Search Results - "Martín‐Broto, J."

Hidradenitis suppurativa secondary to treatment with a gamma secretase inhibitor by Ríos‐Viñuela, E., Hoyas‐Rodríguez, I., Cullen‐Aravena, D., Martín‐Broto, J., Hindi, N., Eraña, I., Requena, L.

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Giant cell tumour of bone: new treatments in development by López-Pousa, A., Broto, J. Martín, Garrido, T., Vázquez, J.

“…Giant cell tumour of bone (GCTB) is a benign osteolytic tumour with three main cellular components: multinucleated osteoclast-like giant cells, mononuclear…”
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SEOM Clinical Guideline of management of soft-tissue sarcoma (2020) by de Juan Ferré, A., Álvarez Álvarez, R., Casado Herráez, A., Cruz Jurado, J., Estival González, A., Martín-Broto, J., Martínez Marín, V., Moreno Vega, A., Sebio García, A., Valverde Morales, C.

“…Soft-tissue sarcomas constitute an uncommon and heterogeneous group of tumors of mesenchymal origin. Diagnosis, treatment, and management should be performed…”
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The paediatric cancer clinical research landscape in Spain: a 13-year multicentre experience of the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP) by Rubio-San-Simón, A., Hladun Alvaro, R., Juan Ribelles, A., Castañeda Heredia, A., Guerra-García, P., Verdú-Amorós, J., Andrés, M., Cañete, A., Rives, S., Pérez-Martínez, A., Mora, J., Patiño-García, A., Lassaleta, A., Llort, A., Ramírez, M., Mata, C., Gallego, S., Martín-Broto, J., Cruz, O., Morales La Madrid, A., Solano, P., Martínez Romera, I., Fernández‑Teijeiro, A., Bautista, F., Moreno, L.

“…Purpose Early phase trials are crucial in developing innovative effective agents for childhood malignancies. We report the activity in early phase paediatric…”
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Phase I trial of sorafenib in combination with ifosfamide in patients with advanced sarcoma: a Spanish group for research on sarcomas (GEIS) study by Martín-Liberal, J., López-Pousa, A., Broto, J. Martín, Cubedo, R., Gallego, O., Brendel, E., Tirado, O. M., del Muro, X. García

“…Summary Background This phase I trial assessed safety, pharmacokinetics (PK), dose limiting toxicity (DLT), maximum tolerated dose and recommended dose (RD) of…”
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Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group by Gronchi, A., Stacchiotti, S., Verderio, P., Ferrari, S., Martin Broto, J., Lopez-Pousa, A., Llombart-Bosch, A., Dei Tos, A.P., Collini, P., Jurado, J.C.r.u.z., De Paoli, A., Donati, D.M., Poveda, A., Quagliuolo, V., Comandone, A., Grignani, G., Morosi, C., Messina, A., De Sanctis, R., Bottelli, S., Palassini, E., Casali, P.G., Picci, P.i.e.r.o.

“…The equivalence of a short full-dose regimen of neoadjuvant CT with anthracycline-ifosfamide compared with standard dosing in localized high-risk soft tissue…”
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Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group by Stacchiotti, S., Gronchi, A., Fossati, P., Akiyama, T., Alapetite, C., Baumann, M., Blay, J.Y., Bolle, S., Boriani, S., Bruzzi, P., Capanna, R., Caraceni, A., Casadei, R., Colia, V., Debus, J., Delaney, T., Desai, A., Dileo, P., Dijkstra, S., Doglietto, F., Flanagan, A., Froelich, S., Gardner, P.A., Gelderblom, H., Gokaslan, Z.L., Haas, R., Heery, C., Hindi, N., Hohenberger, P., Hornicek, F., Imai, R., Jeys, L., Jones, R.L., Kasper, B., Kawai, A., Krengli, M., Leithner, A., Logowska, I., Martin Broto, J., Mazzatenta, D., Morosi, C., Nicolai, P., Norum, O.J., Patel, S., Penel, N., Picci, P., Pilotti, S., Radaelli, S., Ricchini, F., Rutkowski, P., Scheipl, S., Sen, C., Tamborini, E., Thornton, K.A., Timmermann, B., Torri, V., Tunn, P.U., Uhl, M., Yamada, Y., Weber, D.C., Vanel, D., Varga, P.P., Vleggeert-Lankamp, C.L.A., Casali, P.G., Sommer, J.

