Search Results - "Martín, M. E."

Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative by Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, J A, Salliot, C, Trudeau, J, Bombardier, C, Carmona, L, van der Heijde, D, Bijlsma, J W J, Boumpas, D T, Canhao, H, Edwards, C J, Hamuryudan, V, Kvien, T K, Leeb, B F, Martín-Mola, E M, Mielants, H, Müller-Ladner, U, Murphy, G, Østergaard, M, Pereira, I A, Ramos-Remus, C, Valentini, G, Zochling, J, Dougados, M

“…To develop evidence-based recommendations for the use of methotrexate in daily clinical practice in rheumatic disorders. 751 rheumatologists from 17 countries…”
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A computer-aided design tool for biomedical OBT sensor tuning in cell-culture assays by Pérez, P., Serrano, J.A., Martín, M.E., Daza, P., Huertas, G., Yúfera, A.

“…•A CAD tool for real-time cell culture monitoring system design is developed•Generates an equivalent electric circuit for the cell-electrode based on area cell…”
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Substituent and Solvent Effects on the UV–vis Absorption Spectrum of the Photoactive Yellow Protein Chromophore by García-Prieto, F. Fernández, Aguilar, M. A, Galván, I. Fdez, Muñoz-Losa, A, Olivares del Valle, F. J, Sánchez, M. L, Martín, M. E

“…Solvent effects on the UV–vis absorption spectra and molecular properties of four models of the photoactive yellow protein (PYP) chromophore have been studied…”
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Utility of the Spanish version of the Everyday Cognition scale in the diagnosis of mild cognitive impairment and mild dementia in an older cohort from the Argentina-ADNI by Russo, María Julieta, Cohen, G., Chrem Mendez, P., Campos, J., Martín, M. E., Clarens, M. F., Tapajoz, F., Harris, P., Sevlever, G., Allegri, R. F.

“…Introduction The performance of activities of daily living in elderly patients with memory disorders is directly related to living independently and to…”
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Picoplankton Carbon Biomass Assessments and Distribution of Prochlorococcus Ecotypes Linked to Loop Current Eddies During Summer in the Southern Gulf of Mexico by Linacre, L., Durazo, R., Camacho‐Ibar, V. F., Selph, K. E., Lara‐Lara, J. R., Mirabal‐Gómez, U., Bazán‐Guzmán, C., Lago‐Lestón, A., Fernández‐Martín, E. M., Sidón‐Ceseña, K.

“…Assessments of picoplankton carbon biomass in the pelagic ecosystem over the deep region of the southern Gulf of Mexico were conducted during three consecutive…”
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Schwannoma of the biliary tract resembling cholangiocarcinoma: A case report and review by Marin Campos, C, Garcia Sanz, I, Muñoz de Nova, J L, Valdés de Anca, A, Martín Pérez, M E

“…Schwannomas are benign tumours derived from Schwann cells and are extremely rare in the biliary tract. We present the case of a 62-year-old patient with a…”
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Micronised bran-enriched fresh egg tagliatelle: Significance of gums addition on pasta technological features by Martín-Esparza, ME, Raga, A, González-Martínez, C, Albors, A

“…The aim of the work was to produce fibre-enriched fresh pasta based on micronised wheat bran and durum wheat semolina with appropriate techno-functional…”
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Update on radioguided surgery: from international consensus on sentinel node in head and neck cancer to the advances on gynaecological tumors and localization of non-palpable lesions by Vidal-Sicart, S, Fuertes Cabero, S, Danús Lainez, M, Valdés Olmos, R, Paredes Barranco, P, Rayo Madrid, J I, Rioja Martín, M E, Díaz Expósito, R, Goñi Gironés, E

“…The aim of this review is to provide an updated perspective on different fields of radioguided surgery. With reference to the sentinel lymph node biopsy in…”
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Prospective randomized 1-year follow-up comparison of bilateral subthalamotomy versus bilateral subthalamic stimulation and the combination of both in Parkinson's disease patients: a pilot study by Merello, M., Tenca, E., Lloret, S. Pérez, Martín, M. E., Bruno, V., Cavanagh, S., Antico, J., Cerquetti, D., Leiguarda, R.

“…It has been suggested that potential risk of hemiballismus after subthalamotomy makes DBS preferable to ablation for IPD treatment; however, cost and the need…”
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Review of the role of the sentinel node biopsy in neoadjuvant chemotherapy in women with breast cancer and negative or positive axillary node at diagnosis by Ruano Pérez, R, Rebollo Aguirre, A C, García-Talavera San Miguel, P, Díaz Expósito, R, Vidal-Sicart, S, Cordero García, J M, Carrera Salazar, D, Rioja Martín, M E

“…The role of the selective sentinel node biopsy (SNB) is increasing in relevance in breast cancer women with indication of neoadjuvant chemotherapy (NAC). The…”
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PAni/SBR composite as anticorrosive coating for carbon steel, part II: electrochemical characterization by De León-Almazán, C. M., Onofre-Bustamante, E., Rivera-Armenta, J. L., Ángeles San Martín, M. E., Chávez-Cinco, M. Y., Gallardo-Rivas, N. V., Páramo-García, U.

