Search Results - "Marley, Anna E."

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet by Bjursell, Mikael, Admyre, Therése, Göransson, Melker, Marley, Anna E, Smith, David M, Oscarsson, Jan, Bohlooly-Y, Mohammad

“…Free fatty acid receptor 2 (Ffar2), also known as GPR43, is activated by short-chain fatty acids (SCFA) and expressed in intestine, adipocytes, and immune…”
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Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells by Watson, Maria L, Macrae, Katherine, Marley, Anna E, Hundal, Harinder S

“…Sustained exposure of pancreatic β cells to an increase in saturated fatty acids induces pleiotropic effects on β-cell function, including a reduction in…”
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The long-chain fatty acid receptor, GPR40, and glucolipotoxicity: investigations using GPR40-knockout mice by Brownlie, Ruth, Mayers, Rachel M, Pierce, Jackie A, Marley, Anna E, Smith, David M

“…GPR40 (G-protein-coupled receptor 40) has been shown to be a physiologically relevant receptor for long-chain fatty acids. It is a family A G-protein-coupled…”
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The Use of Antibodies in Small-Molecule Drug Discovery by Marsden, Catherine J, Eckersley, Sonia, Hebditch, Max, Kvist, Alexander J, Milner, Roy, Mitchell, Danielle, Warwicker, Juli, Marley, Anna E

“…Antibodies are powerful research tools that can be used in many areas of biology to probe, measure, and perturb various biological structures. Successful drug…”
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Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase by Sullivan, Jane E., Brocklehurst, Katy J., Marley, Anna E., Carey, Frank, Carling, David, Beri, Raj K.

“…In vivo, hormone-sensitive lipase (HSL) is known to be phosphorylated on two sites termed the regulatory and basal sites. However, the intracellular role of…”
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Biochemical characterization and deletion analysis of recombinant human protein phosphatase 2C alpha by Marley, A E, Sullivan, J E, Carling, D, Abbott, W M, Smith, G J, Taylor, I W, Carey, F, Beri, R K

“…The use of protein phosphatase inhibitors has been instrumental in defining the intracellular roles of protein phosphatase 1 (PP1), PP2A and PP2B…”
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The cloning expression and tissue distribution of human PP2Cβ by Marley, Anna E., Kline, Adam, Crabtree, Garry, Sullivan, Jane E., Beri, Raj K.

“…We have cloned a novel PP2Cβ isoform from a human liver cDNA library which codes for a protein homologous to other mammalian PP2Cβs at the N-terminus but with…”
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The cloning expression and tissue distribution of human PP2Cβ 1 by Marley, Anna E., Kline, Adam, Crabtree, Garry, Sullivan, Jane E., Beri, Raj K.

“…We have cloned a novel PP2Cβ isoform from a human liver cDNA library which codes for a protein homologous to other mammalian PP2Cβs at the N‐terminus but with…”
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Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase by Beri, Raj K., Marley, Anna E., See, Chee Gee, Sopwith, William F., Aguan, Kripa, Carling, David, Scott, James, Carey, Frank

“…A cDNA encoding rat liver AMP-activated protein kinase (AMPK) was used to isolate human skeletal muscle AMPK cDNA clones. Human AMPK cDNA is more than 90%…”
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