“…Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until recently, there was no consensus among experts regarding appropriate…”
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Final analysis of the randomized trial on imatinib as an adjuvant in localized gastrointestinal stromal tumors (GIST) from the EORTC Soft Tissue and Bone Sarcoma Group (STBSG), the Australasian Gastro-Intestinal Trials Group (AGITG), UNICANCER, French Sarcoma Group (FSG), Italian Sarcoma Group (ISG), and Spanish Group for Research on Sarcomas (GEIS) by Casali, P.G., Le Cesne, A., Velasco, A.P., Kotasek, D., Rutkowski, P., Hohenberger, P., Fumagalli, E., Judson, I.R., Italiano, A., Gelderblom, H., Penel, N., Hartmann, J.T., Duffaud, F., Goldstein, D., Martin-Broto, J., Gronchi, A., Wardelmann, E., Marréaud, S., Zalcberg, J.R., Litière, S., Blay, J.-Y.

“…In 2004, we started an intergroup randomized trial of adjuvant imatinib versus no further therapy after R0-R1 surgery in localized, high/intermediate-risk…”
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Gemcitabine plus sirolimus for relapsed and progressing osteosarcoma patients after standard chemotherapy: a multicenter, single-arm phase II trial of Spanish Group for Research on Sarcoma (GEIS) by Martin-Broto, J., Redondo, A., Valverde, C., Vaz, M.A., Mora, J., Garcia del Muro, X., Gutierrez, A., Tous, C., Carnero, A., Marcilla, D., Carranza, A., Sancho, P., Martinez-Trufero, J., Diaz-Beveridge, R., Cruz, J., Encinas, V., Taron, M., Moura, D.S., Luna, P., Hindi, N., Lopez-Pousa, A.

“…Patients with relapsed unresectable osteosarcoma represents an unmet need, so active and safe systemic treatments are required. Fas cell surface death receptor…”
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SEOM Clinical Guideline of management of soft-tissue sarcoma (2016) by López-Pousa, A., Martin Broto, J., Martinez Trufero, J., Sevilla, I., Valverde, C., Alvarez, R., Carrasco Alvarez, J. A., Cruz Jurado, J., Hindi, N., Garcia del Muro, X.

“…Soft-tissue sarcomas are uncommon and heterogeneous tumors of mesenchymal origin. A soft-tissue mass that is increasing in size, greater than 5 cm, or located…”
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Prognostic time dependence of deletions affecting codons 557 and/or 558 of KIT gene for relapse-free survival (RFS) in localized GIST: a Spanish Group for Sarcoma Research (GEIS) Study by Martin-Broto, J., Gutierrez, A., Garcia-del-Muro, X., Lopez-Guerrero, J.A., Martinez-Trufero, J., de Sande, L.M., Lainez, N., Maurel, J., De Juan, A., Losa, F., Andres, R., Casado, A., Tejido, P.G., Blanco, R., Carles, J., Bellmunt, J., Gomez-España, A., Ramos, R., Martinez-Serra, J., Llombart-Bosch, A., Poveda, A.

“…To assess whether deletions involving codons 557 and/or 558 (critical deletions) of exon 11 of KIT are relevant in the prognosis of relapse-free survival (RFS)…”
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An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG) by Kasper, B., Baumgarten, C., Garcia, J., Bonvalot, S., Haas, R., Haller, F., Hohenberger, P., Penel, N., Messiou, C., van der Graaf, W.T., Gronchi, A., Bauer, S., Blay, J.Y., van Coevorden, F., Dileo, P., Dürr, H.R., Fiore, M., Grünwald, V., Jones, R., Judson, I., Kettelhack, C., Kopeckova, K., Lazar, A., Lindner, L.H., Martin-Broto, J., Rutkowski, P., Stacchiotti, S., Stoeckle, E., Valverde, C., Verhoef, K., Wardelmann, E., Wartenberg, M.

