Search Results - "Martín‐Hernández, Roberto"
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Sirt1 protects from K‐Ras‐driven lung carcinogenesis
Published in EMBO reports (01-09-2018)“…The NAD + ‐dependent deacetylase SIRT1 can be oncogenic or tumor suppressive depending on the tissue. Little is known about the role of SIRT1 in non‐small cell…”
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Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer
Published in PloS one (03-06-2014)“…Colorectal and pancreatic cancers remain important contributors to cancer mortality burden and, therefore, new therapeutic approaches are urgently needed…”
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Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity
Published in Nature communications (27-09-2022)“…Fasting exerts beneficial effects in mice and humans, including protection from chemotherapy toxicity. To explore the involved mechanisms, we collect blood…”
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Connection between miRNA Mediation and the Bioactive Effects of Broccoli (Brassica oleracea var. italica): Exogenous miRNA Resistance to Food Processing and GI Digestion
Published in Journal of agricultural and food chemistry (18-08-2021)“…Broccoli (Brassica oleracea var. italica) and its bioactive compounds are associated with beneficial health effects, which might be enabled, at least in part,…”
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Modulation of Cholesterol-Related Gene Expression by Dietary Fiber Fractions from Edible Mushrooms
Published in Journal of agricultural and food chemistry (26-08-2015)“…Mushrooms are a source of dietary fiber (DF) with a cholesterol-lowering effect. However, their underlying mechanisms are poorly understood. The effect of…”
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Customized Dietary Intervention Avoids Unintentional Weight Loss and Modulates Circulating miRNAs Footprint in Huntington's Disease
Published in Molecular nutrition & food research (01-12-2018)“…Scope Huntington's disease (HD) is a rare progressive neurodegenerative disorder of genetic origin, with no definitive treatment. Unintentional weight loss…”
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Data mining of nutrigenomics experiments: Identification of a cancer protective gene signature
Published in Journal of functional foods (01-03-2018)“…[Display omitted] •Data mining of publicly available nutrigenomics experiments.•Hierarchical clustering based on gene expression.•Downregulation of genes…”
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Exercise dose affects the circulating microRNA profile in response to acute endurance exercise in male amateur runners
Published in Scandinavian journal of medicine & science in sports (01-10-2020)“…The systemic response to exercise is dose‐dependent and involves a complex gene expression regulation and cross‐talk between tissues. This context ARISES the…”
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Next‐generation sequencing reveals that miR‐16‐5p, miR‐19a‐3p, miR‐451a, and miR‐25‐3p cargo in plasma extracellular vesicles differentiates sedentary young males from athletes
Published in European journal of sport science (01-06-2024)“…A sedentary lifestyle and Olympic participation are contrary risk factors for global mortality and incidence of cancer and cardiovascular disease…”
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Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge
Published in Nutrients (13-06-2019)“…Postprandial lipemia has many physiopathological effects, some of which increase the risk of cardiovascular disease. MicroRNAs (miRNAs) can be found in almost…”
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Plasma Cholesterol-Lowering Activity of Lard Functionalized with Mushroom Extracts Is Independent of Niemann–Pick C1-like 1 Protein and ABC Sterol Transporter Gene Expression in Hypercholesterolemic Mice
Published in Journal of agricultural and food chemistry (02-03-2016)“…Interest in food matrices supplemented with mushrooms as hypocholesterolemic functional foods is increasing. This study was to (i) investigate the…”
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Comparative Transcriptomes of the Body Wall of Wild and Farmed Sea Cucumber Isostichopus badionotus
Published in International journal of molecular sciences (09-04-2021)“…Overfishing of sea cucumber from Yucatan has led to a major population decline. They are being captured as an alternative to traditional species despite a…”
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HRQoL and nutritional well-being dissimilarities between two different online collection methods: Value for digital health implementation
Published in Digital health (01-01-2022)“…Background Online health data collection has gained a reputation over the last years to record and process information about health issues for implementing…”
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3'UTR Polymorphism in ACSL1 Gene Correlates with Expression Levels and Poor Clinical Outcome in Colon Cancer Patients
Published in PloS one (19-12-2016)“…Strong evidence suggests that lipid metabolism (LM) has an essential role in tumor growth to support special energetic and structural requirements of tumor…”
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A Comprehensive In Silico Analysis of the Functional and Structural Impact of Nonsynonymous SNPs in the ABCA1 Transporter Gene
Published in Cholesterol (01-01-2014)“…Disease phenotypes and defects in function can be traced to nonsynonymous single nucleotide polymorphisms (nsSNPs), which are important indicators of action…”
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The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance
Published in Scientific reports (31-05-2018)“…Glycosyltransferase enzyme GCNT3, has been proposed as a biomarker for prognosis in colorectal cancer (CRC). Our study goes in depth into the molecular basis…”
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Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs
Published in European journal of nutrition (01-12-2021)“…Purpose Exosomes are extracellular vesicles secreted by cells, which can transport different molecules, including nucleic acids. Dietary habits may induce gene…”
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Cardiometabolic Health Status, Ethnicity and Health-Related Quality of Life (HRQoL) Disparities in an Adult Population: NutrIMDEA Observational Web-Based Study
Published in International journal of environmental research and public health (03-03-2022)“…Precision public health supported on online tools is increasingly emerging as a potential strategy to achieve health promotion and disease prevention. Our aim…”
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Modulation of miRNA expression in aged rat hippocampus by buttermilk and krill oil
Published in Scientific reports (05-03-2018)“…The increasing incidence of age-induced cognitive decline justifies the search for complementary ways of prevention or delay. We studied the effects of…”
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The transcriptional and mutational landscapes of lipid metabolism-related genes in colon cancer
Published in Oncotarget (19-01-2018)“…Metabolic alterations encountered in tumors are well recognized and considered as a hallmark of cancer. In addition to Warburg Effect, epidemiological and…”
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