Search Results - "Marquardt, Laura"

Engineering peripheral nerve repair by Marquardt, Laura M, Sakiyama-Elbert, Shelly E

“…Graphical abstract…”
Get full text

Design of Injectable Materials to Improve Stem Cell Transplantation by Marquardt, Laura M., Heilshorn, Sarah C.

“…Stem cell-based therapies are steadily gaining traction for regenerative medicine approaches to treating disease and injury throughout the body. While a…”
Get full text

The diverse roles of hydrogel mechanics in injectable stem cell transplantation by Foster, Abbygail A, Marquardt, Laura M, Heilshorn, Sarah C

“…•Stem cell transplantation by local injection has seen limited clinical success.•Different transplantation stages present different mechanical…”
Get full text

GDNF preconditioning can overcome Schwann cell phenotypic memory by Marquardt, Laura M., Sakiyama-Elbert, Shelly E.

“…While it is known that Schwann cells (SCs) provide cues to enhance regeneration following peripheral nerve injury, the effect of SC phenotypic memory (muscle…”
Get full text

Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy by Marquardt, Laura M, Doulames, Vanessa M, Wang, Alice T, Dubbin, Karen, Suhar, Riley A, Kratochvil, Michael J, Medress, Zachary A, Plant, Giles W, Heilshorn, Sarah C

“…Transplantation of patient-derived Schwann cells is a promising regenerative medicine therapy for spinal cord injuries; however, therapeutic efficacy is…”
Get full text

Effects of borate-based bioactive glass on neuron viability and neurite extension by Marquardt, Laura M., Day, Delbert, Sakiyama-Elbert, Shelly E., Harkins, Amy B.

“…Bioactive glasses have recently been shown to promote regeneration of soft tissues by positively influencing tissue remodeling during wound healing. We were…”
Get full text

Finely Tuned Temporal and Spatial Delivery of GDNF Promotes Enhanced Nerve Regeneration in a Long Nerve Defect Model by Marquardt, Laura M, Ee, Xueping, Iyer, Nisha, Hunter, Daniel, Mackinnon, Susan E, Wood, Matthew D, Sakiyama-Elbert, Shelly E

“…The use of growth factors, such as glial cell line-derived neurotrophic factor (GDNF), for the treatment of peripheral nerve injury has been useful in…”
Get more information

A novel protein‐engineered hepatocyte growth factor analog released via a shear‐thinning injectable hydrogel enhances post‐infarction ventricular function by Steele, Amanda N., Cai, Lei, Truong, Vi N., Edwards, Bryan B., Goldstone, Andrew B., Eskandari, Anahita, Mitchell, Aaron C., Marquardt, Laura M., Foster, Abbygail A., Cochran, Jennifer R., Heilshorn, Sarah C., Woo, Y. Joseph

“…ABSTRACT In the last decade, numerous growth factors and biomaterials have been explored for the treatment of myocardial infarction (MI). While pre‐clinical…”
Get full text

Glial cell line-derived neurotrophic factor promotes increased phenotypic marker expression in femoral sensory and motor-derived Schwann cell cultures by Jesuraj, Nithya J., Marquardt, Laura M., Kwasa, Jasmine A., Sakiyama-Elbert, Shelly E.

“…Schwann cells (SCs) secrete growth factors and extracellular matrix molecules that promote neuronal survival and help guide axons during regeneration…”
Get full text

Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits by Suhar, Riley A, Marquardt, Laura M, Song, Shang, Buabbas, Hana, Doulames, Vanessa M, Johansson, Patrik K, Klett, Katarina C, Dewi, Ruby E, Enejder, Annika M. K, Plant, Giles W, George, Paul M, Heilshorn, Sarah C

“…Synthetic nerve guidance conduits (NGCs) offer an alternative to harvested nerve grafts for treating peripheral nerve injury (PNI). NGCs have been made from…”
Get full text

Group A Streptococcus strains causing meningitis without distinct invasive phenotype by Marquardt, Laura, Andreoni, Federica, Boumasmoud, Mathilde, Schweizer, Tiziano A., Heuberger, Dorothea M., Parietti, Elena, Hertegonne, Sanne, Epprecht, Jana, Mattle, Dario, Raez, Anna K., Marques‐Maggio, Ewerton, Schuepbach, Reto A., Hasse, Barbara, Mairpady‐Shambat, Srikanth, Brugger, Silvio D., Zinkernagel, Annelies S.

