Search Results - "Marsano, René Massimiliano"

Identification of Bari Transposons in 23 Sequenced Drosophila Genomes Reveals Novel Structural Variants, MITEs and Horizontal Transfer by Palazzo, Antonio, Lovero, Domenica, D'Addabbo, Pietro, Caizzi, Ruggiero, Marsano, René Massimiliano

“…Bari elements are members of the Tc1-mariner superfamily of DNA transposons, originally discovered in Drosophila melanogaster, and subsequently identified in…”
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MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion by Marsano, René Massimiliano, Rötig, Agnes, Calvo, Sarah, Fernandez-Vizarra, Erika, Sarzi, Emmanuelle, Donnini, Claudia, Chan, Alicia, Carrara, Franco, Strisciuglio, Pietro, Spinazzola, Antonella, Viscomi, Carlo, D'Adamo, Pio, Parini, Rossella, DiMauro, Salvatore, Mootha, Vamsi K, Ferrero, Iliana, Tiranti, Valeria, Weiher, Hans, Gasparini, Paolo, Zeviani, Massimo

“…The mitochondrial (mt) DNA depletion syndromes (MDDS) are genetic disorders characterized by a severe, tissue-specific decrease of mtDNA copy number, leading…”
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Transcriptionally promiscuous "blurry" promoters in Tc1/ mariner transposons allow transcription in distantly related genomes by Palazzo, Antonio, Lorusso, Patrizio, Miskey, Csaba, Walisko, Oliver, Gerbino, Andrea, Marobbio, Carlo Marya Thomas, Ivics, Zoltán, Marsano, René Massimiliano

“…We have recently described a peculiar feature of the promoters in two -like elements, and . The AT-richness and the presence of weak core-promoter motifs make…”
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Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders by Lovero, Domenica, Giordano, Luca, Marsano, René Massimiliano, Sanchez-Martinez, Alvaro, Boukhatmi, Hadi, Drechsler, Maik, Oliva, Marta, Whitworth, Alexander J, Porcelli, Damiano, Caggese, Corrado

“…Mitochondrial disorders associated with genetic defects of the ATP synthase are among the most deleterious diseases of the neuromuscular system that primarily…”
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Structural and Comparative Analyses of Insects Suggest the Presence of an Ultra-Conserved Regulatory Element of the Genes Encoding Vacuolar-Type ATPase Subunits and Assembly Factors by Lovero, Domenica, Porcelli, Damiano, Giordano, Luca, Lo Giudice, Claudio, Picardi, Ernesto, Pesole, Graziano, Pignataro, Eugenia, Palazzo, Antonio, Marsano, René Massimiliano

“…Gene and genome comparison represent an invaluable tool to identify evolutionarily conserved sequences with possible functional significance. In this work, we…”
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Hypoglycemic Properties of Leccinum scabrum Extracts-An In Vitro Study on α-Glucosidase and α-Amylase Inhibition and Metabolic Profile Determination by Ferraro, Valeria, Spagnoletta, Anna, Rotondo, Natalie Paola, Marsano, René Massimiliano, Miniero, Daniela Valeria, Balenzano, Gaetano, De Palma, Annalisa, Colletti, Alessandro, Gargano, Maria Letizia, Lentini, Giovanni, Cavalluzzi, Maria Maddalena

“…Type-2 diabetes affects an increasing percentage of the world's population and its control through dietary management, involving the consumption of…”
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Mitochondrial glutamate carriers from Drosophila melanogaster: Biochemical, evolutionary and modeling studies by Lunetti, Paola, Cappello, Anna Rita, Marsano, René Massimiliano, Pierri, Ciro Leonardo, Carrisi, Chiara, Martello, Emanuela, Caggese, Corrado, Dolce, Vincenza, Capobianco, Loredana

“…The mitochondrial carriers are members of a family of transport proteins that mediate solute transport across the inner mitochondrial membrane. Two isoforms of…”
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Salting-Out Approach Is Worthy of Comparison with Ultracentrifugation for Extracellular Vesicle Isolation from Tumor and Healthy Models by Serratì, Simona, Palazzo, Antonio, Lapenna, Annamaria, Mateos, Helena, Mallardi, Antonia, Marsano, René Massimiliano, Quarta, Alessandra, Del Rosso, Mario, Azzariti, Amalia

“…The role of extracellular vesicles (EVs) has been completely re-evaluated in the recent decades, and EVs are currently considered to be among the main players…”
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Functional characterization of the Bari1 transposition system by Palazzo, Antonio, Marconi, Simona, Specchia, Valeria, Bozzetti, Maria Pia, Ivics, Zoltán, Caizzi, Ruggiero, Marsano, René Massimiliano

“…The transposons of the Bari family are mobile genetic elements widespread in the Drosophila genus. However, despite a broad diffusion, virtually no information…”
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"What You Need, Baby, I Got It": Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila by Moschetti, Roberta, Palazzo, Antonio, Lorusso, Patrizio, Viggiano, Luigi, Marsano, René Massimiliano

“…Transposable elements (TEs) are constitutive components of both eukaryotic and prokaryotic genomes. The role of TEs in the evolution of genes and genomes has…”
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Constitutive Heterochromatin in Eukaryotic Genomes: A Mine of Transposable Elements by Marsano, René Massimiliano, Dimitri, Patrizio

