Search Results - "Marquis, Miriam"
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High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia
Published in Blood cancer journal (New York) (19-07-2018)“…In acute myeloid leukemia (AML), risk stratification based on cytogenetics and mutation profiling is essential but remains insufficient to select the optimal…”
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2
The non-classical MAP kinase ERK3 controls T cell activation
Published in PloS one (27-01-2014)“…The classical mitogen-activated protein kinases (MAPKs) ERK1 and ERK2 are activated upon stimulation of cells with a broad range of extracellular signals…”
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3
IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade
Published in Journal of leukocyte biology (01-09-2007)“…IL21 is a Type I cytokine, which uses the common γ chain (γc) in its receptor. As members of the γc cytokine/cytokine receptors family play crucial role in the…”
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4
Selective Expression of Human Immunodeficiency Virus Nef in Specific Immune Cell Populations of Transgenic Mice Is Associated with Distinct AIDS-Like Phenotypes
Published in Journal of Virology (01-10-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
CD8⁺ T Cells but Not Polymorphonuclear Leukocytes Are Required To Limit Chronic Oral Carriage of Candida albicans in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1
Published in Infection and Immunity (01-04-2006)“…Candida albicans causes oropharyngeal candidiasis (OPC) but rarely disseminates to deep organs in human immunodeficiency virus (HIV) infection. Here, we used a…”
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High Expression of SPAG1 Is Associated with a Worse Clinical Outcome in Intermediate Risk Acute Myeloid Leukemia That Can be Partially Overcome By Hematopoietic Stem Cell Transplantation
Published in Blood (29-11-2018)“…Introduction: Acute myeloid leukemia (AML) is a heterogeneous disease with variable responses to therapy and clinical outcomes. Cytogenetics and molecular…”
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7
A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission
Published in Blood (13-11-2019)“…Background: Core-binding factor acute myeloid leukemias (CBF-AML) are characterized by inv(16)/t(16;16)(p13.1;q22) or t(8;21)(q22;q22.1) and encompass a…”
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8
Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin
Published in Leukemia (01-06-2018)“…Acute promyelocytic leukemia (APL) is a medical emergency because of associated lethal early bleeding, a condition preventable by prompt diagnosis and…”
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9
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats
Published in International journal of toxicology (01-01-2023)“…Vaccines containing mRNA with the capacity to self-amplify represent an alternative to the mRNA vaccines that came to prominence during the COVID-19 pandemic…”
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10
Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting
Published in Applied health economics and health policy (01-12-2019)“…Background Current strategies for risk stratification of patients with acute myeloid leukemia assign approximately 40% of patients to the intermediate-risk…”
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11
Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias
Published in Blood (08-12-2017)“…Background: Acute promyelocytic leukemia (APL), characterized by the t(15;17) translocation, represents a favorable-risk subgroup of AML patients when treated…”
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12
HMGA2 Gene Expression Profile Improves Risk Stratification in Acute Myeloid Leukemia
Published in Blood (08-12-2017)“…Introduction: In adult acute myeloid leukemia (AML), clinical outcome is mainly predicted by age, cytogenetics and specific gene mutations (Papaemmanuil et al…”
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13
The atypical MAPK ERK3 controls positive selection of thymocytes
Published in Immunology (01-05-2015)“…Summary Extracellular signal‐regulated kinase 3 (ERK3 )is an atypical member of the mitogen‐activated protein kinase (MAPK) family. We have previously shown…”
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14
The atypical MAPK ERK 3 controls positive selection of thymocytes
Published in Immunology (01-05-2015)“…Summary Extracellular signal‐regulated kinase 3 ( ERK 3 )is an atypical member of the mitogen‐activated protein kinase ( MAPK ) family. We have previously…”
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15
Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease
Published in Blood (02-12-2016)“…Background:Acute promyelocytic leukemia (APL) is a favorable-risk subgroup of AML characterized by the t(15;17) translocation. The leading cause of early death…”
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16
The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival
Published in Molecular and cellular biology (01-09-2014)“…Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-activated protein kinase (MAPK) family whose function is largely unknown…”
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17
Overexpression of IL-21 promotes massive CD8⁺ memory T cell accumulation
Published in European journal of immunology (01-11-2007)“…The ability of IL-21 to promote in vitro T cell survival led us to investigate its biological activity in vivo. We report that overexpression of IL-21 in…”
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18
Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model
Published in Journal of antimicrobial chemotherapy (01-12-2012)“…To evaluate the relative propensities of oritavancin and vancomycin to induce Clostridium difficile infection (CDI) in hamster and in vitro human gut models…”
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Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia
Published in Blood cancer journal (New York) (28-02-2019)“…Since the publication of the original article the authors noticed the the affiliation details for Paresh Vyas are incorrect. The correct affiliation details…”
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20
Altered CD4+ T Cell Phenotype and Function Determine the Susceptibility to Mucosal Candidiasis in Transgenic Mice Expressing HIV-1
Published in The Journal of immunology (1950) (01-07-2006)“…The impairments of protective mucosal immunity which cause susceptibility to oropharyngeal candidiasis (OPC) in HIV infection remain undefined. This study used…”
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