Search Results - "Marshall, John"
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Why have clinical trials in sepsis failed?
Published in Trends in molecular medicine (01-04-2014)“…Highlights • The biology of sepsis is complex and not specific to infection. • Clinical criteria do not adequately delineate patients who will benefit from…”
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A clinical case definition of post-COVID-19 condition by a Delphi consensus
Published in The Lancet infectious diseases (01-04-2022)“…People with COVID-19 might have sustained postinfection sequelae. Known by a variety of names, including long COVID or long-haul COVID, and listed in the…”
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3
Closure of the meridional overturning circulation through Southern Ocean upwelling
Published in Nature geoscience (01-03-2012)“…The meridional overturning circulation of the ocean plays a central role in climate and climate variability by storing and transporting heat, fresh water and…”
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4
Polycystic Ovary Syndrome
Published in The New England journal of medicine (07-07-2016)“…The polycystic ovary syndrome increases the risk of infertility, endometrial cancer, abnormal glucose metabolism, and dyslipidemia. Strategies such as…”
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5
Integrins as Therapeutic Targets: Successes and Cancers
Published in Cancers (23-08-2017)“…Integrins are transmembrane receptors that are central to the biology of many human pathologies. Classically mediating cell-extracellular matrix and cell-cell…”
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Observations, inferences, and mechanisms of the Atlantic Meridional Overturning Circulation: A review
Published in Reviews of geophysics (1985) (01-03-2016)“…This is a review about the Atlantic Meridional Overturning Circulation (AMOC), its mean structure, temporal variability, controlling mechanisms, and role in…”
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Biomarkers of sepsis: time for a reappraisal
Published in Critical care (London, England) (05-06-2020)“…Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic functions. In a previous review, we identified 3370 references reporting on 178…”
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Clinical implications of the mechanism of epidermal growth factor receptor inhibitors
Published in Cancer (15-09-2006)“…Novel therapeutic agents that target the epidermal growth factor receptor (EGFR) constitute an important addition to the therapeutic armamentarium for the…”
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Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials
Published in PloS one (25-10-2012)“…Mesenchymal stromal cells (MSCs, "adult stem cells") have been widely used experimentally in a variety of clinical contexts. There is interest in using these…”
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10
Environmental and physiological determinants of carbon isotope discrimination in terrestrial plants
Published in The New phytologist (01-12-2013)“…Stable carbon isotope ratios (δ13C) of terrestrial plants are employed across a diverse range of applications in environmental and plant sciences; however, the…”
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11
The role of integrins in TGFβ activation in the tumour stroma
Published in Cell and tissue research (01-09-2016)“…TGFβ1 is the most pleiotropic of all known cytokines and thus, to avoid uncontrolled TGFβ-activated processes, its activity is tightly regulated. Studies in…”
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12
Sepsis definitions: time for change
Published in The Lancet (British edition) (02-03-2013)“…[...]some degree of host response is actually inherent to the infection; indeed, this is an important component of the difference between infection and mere…”
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13
The Relationship between ITCZ Location and Cross-Equatorial Atmospheric Heat Transport: From the Seasonal Cycle to the Last Glacial Maximum
Published in Journal of climate (01-06-2013)“…The authors quantify the relationship between the location of the intertropical convergence zone (ITCZ) and the atmospheric heat transport across the equator…”
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14
Changes in ITCZ location and cross-equatorial heat transport at the Last Glacial Maximum, Heinrich Stadial 1, and the mid-Holocene
Published in Earth and planetary science letters (15-03-2014)“…Tropical paleoclimate records provide important insights into the response of precipitation patterns and the Hadley circulation to past climate changes…”
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15
The Devonian landscape factory; plant-sediment interactions in the Old Red Sandstone of Svalbard and the rise of vegetation as a biogeomorphic agent
Published in Journal of the Geological Society (01-09-2021)“…The Devonian Period was a crucial interval in the evolution of plants. During its 60 myr duration, it witnessed the successive evolution of roots, wood, trees…”
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16
Transforming insect population control with precision guided sterile males with demonstration in flies
Published in Nature communications (08-01-2019)“…The sterile insect technique (SIT) is an environmentally safe and proven technology to suppress wild populations. To further advance its utility, a novel…”
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Should all women with PCOS be treated for insulin resistance?
Published in Fertility and sterility (2012)“…PRO —A large majority of women with PCOS have insulin resistance, compensatory hyperinsulinemia with consequent reproductive and metabolic abnormalities…”
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18
Borehole Equilibration: Testing a New Method to Monitor the Isotopic Composition of Tree Xylem Water in situ
Published in Frontiers in plant science (15-04-2020)“…Forest water use has been difficult to quantify. One promising approach is to measure the isotopic composition of plant water, e.g., the transpired water vapor…”
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Understanding Arctic Ocean Circulation: A Review of Ocean Dynamics in a Changing Climate
Published in Journal of geophysical research. Oceans (01-04-2020)“…The Arctic Ocean is a focal point of climate change, with ocean warming, freshening, sea‐ice decline, and circulation that link to the changing atmospheric and…”
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20
Choosing the Best Blood Pressure Target for Vasopressor Therapy
Published in JAMA : the journal of the American Medical Association (10-03-2020)Get full text
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