Search Results - "Marminon, Christelle"

Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles by Kita, Diogo Henrique, Guragossian, Nathalie, Zattoni, Ingrid Fatima, Moure, Vivian Rotuno, Rego, Fabiane Gomes de Moraes, Lusvarghi, Sabrina, Moulenat, Thomas, Belhani, Billel, Picheth, Geraldo, Bouacida, Sofiane, Bouaziz, Zouhair, Marminon, Christelle, Berredjem, Malika, Jose, Joachim, Gonçalves, Marcos Brown, Ambudkar, Suresh V., Valdameri, Glaucio, Le Borgne, Marc

“…The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR)…”
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Microwave-accelerated multicomponent synthesis and X-ray characterization of novel benzothiadiazinone dioxide derivatives, analogues of Monastrol by Bouzina, Abdeslem, Berredjem, Malika, Belhani, Billel, Bouacida, Sofiane, Marminon, Christelle, Le Borgne, Marc, Bouaziz, Zouhair, Aissaoui, Mohamed

“…We demonstrate here a rapid and comfortable synthetic sequence to benzothiadiazinone dioxide (six-membered cyclic sulfamide) derivatives, analogues of…”
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QSAR Model of Indeno[1,2- b ]indole Derivatives and Identification of N -isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3- b ]furan-3-carboxamide as a Potent CK2 Inhibitor by Haidar, Samer, Marminon, Christelle, Aichele, Dagmar, Nacereddine, Abdelhamid, Zeinyeh, Wael, Bouzina, Abdeslem, Berredjem, Malika, Ettouati, Laurent, Bouaziz, Zouhair, Le Borgne, Marc, Jose, Joachim

“…Casein kinase II (CK2) is an intensively studied enzyme, involved in different diseases, cancer in particular. Different scaffolds were used to develop…”
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Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor by El-Awaad, Ehab, Birus, Robin, Marminon, Christelle, Bouaziz, Zouhair, Ballentin, Laurens, Aichele, Dagmar, Le Borgne, Marc, Jose, Joachim

“…Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive…”
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Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates by Bouzina, Abdeslem, Bechlem, Khaoula, Berredjem, Hajira, Belhani, Billel, Becheker, Imène, Lebreton, Jacques, Le Borgne, Marc, Bouaziz, Zouhair, Marminon, Christelle, Berredjem, Malika

“…Several new sulfamidocarbonyloxyphosphonates were prepared in two steps, namely carbamoylation and sulfamoylation, by using chlorosulfonyl isocyanate (CSI),…”
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Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining by Haidar, Samer, Bouaziz, Zouhair, Marminon, Christelle, Laitinen, Tuomo, Poso, Antti, Le Borgne, Marc, Jose, Joachim

“…Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular…”
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Formulation and Investigation of CK2 Inhibitor-Loaded Alginate Microbeads with Different Excipients by Papp, Boglárka, Le Borgne, Marc, Perret, Florent, Marminon, Christelle, Józsa, Liza, Pető, Ágota, Kósa, Dóra, Nagy, Lajos, Kéki, Sándor, Ujhelyi, Zoltán, Pallér, Ádám, Budai, István, Bácskay, Ildikó, Fehér, Pálma

“…The aim of this study was to formulate and characterize CK2 inhibitor-loaded alginate microbeads via the polymerization method. Different excipients were used…”
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Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds by Bloch, Sylwia, Nejman-Faleńczyk, Bożena, Pierzynowska, Karolina, Piotrowska, Ewa, Węgrzyn, Alicja, Marminon, Christelle, Bouaziz, Zouhair, Nebois, Pascal, Jose, Joachim, Le Borgne, Marc, Saso, Luciano, Węgrzyn, Grzegorz

“…Oxidative stress may be the major cause of induction of Shiga toxin-converting (Stx) prophages from chromosomes of Shiga toxin-producing Escherichia coli…”
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Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α by Hochscherf, Jennifer, Lindenblatt, Dirk, Witulski, Benedict, Birus, Robin, Aichele, Dagmar, Marminon, Christelle, Bouaziz, Zouhair, Le Borgne, Marc, Jose, Joachim, Niefind, Karsten

“…Protein kinase CK2, a member of the eukaryotic protein kinase superfamily, is associated with cancer and other human pathologies and thus an attractive drug…”
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Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures by Lindenblatt, Dirk, Nickelsen, Anna, Applegate, Violetta M, Hochscherf, Jennifer, Witulski, Benedict, Bouaziz, Zouhair, Marminon, Christelle, Bretner, Maria, Le Borgne, Marc, Jose, Joachim, Niefind, Karsten

“…CK2α and CK2α′ are the two isoforms of the catalytic subunit of human protein kinase CK2, an important target for cancer therapy. They have similar, albeit not…”
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Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7 by Nacereddine, Abdelhamid, Bollacke, Andre, Róka, Eszter, Marminon, Christelle, Bouaziz, Zouhair, Fenyvesi, Ferenc, Bácskay, Ildikó Katalin, Jose, Joachim, Perret, Florent, Le Borgne, Marc

