Search Results - "Marshall, F H"

Binding kinetics differentiates functional antagonism of orexin‐2 receptor ligands by Mould, R, Brown, J, Marshall, F H, Langmead, C J

“…Orexin receptor antagonism represents a novel approach for the treatment of insomnia that directly targets sleep/wake regulation. Several such compounds have…”
Get full text

CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain by Clayton, N., Marshall, F.H., Bountra, C., O'Shaughnessy, C.T.

“…The cannabinoid agonist, HU210 has been evaluated in vivo in nociceptive and inflammatory pain models in the rat. The ED 50 for the anti-nociceptive…”
Get full text

G82 Changing the ‘no change’ culture: increasing usefulness of the SCBU ward round by Marshall, HF, Ajitsaria, R, Taylor, AM, Strauss, CE, Davey, N

“…AimThis Quality Improvement project aimed to increase the usefulness of ward rounds in a busy Special Care Baby Unit (SCBU; i.e. low dependency neonatal unit)…”
Get full text

Cholecystokinin modulates the release of dopamine from the anterior and posterior nucleus accumbens by two different mechanisms by Marshall, F H, Barnes, S, Hughes, J, Woodruff, G N, Hunter, J C

“…The effects of various cholecystokinin (CCK)-related peptides were investigated on 35 mM K(+)-stimulated endogenous dopamine release from slices of either…”
Get more information

GABA(B) receptors function as heterodimers by Marshall, F H, White, J, Main, M, Green, A, Wise, A

“…Our current understanding is that functional GABA(B) receptors exist as heterodimers of two related seven-transmembrane proteins, GABA(B)-R1 and GABA(B)-R2…”
Get more information

The pharmacology of GR203040, a novel, potent and selective non‐peptide tachykinin NK1 receptor antagonist by Beattie, D.T., Beresford, I.J.M., Connor, H.E., Marshall, F.H., Hawcock, A.B., Hagan, R.M., Bowers, J., Birch, P.J., Ward, P.

“…1 The in vitro and in vivo pharmacology of GR203040 ((2S, 3S)‐2‐methoxy‐5‐tetrazol‐1‐yl‐benzyl‐(2‐phenyl‐piperidin‐3‐yl)‐amine), a novel, highly potent and…”
Get full text

Heterodimerization is required for the formation of a functional GABA(B) receptor by White, J H, Wise, A, Main, M J, Green, A, Fraser, N J, Disney, G H, Barnes, A A, Emson, P, Foord, S M, Marshall, F H

“…GABA (gamma-aminobutyric acid) is the main inhibitory neurotransmitter in the mammalian central nervous system, where it exerts its effects through ionotropic…”
Get full text

Pharmacological profile of GR117289 in vitro: a novel, potent and specific non‐peptide angiotensin AT1 receptor antagonist by Robertson, M.J., Barnes, J.C., Drew, G.M., Clark, K.L., Marshall, F.H., Michel, A., Middlemiss, D., Ross, B.C., Scopes, D., Dowle, M.D.

“…1 This paper describes the effects of GR117289 (1‐[[3‐bromo‐2‐[2‐(1H‐tetrazol‐5‐yl)phenyl]‐5‐benzofuranyl]methyl]‐2‐butyl‐4‐chloro‐1H‐imidazole‐5‐carboxylic…”
Get full text

Protein-Protein Interaction and Not Glycosylation Determines the Binding Selectivity of Heterodimers between the Calcitonin Receptor-like Receptor and the Receptor Activity-modifying Proteins by Hilairet, S, Foord, S M, Marshall, F H, Bouvier, M

“…The receptor activity-modifying proteins (RAMPs) and the calcitonin receptor-like receptor (CRLR) are both required to generate adrenomedullin (AM) and…”
Get full text

Development of Tolerance in Mice to the Sedative Effects of the Neuroactive Steroid Minaxolone Following Chronic Exposure by Marshall, Fiona H, Stratton, Sharon C, Mullings, Joanne, Ford, Elaine, Worton, Stella P, Oakley, Nigel R, Hagan, Russell M

“…Minaxolone is a potent ligand for the neurosteroid binding site of the GABA A receptor. In radioligand binding studies to rat brain membranes, minaxolone…”
Get full text

Nighttime Variation in Volatile Content of Flowers of the Night Blooming PlantGaura drummondii by Shaver, T. N., Lingren, P. D., Marshall, H. F.

“…Nighttime amounts were determined for five volatile chemicals identified in extracts ofGaura drummondii flowers. The major component (2-methylbutanal oxime,…”
Get full text

RAMPs: accessory proteins for seven transmembrane domain receptors by Foord, Steven M, Marshall, Fiona H

Get full text

Advances in the molecular understanding of GABA(B) receptors by Billinton, A, Ige, A O, Bolam, J P, White, J H, Marshall, F H, Emson, P C

“…The molecular nature of the metabotropic GABA(B) receptor was for some time a mystery, however it was recently discovered that two related G-protein-coupled…”
Get full text

Nighttime variation in volatile content of flowers of the night blooming plant Gaura drummondii by Shaver, T.N. (USDA, Areawide Pest Management Research Unit, College Station, TX.), Lingren, P.D, Marshall, H.F

“…Nighttime amounts were determined for five volatile chemicals identified in extracts of Gaura drummondii flowers. The major component (2-methylbutanal oxime,…”
Get full text

Binding of angiotensin antagonists to rat liver and brain membranes measured ex vivo by Marshall, Fiona H., Clark, Samantha A., Michel, Anton D., Barnes, Julie C.

“…1 The effects of the angiotensin antagonists GR117289, losartan and Sar1Ala8‐angiotensin II on the ex vivo binding of [125I]‐Sar1Ile8‐angiotensin II to rat…”
Get full text

A study of haemostasis following tonsillectomy comparing ligatures with diathermy by Watson, M G, Dawes, P J, Samuel, P R, Marshall, H F, Rayappa, C, Hill, J, Meikle, D, Murty, G E, Deans, J A, Telios, G

“…The use of diathermy to achieve haemostasis after tonsillectomy remains controversial. We have reviewed the English language literature, and found no…”
Get more information

Nasal tuberculosis--an increasing problem? by Johnson, I J, Soames, J V, Marshall, H F

“…Nasal tuberculosis represents a rare manifestation of infection by Mycobacterium tuberculosis: a case is presented together with a review of the literature…”
Get more information

Measuring protein quality by Satterlee, L. D., Marshall, H. F., Tennyson, J. M.

“…An alternative to the time‐consuming and expensive PER assay for measuring food protein quality is needed by the food industry. Many biological and…”
Get full text

Calcium sensing properties of the GABA(B) receptor by Wise, A, Green, A, Main, M J, Wilson, R, Fraser, N, Marshall, F H

“…The GABA(B) receptor has been shown to consist of a heterodimer of two related 7-transmembrane receptors GABAB-R1 and GABA(B)-R2. These receptors share close…”
Get full text

Characterization of cholecystokinin octapeptide‐stimulated endogenous dopamine release from rat nucleus accumbens in vitro by Marshall, F.H., Barnes, S., Pinnock, R.D., Hughes, J.

“…1 The effect of cholecystokinin sulphated octapeptide (CCK8S) on endogenous dopamine release was examined in rat striatal and nucleus accumbens slices, by high…”
Get full text