Search Results - "Marland, Jamie R. K."

Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome by Marland, Jamie R K, Smillie, Karen J, Cousin, Michael A

“…Down syndrome (DS) is the most common genetic cause of intellectual disability, and arises from trisomy of human chromosome 21. Accumulating evidence from…”
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In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension by Gray, Mark E, Marland, Jamie R K, Dunare, Camelia, Blair, Ewen O, Meehan, James, Tsiamis, Andreas, Kunkler, Ian H, Murray, Alan F, Argyle, David, Dyson, Alex, Singer, Mervyn, Potter, Mark A

“…Recent advances in the fields of electronics and microfabrication techniques have led to the development of implantable medical devices for use within the…”
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Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin‐II levels by Kokotos, Alexandros C., Harper, Callista B., Marland, Jamie R.K., Smillie, Karen J., Cousin, Michael A., Gordon, Sarah L.

“…The two most abundant molecules on synaptic vesicles (SVs) are synaptophysin and synaptobrevin‐II (sybII). SybII is essential for SV fusion, whereas…”
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Ovine Pulmonary Adenocarcinoma: A Unique Model to Improve Lung Cancer Research by Gray, Mark E, Meehan, James, Sullivan, Paul, Marland, Jamie R K, Greenhalgh, Stephen N, Gregson, Rachael, Clutton, Richard Eddie, Ward, Carol, Cousens, Chris, Griffiths, David J, Murray, Alan, Argyle, David

“…Lung cancer represents a major worldwide health concern; although advances in patient management have improved outcomes for some patients, overall 5-year…”
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Predicting Cardiovascular Stent Complications Using Self‐Reporting Biosensors for Noninvasive Detection of Disease by Hoare, Daniel, Tsiamis, Andreas, Marland, Jamie R. K., Czyzewski, Jakub, Kirimi, Mahmut T., Holsgrove, Michael, Russell, Ewan, Neale, Steven L., Mirzai, Nosrat, Mitra, Srinjoy, Mercer, John R.

“…Self‐reporting implantable medical devices are the future of cardiovascular healthcare. Cardiovascular complications such as blocked arteries that lead to the…”
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ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons by Eva, Richard, Crisp, Sarah, Marland, Jamie R K, Norman, Jim C, Kanamarlapudi, Venkateswarlu, ffrench-Constant, Charles, Fawcett, James W

“…Integrins are involved in axon growth and regeneration. Manipulation of integrins is a route to promoting axon regeneration and understanding regeneration…”
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Post-Operative Monitoring of Intestinal Tissue Oxygenation Using an Implantable Microfabricated Oxygen Sensor by Marland, Jamie R K, Gray, Mark E, Argyle, David J, Underwood, Ian, Murray, Alan F, Potter, Mark A

“…Anastomotic leakage (AL) is a common and dangerous post-operative complication following intestinal resection, causing substantial morbidity and mortality…”
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A Novel Translational Ovine Pulmonary Adenocarcinoma Model for Human Lung Cancer by Gray, Mark E, Sullivan, Paul, Marland, Jamie R K, Greenhalgh, Stephen N, Meehan, James, Gregson, Rachael, Clutton, R Eddie, Cousens, Chris, Griffiths, David J, Murray, Alan, Argyle, David

“…cell line and murine models have historically dominated pre-clinical cancer research. These models can be expensive and time consuming and lead to only a small…”
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Toward Synthetic Vascular Graft Monitoring Using a Flip-Chip-on-Flex Impedance Spectroscopy Sensor by Marland, Jamie R. K., Tsiamis, Andreas, Hoare, Daniel, Lopez, Pablo G. Ledesma, Neale, Steven L., Mercer, John R., Mitra, Srinjoy

“…Synthetic vascular grafts are used in a wide range of clinical applications. However, they can become prone to occlusion over time, due to the growth of…”
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Synaptic vesicle exocytosis and increased cytosolic calcium are both necessary but not sufficient for activity‐dependent bulk endocytosis by Morton, Andrew, Marland, Jamie R. K., Cousin, Michael A.

“…Activity‐dependent bulk endocytosis (ADBE) is the dominant synaptic vesicle (SV) endocytosis mode in central nerve terminals during intense neuronal activity…”
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In vivo application of an implantable tri-anchored methylene blue-based electrochemical pH sensor by González-Fernández, Eva, Staderini, Matteo, Marland, Jamie R.K., Gray, Mark E., Uçar, Ahmet, Dunare, Camelia, Blair, Ewen O., Sullivan, Paul, Tsiamis, Andreas, Greenhalgh, Stephen N., Gregson, Rachael, Clutton, Richard Eddie, Smith, Stewart, Terry, Jonathan G., Argyle, David J., Walton, Anthony J., Mount, Andrew R., Bradley, Mark, Murray, Alan F.

