Search Results - "Marrogi, A"
-
1
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis : A cancer-prone chronic inflammatory disease
Published in Cancer research (Chicago, Ill.) (01-07-2000)“…Ulcerative colitis (UC) is a chronic inflammatory disease that produces reactive oxygen and nitrogen species and increases the risk of colorectal cancer (CRC)…”
Get full text
Journal Article -
2
Treatment of mesothelioma with gene-modified PA1STK cells and ganciclovir: a phase I study
Published in Cancer gene therapy (01-12-2011)“…Mesothelioma is an incurable cancer of the pleura with a life expectancy of less than 1 year. On the basis of in vivo efficacy seen with the herpes simplex…”
Get full text
Journal Article -
3
Study of tumor infiltrating lymphocytes and transforming growth factor‐β as prognostic factors in breast carcinoma
Published in International journal of cancer (21-10-1997)“…Cytokines and growth factors are powerful modulators of the immune response. Their aberrant expression either by the tumor cells or by the tumor infiltrating…”
Get full text
Journal Article -
4
Immune system in suicide-gene therapy
Published in The Lancet (British edition) (04-01-1997)Get more information
Journal Article -
5
Oxidative Stress and p53 Mutations in the Carcinogenesis of Iron Overload-Associated Hepatocellular Carcinoma
Published in JNCI : Journal of the National Cancer Institute (07-11-2001)“…To eliminate any false-positive results, confirmatory standard automated sequencing was performedon each mutation. Del [H11505] deletion; Ins [H11505]…”
Get full text
Journal Article -
6
In vivo analysis of the 'bystander effect': a cytokine cascade
Published in Experimental hematology (01-06-1996)“…The "bystander effect" refers to the death of unmodified tumor cells when in contact with ganciclovir (GCV)-exposed, herpes simplex virus-thymidine kinase…”
Get more information
Journal Article -
7
In situ use of suicide genes for cancer therapy
Published in Seminars in oncology (01-02-1996)“…Gene therapy has now become a standard experimental approach for treating cancers that have failed conventional therapies. As the understanding of the…”
Get more information
Journal Article -
8
Tumor-host interaction : Analysis of cytokines, growth factors, and tumor-infiltrating lymphocytes in ovarian carcinomas
Published in Human pathology (01-03-1997)“…The host-tumor interaction may play an important role in determining tumor progress. Recent studies have shown that this interaction can be influenced by the…”
Get full text
Journal Article -
9
Nitric Oxide Synthase, Cyclooxygenase 2, and Vascular Endothelial Growth Factor in the Angiogenesis of Non-Small Cell Lung Carcinoma
Published in Clinical cancer research (01-12-2000)“…We have investigated the hypothesis that nitric oxide synthase (NOS2), cyclooxygenase-2 (COX2), and vascular endothelial growth factor (VEGF) protein levels…”
Get full text
Journal Article -
10
Increased p53 Mutation Load in Nontumorous Human Liver of Wilson Disease and Hemochromatosis: Oxyradical Overload Diseases
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2000)“…Hemochromatosis and Wilson disease (WD), characterized by the excess hepatic deposition of iron and copper, respectively, produce oxidative stress and increase…”
Get full text
Journal Article -
11
Enhancement of tumor killing using a combination of tumor immunization and HSV-tk suicide gene therapy
Published in International journal of cancer (29-01-1999)“…Tumor cells genetically modified with the herpes simplex virus thymidine kinase (HSV-tk) gene in combination with ganciclovir (GCV) demonstrate a "bystander…”
Get full text
Journal Article -
12
The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells
Published in Cancer letters (08-06-1995)“…We have previously demonstrated that genetically modified syngeneic murine tumor cells (KBALB) expressing the herpes simplex virus thymidine kinase gene…”
Get full text
Journal Article -
13
p53 tumor suppressor gene mutations in transformed cutaneous T-cell lymphoma: A study of 12 cases
Published in Journal of cutaneous pathology (01-09-1999)“…The transformation of cutaneous T‐cell lymphoma (t‐CTCL) is an uncommon phenomenon that is associated with histopathologic changes and follows an aggressive…”
Get full text
Journal Article -
14
Interaction of the Hepatitis B Virus X Protein with the Crm1-dependent Nuclear Export Pathway
Published in The Journal of biological chemistry (22-06-2001)“…The leucine-rich nuclear export signal (NES) is used to shuttle large cellular proteins from the nucleus to the cytoplasm. The nuclear export receptor Crm1 is…”
Get full text
Journal Article -
15
Immunohistochemical detection of Bcl-2 in AIDS-associated and classical Kaposi's sarcoma
Published in The American journal of pathology (01-04-1996)Get full text
Journal Article -
16
Paradoxical Effects of Platelet-Derived Growth Factor-A Overexpression in Malignant Mesothelioma . Antiproliferative Effects In Vitro and Tumorigenic Stimulation In Vivo
Published in American journal of respiratory cell and molecular biology (01-06-2001)“…Malignant mesothelioma is associated with asbestos exposure and remains resistant to all therapeutic intervention. Previous studies have suggested an enhancing…”
Get full text
Journal Article -
17
Pilomatrical neoplasms in children and young adults
Published in The American journal of dermatopathology (01-04-1992)“…Pilomatrixoma, a neoplasm of hair germ matrix origin, is one of the most common cutaneous appendage tumors in patients 20 years of age or younger. Our review…”
Get more information
Journal Article -
18
The treatment of malignant mesothelioma with a gene modified cancer cell line: a phase I study
Published in Human gene therapy (20-11-1998)“…Malignant mesothelioma is a tumor of the pleura for which there is no satisfactory treatment. It is almost universally fatal, regardless of the stage of the…”
Get more information
Journal Article -
19
Expression of costimulatory molecules: B7 and ICAM up-regulation after treatment with a suicide gene
Published in Cancer gene therapy (01-11-1996)“…The herpes simplex virus thymidine kinase gene (HSV-TK) in combination with ganciclovir (GCV), is currently being used in gene therapy-based clinical trials…”
Get more information
Journal Article -
20
The biology of cancer gene therapy
Published in Laboratory investigation (01-02-1995)Get more information
Journal Article