“…Group A streptococcal (GAS; aka Streptococcus pyogenes) meningitis is a fulminant disease associated with high morbidity and mortality. To elucidate the…”
Get full text

Viral transduction of primary Schwann cells using a Cre-lox system to regulate GDNF expression by Wu-Fienberg, Yuewei, Moore, Amy M., Marquardt, Laura M., Newton, Piyaraj, Johnson, Philip J., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E., Wood, Matthew D.

“…ABSTRACT Glial cell‐line‐derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to enhance motor nerve regeneration following its delivery…”
Get full text

Fabrication and characterization of poly-(ε)-caprolactone and bioactive glass composites for tissue engineering applications by Mohammadkhah, Ali, Marquardt, Laura M., Sakiyama-Elbert, Shelly E., Day, Delbert E., Harkins, Amy B.

“…Much work has focused on developing synthetic materials that have tailored degradation profiles and physical properties that may prove useful in developing…”
Get full text

Student award winner in the undergraduate's degree category for the Society for Biomaterials 35th Annual Meeting, Orlando, Florida, April 13-16, 2011. Neurite growth in PEG gels: effect of mechanical stiffness and laminin concentration by Marquardt, Laura, Willits, Rebecca Kuntz

“…Within a 3D environment, the chemical and mechanical properties of a scaffold can significantly influence nerve behavior. How these properties influence with…”
Get full text

Abstract 6955: Activation of ERK pathway by mutant Ras oncoproteins derived from THP-1 cell exosomes by Hwang, Joseph B., Marquardt, Laura, Sait, Osama, Gilliam, Brooke, Xiao, Qiang

“…The study of exosomes has attracted worldwide research due to its ability to modulate cellular activities, especially in the progression of cancer. Exosomes…”
Get full text

Screening for Amblyogenic Factors in a Rural State: Implementing a Statewide Childhood Vision Project by Kemp, Joshua J., Westlake, Laura Lea Marquardt, Christensen, Rebecca D., MacLean, William E.

“…[...]given their location in population centers throughout the state, they provide readily accessible developmental screening services for the entire…”
Get full text

Neurite growth in PEG gels: Effect of mechanical stiffness and laminin concentration by MARQUARDT, Laura, KUNTZ WILLITS, Rebecca

Get full text

Characterization of poly(ethylene glycol) gels with added collagen for neural tissue engineering by Scott, Rebecca, Marquardt, Laura, Willits, Rebecca Kuntz

“…Over the past decade, it has been increasingly recognized that both chemical and mechanical properties of scaffolds influence neural cell behavior, ranging…”
Get full text

Student award winner in the undergraduate's degree category for the society for biomaterials 35th annual meeting, Orlando, Florida, April 13-16, 2011 by Marquardt, Laura, Willits, Rebecca Kuntz

“…Within a 3D environment, the chemical and mechanical properties of a scaffold can significantly influence nerve behavior. How these properties influence with…”
Get full text

Comparison of Conventional, Revascularized, and Bioengineered Methods of Recurrent Laryngeal Nerve Reconstruction by Sand, Jordan P, Park, Andrea M, Bhatt, Neel, Desai, Shaun C, Marquardt, Laura, Sakiyama-Elbert, Shelly, Paniello, Randal C

“…Damage to the recurrent laryngeal nerve (RLN) is highly detrimental to voice, swallow, and cough. The optimal method for reconstitution of a nerve gap after…”
Get more information