Search Results - "Martín Perez-Santos"

Colon carcinoma treatment using bispecific anti-GITR/CTLA-4 antibodies: a patent evaluation of WO2018091739 by Millán-Pérez Peña, Lourdes, Martin, Perez-Santos, Herrera-Camacho, Irma, Bandala, Cindy, Anaya-Ruiz, Maricruz

“…: GITR is a receptor that increases the activation of T lymphocytes against tumor cells. There is a great need to discover and develop new therapies focused on…”
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Alternative Splicing in Breast Cancer and the Potential Development of Therapeutic Tools by Martínez-Montiel, Nancy, Anaya-Ruiz, Maricruz, Pérez-Santos, Martín, Martínez-Contreras, Rebeca D

“…Alternative splicing is a key molecular mechanism now considered as a hallmark of cancer that has been associated with the expression of distinct isoforms…”
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Estrogens as a Possible Therapeutic Strategy for the Management of Neuroinflammation and Neuroprotection in COVID-19 by Cindy Bandala, Noemí Cárdenas-Rodríguez, Samuel Reyes-Long, Alfredo Cortés-Algara, Itzel Jatziri Contreras-García, Teresita Rocío Cruz-Hernández, Alfonso Alfaro-Rodriguez, José Luis Cortes-Altamirano, Martín Perez-Santos, Maricruz Anaya-Ruiz, Eleazar Lara-Padilla

“…The Coronavirus disease 2019 (COVID-19) affects several tissues, including the central and peripheral nervous system. It has also been related to signs and…”
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Nanostructured Systems in Advanced Drug Targeting for the Cancer Treatment: Recent Patents by Anaya-Ruiz, Maricruz, Bandala, Cindy, Landeta, Gerardo, Martínez-Morales, Patricia, Zumaquero-Rios, Jose L, Sarracent-Pérez, Jorge, Pérez-Santos, Martín

“…Cancer is one of the leading causes of death in the world and it is necessary to develop new strategies for its treatment because most therapies have limited…”
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miR-485 acts as a tumor suppressor by inhibiting cell growth and migration in breast carcinoma T47D cells by Anaya-Ruiz, Maricruz, Bandala, Cindy, Perez-Santos, Jose Luis Martin

“…MicroRNAs (miRNAs) are small, non-coding RNAs (18-25 nucleotides) that post-transcriptionally modulate gene expression by negatively regulating the stability…”
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Neurophysiological Mechanisms Related to Pain Management in Bone Tumors by Romero-Morelos, Pablo, Ruvalcaba-Paredes, Erika, Garciadiego-Cázares, David, Pérez-Santos, Martín, Reyes-Long, Samuel, Alfaro-Rodriguez, Alfonso, Salcedo, Mauricio, Mancilla-Ramírez, Javier, Bandala, Cindy

“…Background: Primary and metastatic bone tumor incidence has increased in the previous years. Pain is a common symptom and is one of the most important related…”
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miR-153 silencing induces apoptosis in the MDA-MB-231 breast cancer cell line by Anaya-Ruiz, Maricruz, Cebada, Jorge, Delgado-López, Guadalupe, Sánchez-Vázquez, María Luisa, Pérez-Santos, José Luis Martín

“…MicroRNAs (miRNAs) are small, non-coding RNAs (18-25 nucleotides) that post-transcriptionally modulate gene expression by negatively regulating the stability…”
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Contribution of Latin American Countries to Cancer Research and Patent Generation: Recent Patents by Perez-Santos, Martin, Anaya-Ruiz, Maricruz, Bandala, Cindy

“…Data mining publications and patent data can provide decision support for scientists, inventors and industry in the field of cancer research. The main…”
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Bursera copallifera Extracts Have Cytotoxic and Migration-Inhibitory Effects in Breast Cancer Cell Lines by Domínguez, Fabiola, Maycotte, Paola, Acosta-Casique, Adilene, Rodríguez-Rodríguez, Sofía, Moreno, Diego A., Ferreres, Federico, Flores-Alonso, Juan Carlos, Delgado-López, María Guadalupe, Pérez-Santos, Martín, Anaya-Ruiz, Maricruz

