Search Results - "Martín de la Vega, C"

Therapeutic window for melanoma treatment provided by selective effects of the proteasome on Bcl-2 proteins by Wolter, K G, Verhaegen, M, Fernández, Y, Nikolovska-Coleska, Z, Riblett, M, de la Vega, C Martin, Wang, S, Soengas, M S

“…Melanoma cells depend on sustained proteasomal function for survival. However, bortezomib, the first proteasome inhibitor in clinical use, is not sufficient to…”
Get full text

Possible mechanisms involved in the down-regulation of translation during transient global ischaemia in the rat brain by Martín de la Vega, C, Burda, J, Nemethova, M, Quevedo, C, Alcázar, A, Martín, M E, Danielisova, V, Fando, J L, Salinas, M

“…The striking correlation between neuronal vulnerability and down-regulation of translation suggests that this cellular process plays a critical part in the…”
Get full text

Resistance of Initiation Factor 2 (eIF-2α) Kinases to Staurosporine: An Approach for Assaying the Kinases in Crude Extracts by Martı́n de la Vega, C, Garcı́a, A, Martı́n, M.E, Alcázar, A, Marin, O, Quevedo, C, Salinas, M

“…We studied the effect of staurosporine on two well characterised mammalian eIF-2α kinases, the heme-regulated translational inhibitor (HRI), and…”
Get full text

Ischemia-induced inhibition of the initiation factor 2alpha phosphatase activity in the rat brain by Martín de la Vega, C, Burda, J, Salinas, M

“…Rats were subjected to the standard four-vessel occlusion model of brain transient ischemia for 30 min. Following different recirculation periods, the level of…”
Get full text

Calcium mobilization by ryanodine promotes the phosphorylation of initiation factor 2alpha subunit and inhibits protein synthesis in cultured neurons by Alcázar, A, Martín de la Vega, C, Bazán, E, Fando, J L, Salinas, M

“…Protein synthesis plays an important role in the viability and function of the cell. There is evidence indicating that Ca2+ may be a physiological regulator of…”
Get full text

Lauryl gallate inhibits the activity of protein tyrosine kinase c-Src purified from human platelets by Palacios, C, Cespón, C, Martín De La Vega, C, Roy, G, Serrano, A, Salinas, M, González-Porqué, P

“…The inhibitory effect of gallic acid (3,4,5-trihydroxybenzoic acid), and its ester derivatives methyl, propyl, octyl and lauryl has been tested on the tyrosine…”
Get more information

Resistance of Initiation Factor 2 (eIF-2α) Kinases to Staurosporine by Martı́n de la Vega, C, Garcı́a, A, Martı́n, M.E, Alcázar, A, Marin, O, Quevedo, C, Salinas, M

Get full text