Search Results - "Marshall, Andrew F"
-
1
miR-153 regulates SNAP-25, synaptic transmission, and neuronal development
Published in PloS one (25-02-2013)“…SNAP-25 is a core component of the trimeric SNARE complex mediating vesicle exocytosis during membrane addition for neuronal growth, neuropeptide/growth factor…”
Get full text
Journal Article -
2
Dysregulation of T lymphocyte proliferative responses in autoimmunity
Published in PloS one (29-08-2014)“…T cells are critically dependent on cellular proliferation in order to carry out their effector functions. Autoimmune strains are commonly thought to have…”
Get full text
Journal Article -
3
Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans
Published in Hypertension (Dallas, Tex. 1979) (01-07-2016)“…Emerging evidence supports an important role for T cells in the genesis of hypertension. Because this work has predominantly been performed in experimental…”
Get full text
Journal Article -
4
Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18
Published in Proceedings of the National Academy of Sciences - PNAS (10-05-2016)“…Interleukin (IL)-18 is an important effector of innate and adaptive immunity, but its expression must also be tightly regulated because it can potentiate…”
Get full text
Journal Article -
5
Regulation of Diabetogenic Immunity by IL-15-Activated Regulatory CD8 T Cells in Type 1 Diabetes
Published in The Journal of immunology (1950) (01-07-2019)“…Unchecked collaboration between islet-reactive T and B lymphocytes drives type 1 diabetes (T1D). In the healthy setting, CD8 T regulatory cells (Tregs)…”
Get full text
Journal Article -
6
Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice
Published in Diabetes (New York, N.Y.) (01-11-2018)“…Autoimmune diseases such as type 1 diabetes (T1D) arise from unrestrained activation of effector lymphocytes that destroy target tissues. Many efforts have…”
Get full text
Journal Article -
7
Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance
Published in Scientific reports (11-09-2017)“…Disruption of the non-classical Major Histocompatibility Complex (MHC) Ib molecule Qa-1 impairs CD8 Treg and natural killer (NK) cell function and promotes a…”
Get full text
Journal Article -
8
Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
Published in Diabetes (New York, N.Y.) (01-01-2017)“…Overcoming the immune response to establish durable immune tolerance in type 1 diabetes remains a substantial challenge. The ongoing effector immune response…”
Get full text
Journal Article -
9
-
10
-
11
Regulation of B lymphocyte responses to Toll-like receptor ligand binding during diabetes prevention in non-obese diabetic (NOD) mice
Published in Journal of diabetes (01-01-2016)“…Background Interactions between genetic risk factors and the environment drive type 1 diabetes (T1D). The system of Toll‐like receptors (TLR) detects these…”
Get full text
Journal Article -
12
An immunosufficient murine model for the study of human islets
Published in Xenotransplantation (Københaven) (01-11-2014)“…For the sake of therapy of diabetes, it is critical to understand human beta cell function in detail in health and disease. Current studies of human beta cell…”
Get full text
Journal Article -
13
Regulation of Diabetogenic Immunity by IL15-activated Regulatory CD8 T cells in Type 1 Diabetes
Published in The Journal of immunology (1950) (24-05-2019)“…Unchecked collaboration between islet-reactive T and B lymphocytes drives Type 1 Diabetes (T1D). In the healthy setting, CD8 T Regulatory Cells (CD8 Tregs)…”
Get full text
Journal Article -
14
Regulation of B lymphocyte responses to T oll‐like receptor ligand binding during diabetes prevention in non‐obese diabetic ( NOD ) mice: 在非肥胖糖尿病(NOD)小鼠的糖尿病预防中B淋巴细胞对Toll样受体配体结合反应的调控作用
Published in Journal of diabetes (01-01-2016)“…Abstract Background Interactions between genetic risk factors and the environment drive type 1 diabetes ( T1D ). The system of T oll‐like receptors ( TLR )…”
Get full text
Journal Article -
15
Regulation of B lymphocyte responses to Toll-like receptor ligand binding during diabetes prevention in non-obese diabetic (NOD) mice; è-(NOD)BèzTollä½"ä½"è°ä½oe
Published in Journal of diabetes (01-01-2016)“…Background Interactions between genetic risk factors and the environment drive type 1 diabetes (T1D). The system of Toll-like receptors (TLR) detects these…”
Get full text
Journal Article -
16
The Regulation of B Lymphocyte Responses to TLR Ligation During Diabetes Prevention in NOD Mice
Published in Journal of diabetes (03-03-2015)Get full text
Journal Article -
17
An Immuno-Sufficient Murine Model for the Study of Human Islets
Published in Xenotransplantation (Københaven) (09-07-2014)Get full text
Journal Article