“…Desmoid-type fibromatosis is a rare and locally aggressive monoclonal, fibroblastic proliferation characterized by a variable and often unpredictable clinical…”
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Follow-up strategies for patients with gastrointestinal stromal tumour treated with or without adjuvant imatinib after surgery by Joensuu, H, Martin-Broto, J, Nishida, T, Reichardt, P, Schöffski, P, Maki, R.G

“…Abstract Background Patients with gastrointestinal stromal tumour (GIST) are often followed up after surgery with longitudinally repeated imaging examinations…”
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1624MO Weekly nab-paclitaxel for progressive or symptomatic desmoid tumors: A multicenter single arm phase II trial from the Spanish Group for Research on Sarcoma (GEIS) by Broto, J. Martin, Hindi, N., Redondo, A., Morales, J.M., Marcilla, D., Valverde, C., Luna, P., Diaz-Beveritge, R., Martinez-Trufero, J., Lopez-Martin, J.A., Martinez, V., Gutierrez, A., Lopez-Pousa, A.

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Systemic treatment in advanced phyllodes tumor of the breast: a multi-institutional European retrospective case-series analyses by Palassini, E., Mir, O., Grignani, G., Vincenzi, B., Gelderblom, H., Sebio, A., Valverde, C., Baldi, G. G., Brunello, A., Cardellino, G. G., Marrari, A., Badalamenti, G., Martin-Broto, J., Ferraresi, V., Libertini, M., Turano, S., Gataa, I., Collini, P., Tos, A. P. Dei, Gennaro, M., Bini, F., Provenzano, S., Vullo, S. Lo, Mariani, L., Le Cesne, A., Casali, P. G.

“…Background We aimed at investigating outcome of systemic treatments in advanced breast PT. Methods All cases of advanced breast PT treated with systemic…”
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Indirect comparisons in cost-effectiveness analysis: are we being naïve? by Martin-Broto, J.

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Is There a Role for Neo-Adjuvant Systemic Treatment in Sts? by Broto, J. Martín

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84INIS THERE A ROLE FOR NEO-ADJUVANT SYSTEMIC TREATMENT IN STS? by Broto, J. Martín

“…Abstract I will try to answer this question after first replying this one: Is there any room for complementary systemic treatment in STS and if so, then are…”
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GEIS-21: a multicentric phase II study of intensive chemotherapy including gemcitabine and docetaxel for the treatment of Ewing sarcoma of children and adults: a report from the Spanish sarcoma group (GEIS) by Mora, J, Castañeda, A, Perez-Jaume, S, Lopez-Pousa, A, Maradiegue, E, Valverde, C, Martin-Broto, J, Garcia del Muro, X, Cruz, O, Cruz, J, Martinez-Trufero, J, Maurel, J, Vaz, M A, de Alava, E, de Torres, C

“…Background: First Spanish trial of Ewing sarcoma (ES) including adults and children with the aim to test the efficacy of Gemcitabine and Docetaxel (G/D) in…”
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Synovial sarcoma: characteristics, challenges and evolving therapeutic strategies by Blay, Jean-Yves, von Mehren, Margaret, Jones, Robin L., Martin-Broto, Javier, Stacchiotti, Silvia, Bauer, Sebastian, Gelderblom, Hans, Orbach, Daniel, Hindi, Nadia, Tos, Angelo Dei, Nathenson, Michael

“…Synovial sarcoma (SS) is a rare and aggressive disease that accounts for 5%-10% of all soft tissue sarcomas. Although it can occur at any age, it typically…”
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