“…Transposable elements (TEs) are abundant components of constitutive heterochromatin of the most diverse evolutionarily distant organisms. TEs enrichment in…”
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circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype‐definition in small cell lung cancer by Tolomeo, Doron, Traversa, Debora, Venuto, Santina, Ebbesen, Karoline K., García Rodríguez, Juan L., Tamma, Grazia, Ranieri, Marianna, Simonetti, Giorgia, Ghetti, Martina, Paganelli, Matteo, Visci, Grazia, Liso, Arcangelo, Kok, Klaas, Muscarella, Lucia Anna, Fabrizio, Federico Pio, Frassanito, Maria Antonia, Lamanuzzi, Aurelia, Saltarella, Ilaria, Solimando, Antonio Giovanni, Fatica, Alessandro, Ianniello, Zaira, Marsano, René Massimiliano, Palazzo, Antonio, Azzariti, Amalia, Longo, Vito, Tommasi, Stefania, Galetta, Domenico, Catino, Annamaria, Zito, Alfredo, Mazza, Tommaso, Napoli, Alessandro, Martinelli, Giovanni, Kjems, Jørgen, Kristensen, Lasse Sommer, Vacca, Angelo, Storlazzi, Clelia Tiziana

“…Small cell lung cancer (SCLC) is treated as a homogeneous disease, although the expression of NEUROD1, ASCL1, POU2F3, and YAP1 identifies distinct molecular…”
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Sym1, the yeast ortholog of the MPV17 human disease protein, is a stress-induced bioenergetic and morphogenetic mitochondrial modulator by Dallabona, Cristina, Marsano, René Massimiliano, Arzuffi, Paola, Ghezzi, Daniele, Mancini, Patrizia, Zeviani, Massimo, Ferrero, Iliana, Donnini, Claudia

“…A peculiar form of hepatocerebral mtDNA depletion syndrome is caused by mutations in the MPV17 gene, which encodes a small hydrophobic protein of unknown…”
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Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila by Caizzi, Ruggiero, Moschetti, Roberta, Piacentini, Lucia, Fanti, Laura, Marsano, Renè Massimiliano, Dimitri, Patrizio

“…The term heterochromatin has been long considered synonymous with gene silencing, but it is now clear that the presence of transcribed genes embedded in…”
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Infantile Encephalopathy and Defective Mitochondrial DNA Translation in Patients with Mutations of Mitochondrial Elongation Factors EFG1 and EFTu by Valente, Lucia, Tiranti, Valeria, Marsano, René Massimiliano, Malfatti, Edoardo, Fernandez-Vizarra, Erika, Donnini, Claudia, Mereghetti, Paolo, De Gioia, Luca, Burlina, Alberto, Castellan, Claudio, Comi, Giacomo P., Savasta, Salvatore, Ferrero, Iliana, Zeviani, Massimo

“…Mitochondrial protein translation is a complex process performed within mitochondria by an apparatus composed of mitochondrial DNA (mtDNA)–encoded RNAs and…”
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Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies by Imbrici, Paola, Altamura, Concetta, Camerino, Giulia Maria, Mangiatordi, Giuseppe Felice, Conte, Elena, Maggi, Lorenzo, Brugnoni, Raffaella, Musaraj, Kejla, Caloiero, Roberta, Alberga, Domenico, Marsano, Renè Massimiliano, Ricci, Giulia, Siciliano, Gabriele, Nicolotti, Orazio, Mora, Marina, Bernasconi, Pia, Desaphy, Jean-Francois, Mantegazza, Renato, Camerino, Diana Conte

“…Myotonia congenita is an inherited disease that is characterized by impaired muscle relaxation after contraction caused by loss-of-function mutations in the…”
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Development of anti-somatostatin receptors CAR T cells for treatment of neuroendocrine tumors by Mandriani, Barbara, Pellè, Eleonora, Mannavola, Francesco, Palazzo, Antonio, Marsano, Renè Massimiliano, Ingravallo, Giuseppe, Cazzato, Gerardo, Ramello, Maria Cecilia, Porta, Camillo, Strosberg, Jonathan, Abate-Daga, Daniel, Cives, Mauro

“…BackgroundNeuroendocrine tumors (NETs) overexpress somatostatin receptors (SSTRs).MethodsWe developed a second-generation, ligand-based, anti-SSTR chimeric…”
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The Green Valley of Drosophila melanogaster Constitutive Heterochromatin: Protein-Coding Genes Involved in Cell Division Control by Messina, Giovanni, Prozzillo, Yuri, Bizzochi, Greta, Marsano, Renè Massimiliano, Dimitri, Patrizio

“…Constitutive heterochromatin represents a significant fraction of eukaryotic genomes (10% in Arabidopsis, 20% in humans, 30% in D. melanogaster, and up to 85%…”
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Functional Characterization of Two Novel Mutations in SCN5A Associated with Brugada Syndrome Identified in Italian Patients by Balla, Cristina, Conte, Elena, Selvatici, Rita, Marsano, Renè Massimiliano, Gerbino, Andrea, Farnè, Marianna, Blunck, Rikard, Vitali, Francesco, Armaroli, Annarita, Brieda, Alessandro, Liantonio, Antonella, De Luca, Annamaria, Ferlini, Alessandra, Rapezzi, Claudio, Bertini, Matteo, Gualandi, Francesca, Imbrici, Paola

“…Background. Brugada syndrome (BrS) is an autosomal dominantly inherited cardiac disease characterized by “coved type” ST-segment elevation in the right…”
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What Have We Learned in 30 Years of Investigations on Bari Transposons? by Palazzo, Antonio, Caizzi, Ruggiero, Moschetti, Roberta, Marsano, René Massimiliano

“…Transposable elements (TEs) have been historically depicted as detrimental genetic entities that selfishly aim at perpetuating themselves, invading genomes,…”
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