Search Results - "Marsh, Gemma S."

Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine? by Natanek, Samantha A., Gosker, Harry R., Slot, Ilse G.M., Marsh, Gemma S., Hopkinson, Nicholas S., Man, William D.-C., Tal-Singer, Ruth, Moxham, John, Kemp, Paul R., Schols, Annemie M.W.J., Polkey, Michael I.

“…ABSTRACT Introduction Quadriceps muscle dysfunction is common in COPD. Determining, and, if possible, predicting quadriceps phenotype in COPD is important for…”
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Pathways associated with reduced quadriceps oxidative fibres and endurance in COPD by NATANEK, Samantha A, GOSKER, Harry R, SLOT, Ilse G. M, MARSH, Gemma S, HOPKINSON, Nicholas S, MOXHAM, John, KEMP, Paul R, SCHOLS, Annemie M. W. J, POLKEY, Michael I

“…Reduced quadriceps endurance in chronic obstructive pulmonary disease (COPD) is associated with a predominance of type II glycolytic fibres over type I…”
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MuRF-1 and atrogin-1 protein expression and quadriceps fiber size and muscle mass in stable patients with COPD by Natanek, Samantha A, Riddoch-Contreras, Joanna, Marsh, Gemma S, Hopkinson, Nicholas S, Moxham, John, Man, William D-C, Kemp, Paul R, Polkey, Michael I

“…Animal studies demonstrate the importance of the E3 ubiquitin ligases, Muscle RING-Finger Protein 1 (MuRF-1) and atrogin-1, in muscle protein degradation…”
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p38 mitogen-activated protein kinase is not activated in the quadriceps of patients with stable chronic obstructive pulmonary disease by Riddoch-Contreras, Joanna, George, Tomasz, Natanek, Samantha A, Marsh, Gemma S, Hopkinson, Nicholas S, Tal-Singer, Ruth, Kemp, Paul, Polkey, Michael I

“…Quadriceps weakness is associated with a poor prognosis in COPD. Several data suggest that immobility and muscle wasting may be related through up-regulation…”
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