal (01-10-2017)“…This work describes the synthesis and characterization of aromatic polyamides with iridium biscyclometalated units, together with the study of their physical…”
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Analysis of Ion Pairing in Solid State and Solution in p‑Cymene Ruthenium Complexes
Published in Inorganic chemistry (05-10-2020)“…The importance of ion pairing in different fields of chemistry is widely recognized. In this work, we have synthesized a set of cationic p-cymene ruthenium…”
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