“…The development of robust implantable sensors is important in the successful advancement of personalised medicine as they have the potential to provide in situ…”
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Predictive and Diagnostic Biomarkers of Anastomotic Leakage: A Precision Medicine Approach for Colorectal Cancer Patients by Gray, Mark, Marland, Jamie R. K., Murray, Alan F., Argyle, David J., Potter, Mark A.

“…Development of an anastomotic leak (AL) following intestinal surgery for the treatment of colorectal cancers is a life-threatening complication. Failure of the…”
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Comparison of Conventional and Maskless Lithographic Techniques for More than Moore Post-Processing of Foundry CMOS Chips by Tsiamis, Andreas, Li, Yifan, Dunare, Camelia, Marland, Jamie R. K., Blair, Ewen O., Smith, Stewart, Terry, Jonathan G., Mitra, Srinjoy, Underwood, Ian, Murray, Alan F., Walton, Anthony J.

“…This article details and compares the technology options for post-processing foundry produced CMOS at chip-scale to enable More than Moore functionality. In…”
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Biocompatibility of common implantable sensor materials in a tumor xenograft model by Gray, Mark E., Meehan, James, Blair, Ewen O., Ward, Carol, Langdon, Simon P., Morrison, Linda R., Marland, Jamie R. K., Tsiamis, Andreas, Kunkler, Ian H., Murray, Alan, Argyle, David

“…Real‐time monitoring of tumor microenvironment parameters using an implanted biosensor could provide valuable information on the dynamic nature of a tumor's…”
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Application of Greek cross structures for process development of electrochemical sensors by Zhang, Minxing, Zhang, Shan, Dunare, Camelia, Marland, Jamie R. K., Terry, Jonathan G, Smith, Stewart

“…Using a test structure chip designed to assist in process development for reference electrode fabrication for integrated electrochemical sensors, this paper…”
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Nanog retrotransposed genes with functionally conserved open reading frames by Robertson, Morag, Stenhouse, Frances, Colby, Douglas, Marland, Jamie R K, Nichols, Jennifer, Tweedie, Susan, Chambers, Ian

“…The Nanog gene plays a key role in the pluripotency of early embryonic cells in vitro and in vivo. In this article retrotransposed copies of Nanog, termed…”
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Optimization of Nafion Polymer Electrolyte Membrane Design and Microfabrication by Marland, Jamie R. K., Moore, Fiona, Dunare, Camelia, Tsiamis, Andreas, Gonzalez-Fernandez, Eva, Blair, Ewen O., Smith, Stewart, Terry, Jonathan G., Murray, Alan F., Walton, Anthony J.

“…Nafion is a solid electrolyte polymer that can be used as a sensor membrane in microfabricated electrochemical oxygen sensors. It allows ions to be transported…”
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Predicting Cardiovascular Stent Complications Using Self‐Reporting Biosensors for Noninvasive Detection of Disease (Adv. Sci. 15/2022) by Hoare, Daniel, Tsiamis, Andreas, Marland, Jamie R. K., Czyzewski, Jakub, Kirimi, Mahmut T., Holsgrove, Michael, Russell, Ewan, Neale, Steven L., Mirzai, Nosrat, Mitra, Srinjoy, Mercer, John R.

“…Self‐Reporting Biosensors In article number 2105285, John R. Mercer and co‐workers develop an implantable miniaturised sensor and telemetry system that can…”
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An Impedance Sensor for Pathologically Relevant Detection of In-Stent Restenosis In Vitro by Hoare, Daniel, Fisher, Simon, Nelson, Finlay, Tsiamis, Andreas, Marland, Jamie R. K., Mitra, Srinjoy, Neale, Steve L., Mercer, John R.

“…Cardiovascular disease (CVD) is the biggest cause of death globally. CVD is caused by atherosclerosis which is the accumulation of fatty deposits, often within…”
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Development and Validation of a Numerical Model for Miniature Electrochemical Oxygen Sensors by Zhang, Shan, Schmuser, Ilka, Marland, Jamie R.K., Underwood, Ian

“…In this study, a numerical simulation model was developed in COMSOL 6.0 and applied to a miniature electrochemical oxygen sensor. The purpose of this…”
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