Search Results - "Marsicano, Giovanni"

CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity by Busquets-Garcia, Arnau, Bains, Jaideep, Marsicano, Giovanni

“…Endocannabinoids (eCBs) are amongst the most ubiquitous signaling molecules in the nervous system. Over the past few decades, observations based on a large…”
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Structural basis of astrocytic Ca2+ signals at tripartite synapses by Arizono, Misa, Inavalli, V. V. G. Krishna, Panatier, Aude, Pfeiffer, Thomas, Angibaud, Julie, Levet, Florian, Ter Veer, Mirelle J. T., Stobart, Jillian, Bellocchio, Luigi, Mikoshiba, Katsuhiko, Marsicano, Giovanni, Weber, Bruno, Oliet, Stéphane H. R., Nägerl, U. Valentin

“…Astrocytic Ca 2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis…”
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Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity by Corkrum, Michelle, Covelo, Ana, Lines, Justin, Bellocchio, Luigi, Pisansky, Marc, Loke, Kelvin, Quintana, Ruth, Rothwell, Patrick E., Lujan, Rafael, Marsicano, Giovanni, Martin, Eduardo D., Thomas, Mark J., Kofuji, Paulo, Araque, Alfonso

“…Dopamine is involved in physiological processes like learning and memory, motor control and reward, and pathological conditions such as Parkinson’s disease and…”
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Synapse-specific astrocyte gating of amygdala-related behavior by Martin-Fernandez, Mario, Jamison, Stephanie, Robin, Laurie M, Zhao, Zhe, Martin, Eduardo D, Aguilar, Juan, Benneyworth, Michael A, Marsicano, Giovanni, Araque, Alfonso

“…Astrocytes differentially regulate excitatory and inhibitory synaptic transmission in the CeM, the major output nucleus of the amygdala. Astrocytes thereby…”
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Glucose metabolism links astroglial mitochondria to cannabinoid effects by Jimenez-Blasco, Daniel, Busquets-Garcia, Arnau, Hebert-Chatelain, Etienne, Serrat, Roman, Vicente-Gutierrez, Carlos, Ioannidou, Christina, Gómez-Sotres, Paula, Lopez-Fabuel, Irene, Resch-Beusher, Monica, Resel, Eva, Arnouil, Dorian, Saraswat, Dave, Varilh, Marjorie, Cannich, Astrid, Julio-Kalajzic, Francisca, Bonilla-Del Río, Itziar, Almeida, Angeles, Puente, Nagore, Achicallende, Svein, Lopez-Rodriguez, Maria-Luz, Jollé, Charlotte, Déglon, Nicole, Pellerin, Luc, Josephine, Charlène, Bonvento, Gilles, Panatier, Aude, Lutz, Beat, Piazza, Pier-Vincenzo, Guzmán, Manuel, Bellocchio, Luigi, Bouzier-Sore, Anne-Karine, Grandes, Pedro, Bolaños, Juan P., Marsicano, Giovanni

“…Astrocytes take up glucose from the bloodstream to provide energy to the brain, thereby allowing neuronal activity and behavioural responses 1 – 5 . By…”
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Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling by Ozaita, Andrés, Maldonado, Rafael, Puighermanal, Emma, Marsicano, Giovanni, Busquets-Garcia, Arnau, Lutz, Beat

“…Cannabis can impair memory function. This study shows that, in mice, the active component of cannabis, via CB1 receptors on GABA interneurons and a mechanism…”
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Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum by Puighermanal, Emma, Castell, Laia, Esteve-Codina, Anna, Melser, Su, Kaganovsky, Konstantin, Zussy, Charleine, Boubaker-Vitre, Jihane, Gut, Marta, Rialle, Stephanie, Kellendonk, Christoph, Sanz, Elisenda, Quintana, Albert, Marsicano, Giovanni, Martin, Miquel, Rubinstein, Marcelo, Girault, Jean-Antoine, Ding, Jun B., Valjent, Emmanuel

“…Action control is a key brain function determining the survival of animals in their environment. In mammals, neurons expressing dopamine D2 receptors (D2R) in…”
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Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system? by Fernández-Moncada, Ignacio, Marsicano, Giovanni

“…Astrocytes are key players in brain homeostasis and function. During the last years, several studies have cemented this notion by showing that these cells…”
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Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory by Robin, Laurie M., Oliveira da Cruz, José F., Langlais, Valentin C., Martin-Fernandez, Mario, Metna-Laurent, Mathilde, Busquets-Garcia, Arnau, Bellocchio, Luigi, Soria-Gomez, Edgar, Papouin, Thomas, Varilh, Marjorie, Sherwood, Mark W., Belluomo, Ilaria, Balcells, Georgina, Matias, Isabelle, Bosier, Barbara, Drago, Filippo, Van Eeckhaut, Ann, Smolders, Ilse, Georges, Francois, Araque, Alfonso, Panatier, Aude, Oliet, Stéphane H.R., Marsicano, Giovanni

“…Bidirectional communication between neurons and astrocytes shapes synaptic plasticity and behavior. D-serine is a necessary co-agonist of synaptic…”
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CB1R-dependent regulation of astrocyte physiology and astrocyte-neuron interactions by Covelo, Ana, Eraso-Pichot, Abel, Fernández-Moncada, Ignacio, Serrat, Román, Marsicano, Giovanni

