Search Results - "Marra, Amanda N"
-
1
Antennas of organ morphogenesis: the roles of cilia in vertebrate kidney development
Published in Genesis (New York, N.Y. : 2000) (01-09-2016)“…Cilia arose early during eukaryotic evolution, and their structural components are highly conserved from the simplest protists to complex metazoan species. In…”
Get full text
Journal Article -
2
Pathways Regulating Establishment and Maintenance of Cardiac Chamber Identity in Zebrafish
Published in Journal of cardiovascular development and disease (29-01-2021)“…The vertebrate heart is comprised of two types of chambers-ventricles and atria-that have unique morphological and physiological properties. Effective cardiac…”
Get full text
Journal Article -
3
Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development
Published in Developmental biology (15-03-2016)“…Kidney development requires the differentiation and organization of discrete nephron epithelial lineages, yet the genetic and molecular pathways involved in…”
Get full text
Journal Article -
4
Prostaglandin signaling regulates renal multiciliated cell specification and maturation
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2019)“…Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC dysfunction is associated with human…”
Get full text
Journal Article -
5
The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish
Published in Developmental biology (01-01-2017)“…The simplified and genetically conserved zebrafish pronephros is an excellent model to examine the cryptic processes of cell fate decisions during the…”
Get full text
Journal Article -
6
Homeogene emx1 is required for nephron distal segment development in zebrafish
Published in Scientific reports (21-12-2018)“…Vertebrate kidneys contain nephron functional units where specialized epithelial cell types are organized into segments with discrete physiological roles. Many…”
Get full text
Journal Article -
7
The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development
Published in Developmental biology (01-08-2017)“…The zebrafish kidney is conserved with other vertebrates, making it an excellent genetic model to study renal development. The kidney collects metabolic waste…”
Get full text
Journal Article -
8
Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development
Published in Scientific reports (23-04-2019)“…The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in zebrafish are composed of segment…”
Get full text
Journal Article -
9
Visualizing Multiciliated Cells in the Zebrafish Through a Combined Protocol of Whole Mount Fluorescent In Situ Hybridization and Immunofluorescence
Published in Journal of visualized experiments (18-11-2017)“…In recent years, the zebrafish embryo has emerged as a popular model to study developmental biology due to traits such as ex utero embryo development and…”
Get full text
Journal Article -
10
Flat mount preparation for observation and analysis of zebrafish embryo specimens stained by whole mount in situ hybridization
Published in Journal of visualized experiments (17-07-2014)“…The zebrafish embryo is now commonly used for basic and biomedical research to investigate the genetic control of developmental processes and to model…”
Get full text
Journal Article -
11
Visualizing gene expression during zebrafish pronephros development and regeneration
Published in Methods in Kidney Cell Biology Part B (2019)“…The vertebrate kidney is comprised of functional units known as nephrons. Defects in nephron development or activity are a common feature of kidney disease…”
Get full text
Book Chapter Journal Article -
12
-
13
Genetic Mechanisms of Multiciliated Cell Development During Renal Ontogeny
Published 01-01-2019“…For many years, cilia have been appreciated for their role in signal transduction, serving as antennas for mechanosensory cascades and highways of protein…”
Get full text
Dissertation -
14
Genetic Mechanisms of Multiciliated Cell Development during Renal Ontogeny
Published 01-01-2019“…For many years, cilia have been appreciated for their role in signal transduction, serving as antennas for mechanosensory cascades and highways of protein…”
Get full text
Dissertation -
15
Flat Mount Preparation for Observation and Analysis of Zebrafish Embryo Specimens Stained by Whole Mount In situ Hybridization
Published in Journal of visualized experiments (17-07-2014)Get full text
Journal Article