“…Conducting polymer composites have gained popularity into the field of organic anticorrosive coatings research due to their low environmental and health…”
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Diagnosis of amyopathic dermatomyositis after two intrauterine fetal deaths by Alonso-Espías, M, Martínez-Sánchez, N, Robles-Marhuenda, A, Martín-Boado, ME, Regojo-Zapata, RM, Bartha, JL

“…Chronic histiocytic intervillositis (CHIV) is an uncommon condition, characterized by an infiltrate of mononuclear cells of maternal origin in the intervillous…”
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Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease by Douangamath, Alice, Fearon, Daren, Gehrtz, Paul, Krojer, Tobias, Lukacik, Petra, Owen, C. David, Resnick, Efrat, Strain-Damerell, Claire, Aimon, Anthony, Ábrányi-Balogh, Péter, Brandão-Neto, José, Carbery, Anna, Davison, Gemma, Dias, Alexandre, Downes, Thomas D., Dunnett, Louise, Fairhead, Michael, Firth, James D., Jones, S. Paul, Keeley, Aaron, Keserü, György M., Klein, Hanna F., Martin, Mathew P., Noble, Martin E. M., O’Brien, Peter, Powell, Ailsa, Reddi, Rambabu N., Skyner, Rachael, Snee, Matthew, Waring, Michael J., Wild, Conor, London, Nir, von Delft, Frank, Walsh, Martin A.

“…COVID-19, caused by SARS-CoV-2, lacks effective therapeutics. Additionally, no antiviral drugs or vaccines were developed against the closely related…”
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FragLitesMinimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation by Wood, Daniel J, Lopez-Fernandez, J. Daniel, Knight, Leanne E, Al-Khawaldeh, Islam, Gai, Conghao, Lin, Shengying, Martin, Mathew P, Miller, Duncan C, Cano, Céline, Endicott, Jane A, Hardcastle, Ian R, Noble, Martin E. M, Waring, Michael J

“…Identifying ligand binding sites on proteins is a critical step in target-based drug discovery. Current approaches to this require resource-intensive screening…”
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CDK1 structures reveal conserved and unique features of the essential cell cycle CDK by Brown, Nicholas R., Korolchuk, Svitlana, Martin, Mathew P., Stanley, Will A., Moukhametzianov, Rouslan, Noble, Martin E. M., Endicott, Jane A.

“…CDK1 is the only essential cell cycle CDK in human cells and is required for successful completion of M-phase. It is the founding member of the CDK family and…”
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Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors by Lochhead, Pamela A., Tucker, Julie A., Tatum, Natalie J., Wang, Jinhua, Oxley, David, Kidger, Andrew M., Johnson, Victoria P., Cassidy, Megan A., Gray, Nathanael S., Noble, Martin E. M., Cook, Simon J.

“…The dual protein kinase-transcription factor, ERK5, is an emerging drug target in cancer and inflammation, and small-molecule ERK5 kinase inhibitors have been…”
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Cryo-EM structure of the CDK2-cyclin A-CDC25A complex by Rowland, Rhianna J., Korolchuk, Svitlana, Salamina, Marco, Tatum, Natalie J., Ault, James R., Hart, Sam, Turkenburg, Johan P., Blaza, James N., Noble, Martin E. M., Endicott, Jane A.

“…The cell division cycle 25 phosphatases CDC25A, B and C regulate cell cycle transitions by dephosphorylating residues in the conserved glycine-rich loop of…”
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Protein Kinase Inhibitors: Insights into Drug Design from Structure by Martin E. M. Noble, Endicott, Jane A., Johnson, Louise N.

“…Protein kinases are targets for treatment of a number of diseases. This review focuses on kinase inhibitors that are in the clinic or in clinical trials and…”
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Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1 by Rowland, Rhianna J., Heath, Richard, Maskell, Daniel, Thompson, Rebecca F., Ranson, Neil A., Blaza, James N., Endicott, Jane A., Noble, Martin E. M., Salamina, Marco

“…p27KIP1 (cyclin-dependent kinase inhibitor 1B, p27) is a member of the CIP/KIP family of CDK (cyclin dependent kinase) regulators that inhibit cell cycle CDKs…”
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The Structural Basis for Control of Eukaryotic Protein Kinases by Endicott, Jane A, Noble, Martin E.M, Johnson, Louise N

“…Eukaryotic protein kinases are key regulators of cell processes. Comparison of the structures of protein kinase domains, both alone and in complexes, allows…”
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