Search Results - "Marmorstein, R"
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Writers and readers of histone acetylation: structure, mechanism, and inhibition
Published in Cold Spring Harbor perspectives in biology (01-07-2014)“…Histone acetylation marks are written by histone acetyltransferases (HATs) and read by bromodomains (BrDs), and less commonly by other protein modules. These…”
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Longitudinal Associations Between Alcohol Problems and Depressive Symptoms: Early Adolescence Through Early Adulthood
Published in Alcoholism, clinical and experimental research (01-01-2009)“…Background: Alcohol use‐related problems and depressive symptoms are clearly associated with each other, but results regarding the nature of this association…”
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3
Investigating associations between caffeinated beverage consumption and later alcohol consumption among early adolescents
Published in Addictive behaviors (01-03-2019)“…Previous research has demonstrated that caffeinated beverage consumption predicts alcohol consumption among early adolescents. This study aimed to investigate…”
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4
Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design
Published in Oncogene (13-08-2007)“…The post-translational modification of histones plays an important role in chromatin regulation, a process that insures the fidelity of gene expression and…”
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5
Obesity and depression in adolescence and beyond: reciprocal risks
Published in International Journal of Obesity (01-07-2014)“…Objective: Obesity and major depressive disorder (MDD) are associated, but evidence about how they relate over time is conflicting. The goal of this study was…”
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6
Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases
Published in Biochemical Society transactions (01-12-2004)“…The yeast Sir2 (silent information regulator-2) protein functions as an NAD(+)-dependent histone deacetylase to silence gene expression from the mating-type…”
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7
Energy drink consumption and later alcohol use among early adolescents
Published in Addictive behaviors (01-04-2015)“…Abstract Introduction Little is known about the association between energy drink and other substance use in early adolescence despite the fact that the…”
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8
Structure and function of histone acetyltransferases
Published in Cellular and molecular life sciences : CMLS (01-05-2001)“…Histone acetyltranferase (HAT) enzymes are the catalytic subunit of large multisubunit HAT complexes that acetylate the epsilon-amino group of specific lysine…”
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9
Relationships between anxiety and externalizing disorders in youth: the influences of age and gender
Published in Journal of anxiety disorders (01-01-2007)“…Abstract Minimal information about the relationship between anxiety disorders and externalizing disorders in youth is available. This study examined…”
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10
Long-term effects of child abuse and neglect on alcohol use and excessive drinking in middle adulthood
Published in Journal of studies on alcohol and drugs (01-05-2007)“…The purpose of this study was to determine the long-term effects of child abuse and neglect on alcohol use in middle adulthood. Individuals with documented…”
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11
Longitudinal associations between depression and substance dependence from adolescence through early adulthood
Published in Drug and alcohol dependence (01-03-2010)“…Abstract Aims The association between depression and substance dependence is poorly understood; examinations of these two disorders over time during key…”
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In Vitro Activity Assays for MYST Histone Acetyltransferases and Adaptation for High-Throughput Inhibitor Screening
Published in Methods in enzymology (2016)“…Lysine acetylation is a posttranslational modification that is carried out by acetyltransferases. The MYST proteins form the largest and most diverse family of…”
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13
Alcohol and illicit drug dependence among parents: associations with offspring externalizing disorders
Published in Psychological medicine (01-01-2009)“…Previous research indicates that alcohol and drug dependence constitute aspects of a general vulnerability to externalizing disorders that accounts for much of…”
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14
Crystal structure of a p53 core tetramer bound to DNA
Published in Oncogene (22-01-2009)“…The tumor suppressor p53 regulates downstream genes in response to many cellular stresses and is frequently mutated in human cancers. Here, we report the use…”
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Structural Basis for Nicotinamide Cleavage and ADP-Ribose Transfer by NAD+-Dependent Sir2 Histone/Protein Deacetylases
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-2004)“…Sir2 enzymes are broadly conserved from bacteria to humans and have been implicated to play roles in gene silencing, DNA repair, genome stability, longevity,…”
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Interactions Between Internalizing Symptoms and Urgency in the Prediction of Alcohol Use and Expectancies Among Low-Income, Minority Early Adolescents
Published in Substance abuse : research and treatment (01-01-2015)“…This study examined whether urgency, a disposition to rash action under conditions of strong emotion, moderates associations between internalizing symptoms and…”
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17
Major depression and conduct disorder in youth: associations with parental psychopathology and parent-child conflict
Published in Journal of child psychology and psychiatry (01-02-2004)“…Background: This study examined conduct disorder (CD) and major depression (MDD) in adolescents in relationship to parent–child conflict and psychopathology…”
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18
Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
Published in Proceedings of the National Academy of Sciences - PNAS (14-02-2006)“…The SWIRM domain is a module found in the Swi3 and Rsc8 subunits of SWI/SNF-family chromatin remodeling complexes, and the Ada2 and BHC110/LSD1 subunits of…”
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19
Sleep patterns and problems among early adolescents: Associations with alcohol use
Published in Addictive behaviors (01-03-2017)“…Abstract Introduction: Sleep and sleep-related problems are associated with alcohol use and related problems among adults. However, existing research on…”
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20
Psychiatric Disorders Among Offspring of Depressed Mothers: Associations With Paternal Psychopathology
Published in The American journal of psychiatry (01-09-2004)“…OBJECTIVE: The association between maternal depression and offspring dysfunction is well documented; however, little attention has been paid to psychopathology…”
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