“…Since the approval of imatinib in 2001, kinase inhibitors have revolutionized cancer therapies. Inside this family of phosphotransferases, casein kinase 2…”
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Synthesis of N-benzylated indole-, indazole- and benzotriazole-4,7-diones by Marminon, Christelle, Gentili, Jacques, Barret, Roland, Nebois, Pascal

“…The benzylation of 4,7-dimethoxy-1 H-indole ( 5) followed by an oxidative demethylation led to 1-benzyl-1 H-indole-4,7-dione ( 2) with a 73% overall yield…”
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Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors by Marminon, Christelle, Anizon, Fabrice, Moreau, Pascale, Pfeiffer, Bruno, Pierré, Alain, Golsteyn, Roy M, Peixoto, Paul, Hildebrand, Marie-Paule, David-Cordonnier, Marie-Hélène, Lozach, Olivier, Meijer, Laurent, Prudhomme, Michelle

“…Rebeccamycin is an indolocarbazole class inhibitor of topoisomerase I. In the course of structure-activity relationship studies on rebeccamycin derivatives, we…”
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Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion by Bouzina, Abdeslem, Berredjem, Malika, Nocentini, Alessio, Bua, Silvia, Bouaziz, Zouhair, Jose, Joachim, Le Borgne, Marc, Marminon, Christelle, Gratteri, Paola, Supuran, Claudiu T.

“…Ninhydrins show extensive application in organic chemistry and agriculture whereas they have been poorly investigated as bioactive molecules for medicinal…”
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Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design by Goracci, Laura, Nurisso, Alessandra, Roussel, Emile, Pérès, Basile, Chaptal, Vincent, Falson, Pierre, Marminon, Christelle, Jose, Joachim, Le Borgne, Marc, Boumendjel, Ahcène

“…Human breast cancer resistance protein (BCRP), known also as ABCG2, plays a major role in multiple drug resistance (MDR) in tumor cells. Through this ABC…”
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Novel N-acylsulfamoyl-oxazolidin-2ones: Synthesis, antitumor activity, X-ray crystallographic study, molecular docking and POM analyses by Bechlem, Khawla, Berredjem, Malika, Djouad, Seif Eddine, Sothea, Tan Ouk, Bouacida, Sofiane, Marminon, Christelle, Hadda, Taibi Ben, Lebreton, Jaques, Bouzina, Abdeslem

“…•Seven derivatives of novel N-acylsulfamoyl-oxazolidin-2ones were synthesized.•The structures of the new compounds were confirmed using spectroscopy and…”
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Synthesis, In silico study (DFT, ADMET) and crystal structures of novel sulfamoyloxy-oxazolidinones: Interaction with SARS-CoV-2 by Bouzina, Abdeslem, Berredjem, Malika, Bouacida, Sofiane, Bachari, Khaldoun, Marminon, Christelle, Borgne, Marc Le, Bouaziz, Zouhair, Bouone, Yousra Ouafa

“…A new series of sulfamoyloxyoxazolidinone (SOO) derivatives have been synthesized and characterized by single-crystal X-ray diffraction, NMR, IR, MS and EA…”
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Synthesis, in silico study (DFT, ADMET) and crystal structure of novel sulfamoyloxy-oxazolidinones: Interaction with SARS-CoV-2 by Bouzina, Abdeslem, Berredjem, Malika, Bouacida, Sofiane, Bachari, Khaldoun, Marminon, Christelle, Borgne, Marc Le, Bouaziz, Zouhair, Bouone, Yousra Ouafa

“…•10 derivatives of novel sulfamoyloxy-oxazolidinones were designed and synthesized.•The structure of the new compounds was confirmed using spectroscopy and…”
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Novel α-sulfamidophosphonate analogues of fotemustine: efficient synthesis using ultrasound under solvent-free conditions by Guerfi, Meriem, Berredjem, Malika, Bouzina, Abdeslem, Ben Hadda, Taibi, Marminon, Christelle, Otmane Rachedi, Khadidja

“…The development of new clean and effective processes for the preparation of new elaborated compounds is currently an important research axis in organic…”
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Efficient synthesis, crystallographic study, antimicrobial activity and in silico studies of novel bioactive α-aminophosphonates based on pyridine moiety by Grib, Ismahene, Berredjem, Malika, Djouad, Seif-Eddine, Benzaid, Chahrazed, Rachedi, Khadidja Otmane, Bahadi, Rania, Djendi, Lina Manel, Ibrahim-Ouali, Malika, Bouacida, Sofiane, Bachari, Khaldoun, Laichi, Yacine, Marminon, Christelle, Borgne, Marc LE, Bouasla, Radia

“…•Seven derivatives of novel α-aminophosphonates were synthesized under green conditions.•The crystal structure of compound 3g has been elucidated, revealing…”
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