Search Results - "Marlatt, Michael W"

Running throughout middle‐age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice by Marlatt, Michael W., Potter, Michelle C., Lucassen, Paul J., van Praag, Henriette

“…Age‐related memory loss is considered to commence at middle‐age and coincides with reduced adult hippocampal neurogenesis and neurotrophin levels. Consistent…”
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Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition by Lucassen, Paul, Hoozemans, Jeroen, van Haastert, Elise S., Aronica, Eleonora, Bauer, Jan, Marlatt, Michael W., Joels, Marian

“…Microglia and astrocytes contribute to Alzheimer’s disease (AD) etiology and may mediate early neuroinflammatory responses. Despite their possible role in…”
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Distinct structural plasticity in the hippocampus and amygdala of the middle-aged common marmoset ( Callithrix jacchus) by Marlatt, Michael W., Philippens, Ingrid, Manders, Erik, Czéh, Boldizsár, Joels, Marian, Krugers, Harm, Lucassen, Paul J.

“…Adult neurogenesis in the primate brain is generally accepted to occur primarily in two specific areas; the subgranular zone (SGZ) of the hippocampal dentate…”
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Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice by Marlatt, Michael W, Lucassen, Paul J, van Praag, Henriette

“…Abstract Hippocampal neurogenesis can be regulated by extrinsic factors, such as exercise and antidepressants. While there is evidence that the selective…”
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Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer's disease by Marlatt, Michael W, Potter, Michelle C, Bayer, Thomas A, van Praag, Henriette, Lucassen, Paul J

“…Reductions in adult neurogenesis have been documented in the original 3xTg mouse model of Alzheimer's disease (AD), notably occurring at the same age when…”
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Presenilin mouse and zebrafish models for dementia: focus on neurogenesis by van Tijn, Paula, Kamphuis, Willem, Marlatt, Michael W, Hol, Elly M, Lucassen, Paul J

“…Autosomal dominant mutations in the presenilin gene PSEN cause familial Alzheimer's disease (AD), a neurological disorder pathologically characterized by…”
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Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies by Marlatt, Michael W, Lucassen, Paul J, Perry, George, Smith, Mark A, Zhu, Xiongwei

“…Many lines of independent research have provided convergent evidence regarding oxidative stress, cerebrovascular disease, dementia, and Alzheimer's disease…”
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Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine by McCampbell, Alexander, Wessner, Keith, Marlatt, Michael W, Wolffe, Carrie, Toolan, Dawn, Podtelezhnikov, Alexei, Yeh, Suzie, Zhang, Rena, Szczerba, Peter, Tanis, Keith Q, Majercak, John, Ray, William J, Savage, Mary

“…J. Neurochem. (2011) 116, 82-92. ABSTRACT: Elevated plasma homocysteine, a risk factor for Alzheimer's disease, could result from increased production from…”
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Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease by Clark, Timothy A, Lee, Hyun Pil, Rolston, Raj K, Zhu, Xiongwei, Marlatt, Michael W, Castellani, Rudy J, Nunomura, Akihiko, Casadesus, Gemma, Smith, Mark A, Lee, Hyoung-Gon, Perry, George

“…Oxidative imbalance is one of the earliest manifestations of Alzheimer disease (AD) actually preceding the classic pathology of amyloid β deposits and…”
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The cell cycle in Alzheimer disease: A unique target for neuropharmacology by Webber, Kate M., Raina, Arun K., Marlatt, Michael W., Zhu, Xiongwei, Prat, María I., Morelli, Laura, Casadesus, Gemma, Perry, George, Smith, Mark A.

“…Several hypotheses have been proposed attempting to explain the pathogenesis of Alzheimer disease including, among others, theories involving amyloid…”
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Estrogen Bows to a New Master: The Role of Gonadotropins in Alzheimer Pathogenesis by WEBBER, KATE M., CASADESUS, GEMMA, MARLATT, MICHAEL W., PERRY, GEORGE, HAMLIN, CLIVE R., ATWOOD, CRAIG S., BOWEN, RICHARD L., SMITH, MARK A.

“…: Epidemiological data showing a predisposition of women to develop Alzheimer disease (AD) led many researchers to investigate the role of sex steroids, namely…”
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Therapeutic opportunities in Alzheimer disease: one for all or all for one? by Marlatt, Michael W, Webber, Kate M, Moreira, Paula I, Lee, Hyoung-gon, Casadesus, Gemma, Honda, Kazuhiro, Zhu, Xiongwei, Perry, George, Smith, Mark A

“…In recent years, Alzheimer disease (AD) has received great attention as an incurable and fatal disease that threatens the lives of aging individuals. Debates…”
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The Application of Microarray Technology to Neuropathology: Cutting Edge Tool With Clinical Diagnostics Potential or Too Much Information? by McShea, Andrew, Marlatt, Michael W, Lee, Hyoung-gon, Tarkowsky, Stephanie M, Smit, Mariya, Smith, Mark A

“…Microarray technology is a tremendously powerful method for simultaneously monitoring the expression of thousands of species of nucleic acids, usually cellular…”
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Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35 by Kaminsky, Yury G., Marlatt, Michael W., Smith, Mark A., Kosenko, Elena A.

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Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice: Exercise and the Brain by MARLATT, Michael W, LUCASSEN, Paul J, VAN PRAAG, Henriette

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Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ 25–35 by Kaminsky, Yury G., Marlatt, Michael W., Smith, Mark A., Kosenko, Elena A.

“…Amyloid-β peptide (Aβ) is a central player in the pathogenesis and diagnosis of Alzheimer disease. It aggregates to form the core of Alzheimer…”
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Subcellular and metabolic examination of amyloid- beta peptides in Alzheimer disease pathogenesis: Evidence for A beta sub(25-35) by Kaminsky, Yury G, Marlatt, Michael W, Smith, Mark A, Kosenko, Elena A

“…Amyloid- beta peptide (A beta ) is a central player in the pathogenesis and diagnosis of Alzheimer disease. It aggregates to form the core of Alzheimer…”
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Induction of Alzheimer’s-like changes in brain of mice expressing mutant APP fed excess methionine: Methionine diet and Aβ elevation by McCampbell, Alexander, Wessner, Keith, Marlatt, Michael W., Wolffe, Carrie, Toolan, Dawn, Podtelezhnikov, Alexei, Yeh, Suzie, Zhang, Rena, Szczerba, Peter, Tanis, Keith Q., Majercak, John, Ray, William J., Savage, Mary

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Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25-35 by KAMINSKY, Yury G, MARLATT, Michael W, SMITH, Mark A, KOSENKO, Elena A

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Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25-35) by Kaminsky, Yury G, Marlatt, Michael W, Smith, Mark A, Kosenko, Elena A

“…Amyloid-beta peptide (Abeta) is a central player in the pathogenesis and diagnosis of Alzheimer disease. It aggregates to form the core of Alzheimer…”
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