Search Results - "Marston, James P."
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1
Anionic Charge Is Prioritized over Geometry in Aluminum and Magnesium Fluoride Transition State Analogs of Phosphoryl Transfer Enzymes
Published in Journal of the American Chemical Society (26-03-2008)“…Phosphoryl transfer reactions are ubiquitous in biology and metal fluoride complexes have played a central role in structural approaches to understanding how…”
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2
The Denatured State of N-PGK Is Compact and Predominantly Disordered
Published in Journal of molecular biology (09-01-2009)“…The organisation of the structure present in the chemically denatured N-terminal domain of phosphoglycerate kinase (N-PGK) has been determined by paramagnetic…”
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Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis
Published in Journal of the American Chemical Society (12-05-2010)“…Transition state analogue (TSA) complexes formed by phosphoglycerate kinase (PGK) have been used to test the hypothesis that balancing of charge within the…”
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4
Prioritization of Charge over Geometry in Transition State Analogues of a Dual Specificity Protein Kinase
Published in Journal of the American Chemical Society (23-03-2011)“…The direct observation of a transition state analogue (TSA) complex for tyrosine phosphorylation by a signaling kinase has been achieved using 19F NMR analysis…”
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5
Structural Tightening and Interdomain Communication in the Catalytic Cycle of Phosphoglycerate Kinase
Published in Journal of molecular biology (19-02-2010)“…Changes in amide-NH chemical shift and hydrogen exchange rates as phosphoglycerate kinase progresses through its catalytic cycle have been measured to assess…”
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