Search Results - "Martín, M. Elena"
-
1
Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses
Published in Pharmaceuticals (Basel, Switzerland) (16-12-2016)“…Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically…”
Get full text
Journal Article Book Review -
2
DNA aptamers targeting Leishmania infantum H3 protein as potential diagnostic tools
Published in Analytica chimica acta (22-04-2020)“…Leishmaniasis is a disease caused by a parasite of the genus Leishmania that affects millions of people worldwide. These parasites are characterized by the…”
Get full text
Journal Article -
3
Conformational Changes of the Alanine Dipeptide in Water–Ethanol Binary Mixtures
Published in Journal of chemical theory and computation (12-04-2016)“…Experimental work developed in the last years has evidenced the capacity of alcohols and polyalcohols to modify the energy landscape of peptides and proteins…”
Get full text
Journal Article -
4
TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models
Published in Molecular therapy (01-08-2018)“…Since Toll-like receptor 4 (TLR4) mediates brain damage after stroke, development of TLR4 antagonists is a promising therapeutic strategy for this disease. Our…”
Get full text
Journal Article -
5
Molecular and Functional Characterization of ssDNA Aptamers that Specifically Bind Leishmania infantum PABP
Published in PloS one (12-10-2015)“…A poly (A)-binding protein from Leishmania infantum (LiPABP) has been recently cloned and characterized in our laboratory. Although this protein shows a very…”
Get full text
Journal Article -
6
Feasibility Study on Measuring the Particulate Matter Level in the Atmosphere by Means of Yagi–Uda-Like Antennas
Published in Sensors (Basel, Switzerland) (05-06-2020)“…In this work, the application of a technique for monitoring changes of the dielectric constant of the atmosphere caused by the presence of pollution is…”
Get full text
Journal Article -
7
How Methylation Modifies the Photophysics of the Native All-trans-Retinal Protonated Schiff Base: A CASPT2/MD Study in Gas Phase and in Methanol
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (22-03-2018)“…A comparison between the free-energy surfaces of the all-trans-retinal protonated Schiff base (RPSB) and its 10-methylated derivative in gas phase and methanol…”
Get full text
Journal Article -
8
Radiofrequency at 2.45 GHz increases toxicity, pro-inflammatory and pre-apoptotic activity caused by black carbon in the RAW 264.7 macrophage cell line
Published in The Science of the total environment (15-04-2021)“…Environmental factors such as air pollution by particles and/or electromagnetic fields (EMFs) are studied as harmful agents for human health. We analyzed…”
Get full text
Journal Article -
9
A Theoretical Study of Solvent Effects on the Structure and UV–vis Spectroscopy of 3‑Hydroxyflavone (3-HF) and Some Simplified Molecular Models
Published in ACS omega (06-06-2023)“…Solvent effects on the UV–vis spectra of 3-hydroxyflavone and other structurally related molecules (3-hydroxychromen-4-one, 3-hydroxy-4-pyrone, and 4-pyrone)…”
Get full text
Journal Article -
10
Potential Therapeutic Use of Aptamers against HAT1 in Lung Cancer
Published in Cancers (30-12-2022)“…Lung cancer is one of the leading causes of death worldwide and the most common of all cancer types. Histone acetyltransferase 1 (HAT1) has attracted…”
Get full text
Journal Article -
11
Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells
Published in Molecular therapy. Nucleic acids (01-01-2016)“…Elevated expression levels of eukaryotic initiation factor 4E (eIF4E) promote cancer development and progression. MAP kinase interacting kinases (MNKs)…”
Get full text
Journal Article -
12
Theoretical Study of Solvent Effects on the Ground and Low-Lying Excited Free Energy Surfaces of a Push–Pull Substituted Azobenzene
Published in The journal of physical chemistry. B (30-10-2014)“…The ground and low-lying excited free energy surfaces of 4-amino-4′-cyano azobenzene, a molecule that has been proposed as building block for chiroptical…”
Get full text
Journal Article -
13
DNA aptamers selectively target Leishmania infantum H2A protein
Published in PloS one (21-10-2013)“…Parasites of the genus Leishmania produce leishmaniasis which affects millions people around the world. Understanding the molecular characteristics of the…”
Get full text
Journal Article -
14
Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis
Published in Frontiers in cellular and infection microbiology (05-04-2018)“…Different members of intracellular protein families are recognized by the immune system of the vertebrate host infected by parasites of the genus . Here, we…”
Get full text
Journal Article -
15
Simultaneous Solvent and Counterion Effects on the Absorption Properties of a Model of the Rhodopsin Chromophore
Published in Journal of chemical theory and computation (12-03-2013)“…The ASEP/MD (averaged solvent electrostatic potential from molecular dynamics) method was employed in studying the environment effects (solvent and counterion)…”
Get full text
Journal Article -
16
Theoretical Study of the Dual Fluorescence of 4-(N,N-Dimethylamino)benzonitrile in Solution
Published in Journal of chemical theory and computation (10-08-2010)“…We have performed high-level quantum calculations of absorption and emission properties of 4-(N,N-dimethylamino)benzonitrile (DMABN) in gas phase and in polar…”
Get full text
Journal Article -
17
Solvent Effects on the Absorption Spectra of the para-Coumaric Acid Chromophore in Its Different Protonation Forms
Published in Journal of chemical theory and computation (08-10-2013)“…The effects of the solvent and protonation state on the electronic absorption spectrum of the para-coumaric acid (pCA), a model of the photoactive yellow…”
Get full text
Journal Article -
18
Study on the conformational equilibrium of the alanine dipeptide in water solution by using the averaged solvent electrostatic potential from molecular dynamics methodology
Published in The Journal of chemical physics (21-11-2011)“…The ASEP/MD method has been employed for studying the solvent effect on the conformational equilibrium of the alanine dipeptide in water solution. MP2 and…”
Get more information
Journal Article -
19
Solvent Effects on the Radiative and Nonradiative Decay of a Model of the Rhodopsin Chromophore
Published in Journal of chemical theory and computation (13-12-2011)“…The radiative and nonradiative decay of a model with five double bonds of the 11-cis-retinal protonated Schiff base was studied both in vacuum and in methanol…”
Get full text
Journal Article -
20
Apoptosis-related proteins are potential markers of neonatal hypoxic–ischemic encephalopathy (HIE) injury
Published in Neuroscience letters (13-01-2014)“…•TUNEL positive cells are present in damaged areas undetectable by histological exam.•Expression of Smac-DIABLO and cathepsin D (CTSD) shows the same regional…”
Get full text
Journal Article