Search Results - "Marroquin Belaunzaran, Osiris"

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis by Payeli, Sravan K., Kollnberger, Simon, Marroquin Belaunzaran, Osiris, Thiel, Markus, McHugh, Kirsty, Giles, Joanna, Shaw, Jacqueline, Kleber, Sascha, Ridley, Anna, Wong-Baeza, Isabel, Keidel, Sarah, Kuroki, Kimiko, Maenaka, Katsumi, Wadle, Andreas, Renner, Christoph, Bowness, Paul

“…Objective Spondylarthritides (SpA), including ankylosing spondylitis (AS), are common inflammatory rheumatic diseases that are strongly associated with…”
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HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats by Marroquin Belaunzaran, Osiris, Kleber, Sascha, Schauer, Stefan, Hausmann, Martin, Nicholls, Flora, Van den Broek, Maries, Payeli, Sravan, Ciurea, Adrian, Milling, Simon, Stenner, Frank, Shaw, Jackie, Kollnberger, Simon, Bowness, Paul, Petrausch, Ulf, Renner, Christoph

“…HLA-B27 is a common genetic risk factor for the development of Spondyloarthritides (SpA). HLA-B27 can misfold to form cell-surface heavy chain homodimers…”
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Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool by Marroquin Belaunzaran, Osiris, Cordero, Maria Isabel, Setola, Veronica, Bianchi, Siro, Galli, Carmela, Bouche, Nicolas, Mlynarik, Vladimir, Gruetter, Rolf, Sandi, Carmen, Bensadoun, Jean-Charles, Molinari, Maurizio, Aebischer, Patrick

“…Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional…”
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Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells by Schuberth, Petra C, Hagedorn, Christian, Jensen, Shawn M, Gulati, Pratiksha, van den Broek, Maries, Mischo, Axel, Soltermann, Alex, Jüngel, Astrid, Marroquin Belaunzaran, Osiris, Stahel, Rolf, Renner, Christoph, Petrausch, Ulf

“…Malignant pleural mesothelioma (MPM) is an incurable malignant disease, which results from chronic exposition to asbestos in at least 70% of the cases…”
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IOS-1002, a Stabilized HLA-B57 Open Format, Exerts Potent Anti-Tumor Activity by Rafiei, Anahita, Gualandi, Marco, Yang, Chia-Lung, Woods, Richard, Kumar, Anil, Brunner, Kathrin, Sigrist, John, Ebersbach, Hilmar, Coats, Steve, Renner, Christoph, Marroquin Belaunzaran, Osiris

“…HLA-B27 and HLA-B57 are associated with autoimmunity and long-term viral control and protection against HIV and HCV infection; however, their role in cancer…”
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865 iosH2 exerts potent anti-tumor activity by blocking LILRB1/2 and KIR3DL1 receptor signaling by Belaunzaran, Osiris Marroquin, Rafiei, Anahita, Kumar, Anil, Gualandi, Marco, Westphal, Magdalena, Vogt, Lorenz, Smith, Sean, Curran, Michael, Renner, Christoph

“…BackgroundTo develop novel anti-cancer therapeutics we have used a reverse rational approach and searched for human HLA class I molecules known to induce…”
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Pre-clinical testing of malignant fibroblast activation protein-specific re-directed T cells for treatment of pleural mesothelioma by Schuberth, Petra C, Hagedorn, Christian, Jensen, Shawn M, Gulati, Pratiksha, Belaunzaran, Osiris Marroquin, Soltermann, Alex, Jüngel, Astrid, Renner, Christoph, Petrausch, Ulf

“…IntroductionMalignant pleural mesothelioma (MPM) is an incurable malignant disease that results mostly from chronic exposition to asbestos. Fibroblast…”
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Blocking LILRB and KIR receptors by B57 open conformers induces potent antitumor activity and acts synergistically with checkpoint blockade inhibition by Renner, Christoph, Curran, Michael A., Kolibaba, Julia, Liu, Yang, Petrausch, Ulf, Zippelius, Alfred, Stenner, Frank, Rafiei, Anahita, Marroquin Belaunzaran, Osiris

“…Abstract only e14137 Background: HLA open conformers (OC) are defined as HLA class I molecules lacking beta-2-microglobulin (β2m) and peptide. OC can be…”
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216 Anti-tumor activity of iosH2 by blocking LILRB2 receptor signalling by Osiris Marroquin Belaunzaran, Rafiei, Anahita, Kumar, Anil, Kolibaba, Julia, Vogt, Lorenz, Smith, Sean, Renner, Christoph

“…BackgroundThe human leukocyte immunoglobulin-like receptor family B (LILR B) acts as check point blockade of the innate immune system by inhibiting leukocyte…”
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Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply by McHugh, Kirsty, Rysnik, Oliwia, Kollnberger, Simon, Shaw, Jacqueline, Utriainen, Lotta, Al-Mossawi, Mohammad Hussein, Payeli, Sravan, Belaunzaran, Osiris Marroquin, Milling, Simon, Renner, Christoph, Bowness, Paul

“…Cellular expression of non-classical forms of human leukocyte antigen (HLA)-B27 (NC-B27) may be involved in spondyloarthritis (SpA) pathogenesis. We used a…”
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HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats: e0130811 by Belaunzaran, Osiris Marroquin, Kleber, Sascha, Schauer, Stefan, Hausmann, Martin, Nicholls, Flora, Broek, Maries Vanden, Payeli, Sravan, Ciurea, Adrian, Milling, Simon, Stenner, Frank

“…Objectives HLA-B27 is a common genetic risk factor for the development of Spondyloarthritides (SpA). HLA-B27 can misfold to form cell-surface heavy chain…”
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