“…The endocannabinoid system (ECS) is involved in a variety of brain functions, mainly through the activation of the type-1 cannabinoid receptors (CB1R). CB1R…”
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Dissecting the cannabinergic control of behavior: The where matters by Busquets‐Garcia, Arnau, Desprez, Tifany, Metna‐Laurent, Mathilde, Bellocchio, Luigi, Marsicano, Giovanni, Soria‐Gomez, Edgar

“…The endocannabinoid system is the target of the main psychoactive component of the plant Cannabis sativa, the Δ⁹‐tetrahydrocannabinol (THC). This system is…”
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Acute Cannabinoids Impair Working Memory through Astroglial CB1 Receptor Modulation of Hippocampal LTD by Han, Jing, Kesner, Philip, Metna-Laurent, Mathilde, Duan, Tingting, Xu, Lin, Georges, Francois, Koehl, Muriel, Abrous, Djoher Nora, Mendizabal-Zubiaga, Juan, Grandes, Pedro, Liu, Qingsong, Bai, Guang, Wang, Wei, Xiong, Lize, Ren, Wei, Marsicano, Giovanni, Zhang, Xia

“…Impairment of working memory is one of the most important deleterious effects of marijuana intoxication in humans, but its underlying mechanisms are presently…”
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Two-Photon Excitation STED Microscopy in Two Colors in Acute Brain Slices by Bethge, Philipp, Chéreau, Ronan, Avignone, Elena, Marsicano, Giovanni, Nägerl, U. Valentin

“…Many cellular structures and organelles are too small to be properly resolved by conventional light microscopy. This is particularly true for dendritic spines…”
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Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages by Ruiz de Azua, Inigo, Mancini, Giacomo, Srivastava, Raj Kamal, Rey, Alejandro Aparisi, Cardinal, Pierre, Tedesco, Laura, Zingaretti, Cristina Maria, Sassmann, Antonia, Quarta, Carmelo, Schwitter, Claudia, Conrad, Andrea, Wettschureck, Nina, Vemuri, V Kiran, Makriyannis, Alexandros, Hartwig, Jens, Mendez-Lago, Maria, Bindila, Laura, Monory, Krisztina, Giordano, Antonio, Cinti, Saverio, Marsicano, Giovanni, Offermanns, Stefan, Nisoli, Enzo, Pagotto, Uberto, Cota, Daniela, Lutz, Beat

“…Dysregulated adipocyte physiology leads to imbalanced energy storage, obesity, and associated diseases, imposing a costly burden on current health care…”
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance by Pagotto, Uberto, Marsicano, Giovanni, Cota, Daniela, Lutz, Beat, Pasquali, Renato

“…During the last few years, the endocannabinoid system has emerged as a highly relevant topic in the scientific community. Many different regulatory actions…”
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Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice by Dubreucq, Sarah, Matias, Isabelle, Cardinal, Pierre, Häring, Martin, Lutz, Beat, Marsicano, Giovanni, Chaouloff, Francis

“…The endocannabinoid system (ECS) tightly controls emotional responses to acute aversive stimuli. Repeated stress alters ECS activity but the role played by the…”
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An enquiry to the role of CB1 receptors in neurodegeneration by Fernández-Moncada, Ignacio, Eraso-Pichot, Abel, Dalla Tor, Tommaso, Fortunato-Marsol, Bérénice, Marsicano, Giovanni

“…Neurodegenerative disorders are debilitating conditions that impair patient quality of life and that represent heavy social-economic burdens to society…”
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Pregnenolone Can Protect the Brain from Cannabis Intoxication by Vallée, Monique, Vitiello, Sergio, Bellocchio, Luigi, Hébert-Chatelain, Etienne, Monlezun, Stéphanie, Martin-Garcia, Elena, Kasanetz, Fernando, Baillie, Gemma L., Panin, Francesca, Cathala, Adeline, Roullot-Lacarrière, Valérie, Fabre, Sandy, Hurst, Dow P., Lynch, Diane L., Shore, Derek M., Deroche-Gamonet, Véronique, Spampanato, Umberto, Revest, Jean-Michel, Maldonado, Rafael, Reggio, Patricia H., Ross, Ruth A., Marsicano, Giovanni, Piazza, Pier Vincenzo

“…Pregnenolone is considered the inactive precursor of all steroid hormones, and its potential functional effects have been largely uninvestigated. The…”
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Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice by Osei-Hyiaman, Douglas, Liu, Jie, Zhou, Liang, Godlewski, Grzegorz, Harvey-White, Judith, Jeong, Won-il, Bátkai, Sándor, Marsicano, Giovanni, Lutz, Beat, Buettner, Christoph, Kunos, George

“…Diet-induced obesity is associated with fatty liver, insulin resistance, leptin resistance, and changes in plasma lipid profile. Endocannabinoids have been…”
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Bimodal control of stimulated food intake by the endocannabinoid system by Puente, Nagore, Cannich, Astrid, Piazza, Pier Vincenzo, Chaouloff, Francis, Grandes, Pedro, Marsicano, Giovanni, Cota, Daniela, Bellocchio, Luigi, Lafenêtre, Pauline

“…Activation of cannabinoid type-1 receptors (CB1) is universally recognized as a powerful endogenous orexigenic signal, but the detailed underlying neuronal…”
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