Search Results - "Marsman, D S"

Nutrition interventions for healthy ageing across the lifespan: a conference report by Kalache, A., de Hoogh, A. I., Howlett, S. E., Kennedy, B., Eggersdorfer, M., Marsman, D. S., Shao, A., Griffiths, J. C.

“…Thanks to advances in modern medicine over the past century, the world’s population has experienced a marked increase in longevity. However, disparities exist…”
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Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Hazard to Humans? by Cattley, Russell C., DeLuca, John, Elcombe, Cliff, Fenner-Crisp, Penelope, Lake, Brian G., Marsman, Daniel S., Pastoor, Timothy A., Popp, James A., Robinson, Denise E., Schwetz, Bernard, Tugwood, Jonathan, Wahli, Walter

“…The purpose of the workshop “Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Hazard to Humans?” was to provide a review of the current state of…”
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Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators Di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats by MARSMAN, D. S, CATTLEY, R. C, CONWAY, J. G, POPP, J. A

“…The mechanism of hepatocarcinogenesis caused by peroxisome proliferators (PP) is poorly understood, making it difficult to predict the carcinogenicity of PP to…”
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Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643 by Marsman, D S, Popp, J A

“…The biological potential of hepatic foci and tumors induced by peroxisome proliferators such as Wy-14,643 has been poorly characterized. In this study, male…”
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Rat 17 beta-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene by Corton, J C, Bocos, C, Moreno, E S, Merritt, A, Marsman, D S, Sausen, P J, Cattley, R C, Gustafsson, J A

“…To better understand the molecular mechanisms of the pleiotropic responses induced by exposure to peroxisome proliferator chemicals (PPCs), we conducted a…”
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Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver by Cattley, R C, Marsman, D S, Popp, J A

“…The carcinogenicity of the peroxisome proliferator WY-14,643 was compared in young (starting age 2 months) and old (starting age 15 months) rats. Old rats had…”
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Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens Wy-14,643 and clofibric acid by Marsman, D S, Goldsworthy, T L, Popp, J A

“…Earlier studies indicated that the hepatocarcinogenic activity of two peroxisome proliferators (PP) Wy-14,643 and di(2-ethylhexyl)phthalate (DEHP) correlated…”
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Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643 by Conway, J G, Tomaszewski, K E, Olson, M J, Cattley, R C, Marsman, D S, Popp, J A

“…Quantitative comparisons of the time course of biochemical and morphological changes induced by peroxisome proliferators resulting in low and high incidences…”
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TGF alpha differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion by Miller, R T, Cattley, R C, Marsman, D S, Lyght, O, Popp, J A

“…Transforming growth factor alpha (TGF alpha) is a mitogenic growth factor for hepatocytes that may play a role in the development of liver cancer in rodents…”
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Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation by Keller, B J, Marsman, D S, Popp, J A, Thurman, R G

“…A number of plasticizers and lipid-lowering drugs induce peroxisomes and cause hepatocellular carcinoma in rodents by mechanisms which remain unknown. In this…”
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Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, Wy-14,643 and clofibric acid by Marsman, D S, Swanson-Pfeiffer, C L, Popp, J A

“…Hepatocyte replication is an early biological response in rodents following administration of peroxisome proliferators (PP); however, the mechanism for this…”
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Retrospective assessment of liver cell proliferation via PCNA: a comparison with tritiated thymidine by Dietrich, D R, Candrian, R, Marsman, D S, Popp, J A, Kaufmann, W K, Swenberg, J A

“…Cell proliferation (S phase response) in archival liver tissues of partially hepatectomized rats was determined via proliferating cell nuclear antigen (PCNA)…”
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Safety evaluation of superabsorbent baby diapers by Kosemund, Kirstin, Schlatter, Harald, Ochsenhirt, Jennifer L., Krause, Edburga L., Marsman, Daniel S., Erasala, Geetha N.

“…Superabsorbent disposable baby diapers are sophisticated, well-engineered products that provide many benefits including convenience, comfort, exceptional…”
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Nutrition interventions for healthy ageing across the lifespan: a conference report by Kalache, A., de Hoogh, A. I., Howlett, S. E., Kennedy, B., Eggersdorfer, M., Marsman, D. S., Shao, A., Griffiths, J. C.

“…Thanks to advances in modern medicine over the past century, the world’s population has experienced a marked increase in longevity. However, disparities exist…”
Get full text

Dose-related effects of the hepatocarcinogen, Wy-14,643, on peroxisomes and cell replication by Wada, N, Marsman, D S, Popp, J A

“…The dose and time dependency of peroxisome proliferation and hepatocyte replication was evaluated in the liver of rats fed the peroxisome proliferator and…”
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The nongenotoxic hepatocarcinogen Wy-14,643 is an uncoupler of oxidative phosphorylation in vivo by Keller, B J, Bradford, B U, Marsman, D S, Cattley, R C, Popp, J A, Bojes, H K, Thurman, R G

“…Wy-14,643 is a potent nongenotoxic hepatic carcinogen and peroxisome proliferator in rodents; however, the mechanism by which it causes tumors remains unknown…”
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Chemically induced cell proliferation in liver carcinogenesis by Popp, J A, Marsman, D S

“…Hepatocyte proliferation has been noted in several stages of the hepatocarcinogenic process. Immediately associated with DNA adducts, hepatocyte proliferation…”
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Failure of the peroxisome proliferator WY-14,643 to initiate growth-selectable foci in rat liver by Cattley, R C, Marsman, D S, Popp, J A

“…The ability of the peroxisome proliferator WY-14,643 to act as an initiator of hepatocarcinogenesis was examined using a modified growth-selection protocol in…”
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Relationship of peroxisome proliferator-induced cellular effects to hepatocarcinogenesis by Popp, J A, Cattley, R C, Miller, R T, Marsman, D S

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Cell proliferation and promotion in the hepatocarcinogenicity of peroxisome proliferating chemicals by Cattley, R C, Marsman, D S, Popp, J A

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