Search Results - "Martín‐Villa, José Manuel"
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HLA‐G in Mayas from Yucatan: An evolutionary approach
Published in International journal of immunogenetics (01-10-2021)“…HLA‐G allele frequencies were studied in Yucatán (Mexico) Maya Amerindians by a direct exon DNA sequencing technique. It is described that Mayas are probably…”
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2
Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector
Published in PLoS pathogens (01-03-2014)“…Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells…”
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3
HLA-G: Too Much or Too Little? Role in Cancer and Autoimmune Disease
Published in Frontiers in immunology (27-01-2022)“…HLA-G is a non-classical HLA class I molecule with immunomodulatory properties. It was initially described at the maternal-fetal interface, and it was later…”
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HLA-G 3'UTR Polymorphisms Are Linked to Susceptibility and Survival in Spanish Gastric Adenocarcinoma Patients
Published in Frontiers in immunology (07-09-2021)“…HLA-G is a non-classical class I HLA molecule that induces tolerance by acting on receptors of both innate and adaptive immune cells. When overexpressed in…”
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5
Genetic signature detected in T cell receptors from patients with severe COVID-19
Published in iScience (20-10-2023)“…Characterization of host genetic factors contributing to COVID-19 severity promises advances on drug discovery to fight the disease. Most genetic analyses to…”
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TGFB1 polymorphisms and TGF‐β1 plasma levels identify gastric adenocarcinoma patients with lower survival rate and disseminated disease
Published in Journal of cellular and molecular medicine (01-01-2021)“…TGF‐β1 is involved in tumour growth. Four TGFB1 SNPs and TGF‐β1 production by stimulated PBMC were determined in seventy‐eight gastric adenocarcinoma patients…”
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Major histocompatibility complex compement (MHC) Bf alleles show trans species evolution between man and chimpanzee
Published in Scientific reports (04-10-2023)“…HLA and disease studies by using single allele statistics have been fruitless during the last 40 years for explaining association pathogenesis of the…”
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Lack of association between the protein tyrosine phosphatase non-receptor type 22 R263Q and R620W functional genetic variants and endogenous non-anterior uveitis
Published in Molecular vision (20-03-2013)“…Endogenous uveitis is a major cause of visual loss mediated by the immune system. The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene encodes a…”
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Major histocompatibility complex complement (MHC) Bf alleles show trans species evolution between man and chimpanzee
Published in Scientific reports (04-10-2023)“…HLA and disease studies by using single allele statistics have been fruitless during the last 40 years for explaining association pathogenesis of the…”
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10
Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells
Published in The Journal of immunology (1950) (01-05-2015)“…TCR-αβ(+) double-negative (DN; CD4(-)CD8(-)) T cells represent a poorly understood cellular subset suggested to contribute to the pathogenesis of the…”
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The Immune Modulation HLA-G01:01:01 Full Allele Is Associated with Gastric Adenocarcinoma Development
Published in International journal of molecular sciences (01-10-2024)“…The Human Leukocyte Antigen (HLA) system contains a set of genes involved at many levels in the innate and adaptive immune response. Among the non-classical…”
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HLA alleles and haplotypes in Sudanese population and their relationship with Mediterraneans
Published in Scientific reports (27-09-2023)“…The contribution of migrated people from once green Sahara (about 10,000–6000 years bc ) towards Mediterranean area had probably a double effect: both genetic…”
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Complex Interactions between the Human Major Histocompatibility Complex (MHC) and Microbiota: Their Roles in Disease Pathogenesis and Immune System Regulation
Published in Biomedicines (01-08-2024)“…The relationship between microbiota and the immune system is complex and characterized by the ways in which microbiota directs immune function interactions,…”
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Pro‐inflammatory self‐reactive T cells are found within murine TCR‐αβ+CD4−CD8−PD‐1+ cells
Published in European journal of immunology (01-06-2016)“…TCR‐αβ+ double negative (DN) T cells (CD3+TCR‐αβ+CD4−CD8−NK1.1−CD49b−) represent a minor heterogeneous population in healthy humans and mice. These cells have…”
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Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector: e1004022
Published in PLoS pathogens (01-03-2014)“…Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells…”
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16
Mixtec Mexican Amerindians: an HLA Alleles Study for America Peopling, Pharmacogenomics and Transplantation
Published in Immunological investigations (01-11-2014)“…HLA-A, -B and -DRB1 alleles have been studied in a Mixtec Mexican Amerindian population by indirect DNA sequencing. HLA relatedness has been tested by…”
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Specific association of IL17A genetic variants with panuveitis
Published in British journal of ophthalmology (01-04-2015)“…A pathogenic role of Th17 cells in uveitis has become clear in recent years. Therefore, in the present study, we aimed to evaluate the possible influence of…”
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No evidence of association between common autoimmunity STAT4 and IL23R risk polymorphisms and non-anterior uveitis
Published in PloS one (29-11-2013)“…STAT4 and IL23R loci represent common susceptibility genetic factors in autoimmunity. We decided to investigate for the first time the possible role of…”
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HLA in Georgians (Caucasus) and their relationship with Eastern Mediterraneans
Published in Molecular biology reports (01-10-2013)“…HLA-A, -B, -DQB1, and –DRB1 typing has been performed in a sample of Georgian population (South Caucasus). Allele frequencies, neighbour joining and…”
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Gorgan (Turkmen in Iran) HLA genetics: transplantation, pharmacogenomics and anthropology
Published in Immunological investigations (01-01-2015)“…HLA class I and II alleles have been studied in a population from Gorgan (North East Iranian city bordering Turkmenistan). This population is composed of…”
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