“…Plants from the Bursera genus are widely distributed in the tropical dry forests of Mexico. In traditional medicine, extracts from different species of Bursera…”
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Effect of botulinum toxin A on proliferation and apoptosis in the T47D breast cancer cell line by Bandala, Cindy, Perez-Santos, Jose Luis Martin, Lara-Padilla, Eleazar, Delgado Lopez, Guadalupe, Anaya-Ruiz, Maricruz

“…The present study was performed to assess the activity of the botulinum toxin A on breast cancer cells. The T47D cell line was exposed to diverse…”
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Mexican breast cancer research output, 2003-2012 by Perez-Santos, Jose Luis Martin, Anaya-Ruiz, Maricruz

“…The objetive of this study was to explore a bibliometric approach to quantitatively assess current research trends with regard to breast cancer in Mexico…”
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La inmunización con productos de excreción-secreción de Trichinella spiralis unido al bloqueo de CTLA-4 produce un elevado grado de protección ante un reto con el parásito by Zumaquero-Ríos, José Lino, Pérez-Santos, Martín, Villa-Mancera, Abel, Sarracent-Pérez, Jorge

“…En la búsqueda de una vacuna experimental efectiva contra Trichinella spiralis se han utilizado diferentes estrategias, pero el grado de protección alcanzado…”
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Bispecific anti-PD-1/CTLA-4 antibody for advanced solid tumors by Perez-Santos, Martin

“…PD-1 and CTLA-4 are checkpoint inhibitors of the immune response in cancer, making them the target molecules for the development of therapeutic antibodies…”
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Bispecific anti-OX40/5T4 antibodies for cancer treatment by Perez-Santos, Martin

“…OX40 and 5T4 are molecules that play a role in T-cell expansion and cytoskeleton’s disruption in cancer, respectively. US2019161555 patent describes a…”
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Drug repurposing of adapalene for melanoma treatment by Anaya-Ruiz, Maricruz, Perez-Santos, Martin

“…Cancer drug repurposing is an attractive approach that leads to savings in time and investment. Adapalene, the first medical application of which was for the…”
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Small-molecule inhibitor PD-1/PD-L1 interaction for colorectal cancer treatment by Anaya-Ruiz, Maricruz, Perez-Santos, Martin

“…Inhibition of the PD-1/PD-L1 pathway is a target for the development of new therapies. US10710986 patent describes a small molecule that targets PDL-1/PD-1…”
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Bispecific anti-PD-1/LAG-3 antibodies for treatment of advanced or metastatic solid tumors: a patent evaluation of US2018326054 by Cebada, Jorge, Flores, Amira, Bandala, Cindy, Lizaliturri-Flores, Ian, Villa-Ruano, Nemesio, Perez-Santos, Martin

“…Due to the primary role of PD-1 and LAG-3 in regulating the immune response in tumors, there is a need to develop therapies focused on the inhibition of PD-1…”
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Patenting trends in the pharmaceutical field of Mexican universities by Sanchez-Esgua, Gabriela, Reyes-Alvarez, Juan, Perez-Santos, Martin

“…: pharmaceutical patenting activity in developing countries, including Mexico, is unknown. : determine the activity of pharmaceutical patents by Mexican…”
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Approaches for development of LAG-3 inhibitors and the promise they hold as anticancer agents by Perez-Santos, Martin, Anaya-Ruiz, Maricruz, Villafaña-Diaz, Luis, Sánchez Esgua, Gabriela

“…LAG-3 is considered to be the third point of immunological control in relation to clinical trials that address cancer treatment, only behind PD-1 and CTLA-4,…”
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Innovation Status of Gene Therapy for Breast Cancer by Anaya-Ruiz, Maricruz, Perez-Santos, Martin

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