Search Results - "Marnell, Christopher S."

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease by Marnell, Christopher S., Bick, Alexander, Natarajan, Pradeep

“…Clonal hematopoiesis of indeterminate potential (CHIP) is the presence of a clonally expanded hematopoietic stem cell caused by a leukemogenic mutation in…”
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B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors by Maachani, Uday B., Tosi, Umberto, Pisapia, David J., Mukherjee, Sushmita, Marnell, Christopher S., Voronina, Julia, Martinez, Daniel, Santi, Mariarita, Dahmane, Nadia, Zhou, Zhiping, Hawkins, Cynthia, Souweidane, Mark M.

“…B7–H3 (CD276), a member of the B7 superfamily, is an important factor in downregulating immune responses against tumors. It is also aberrantly expressed in…”
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Advances in Molecular Imaging of Locally Delivered Targeted Therapeutics for Central Nervous System Tumors by Tosi, Umberto, Marnell, Christopher S, Chang, Raymond, Cho, William C, Ting, Richard, Maachani, Uday B, Souweidane, Mark M

“…Thanks to the recent advances in the development of chemotherapeutics, the morbidity and mortality of many cancers has decreased significantly. However,…”
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Real-Time, in Vivo Correlation of Molecular Structure with Drug Distribution in the Brain Striatum Following Convection Enhanced Delivery by Tosi, Umberto, Kommidi, Harikrishna, Bellat, Vanessa, Marnell, Christopher S, Guo, Hua, Adeuyan, Oluwaseyi, Schweitzer, Melanie E, Chen, Nandi, Su, Taojunfeng, Zhang, Guoan, Maachani, Uday B, Pisapia, David J, Law, Benedict, Souweidane, Mark M, Ting, Richard

“…The blood-brain barrier (BBB) represents a major obstacle in delivering therapeutics to brain lesions. Convection-enhanced delivery (CED), a method that…”
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The PreOp Program: Intensive Preclinical Surgical Exposure is Associated With Increased Medical Student Surgical Interest and Competency by Lazow, Stefanie P., Venn, Rachael A., Lubor, Brienne, Kocharian, Gary, Kreines, Fabiana M., Gilbert, Elizabeth, Marnell, Christopher S., Cricco-Lizza, Eliza, Cooley, Victoria, Christos, Paul, Dakin, Gregory F.

“…As medical students' interest in surgical fields wanes, we investigated the impact of a preclinical surgical exposure program on students’ attitudes toward…”
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18 F-Radiolabeled Panobinostat Allows for Positron Emission Tomography Guided Delivery of a Histone Deacetylase Inhibitor by Kommidi, Harikrishna, Tosi, Umberto, Maachani, Uday B, Guo, Hua, Marnell, Christopher S, Law, Benedict, Souweidane, Mark M, Ting, Richard

“…Histone deacetylase (HDAC) inhibition is becoming an increasingly popular approach to treat cancer, as HDAC overexpression is common in many malignancies. The…”
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18F‑Radiolabeled Panobinostat Allows for Positron Emission Tomography Guided Delivery of a Histone Deacetylase Inhibitor by Kommidi, Harikrishna, Tosi, Umberto, Maachani, Uday B, Guo, Hua, Marnell, Christopher S, Law, Benedict, Souweidane, Mark M, Ting, Richard

“…Histone deacetylase (HDAC) inhibition is becoming an increasingly popular approach to treat cancer, as HDAC overexpression is common in many malignancies. The…”
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Abstract 11843: Population Effects of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD: A Cohort Study in the UK Biobank by Marnell, Christopher S, Bhattacharya, Romit, Zekevat, Seyedeh M, Trinder, Mark, Honigberg, Michael, Peloso, Gina, Natarajan, Pradeep

“…BackgroundModifiable clinical risk factors are estimated to account for the majority of population attributable risk (PAR) for first myocardial infarction…”
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