Search Results - "Markus Hartl"

amica: an interactive and user-friendly web-platform for the analysis of proteomics data by Didusch, Sebastian, Madern, Moritz, Hartl, Markus, Baccarini, Manuela

“…Quantitative proteomics has become an increasingly prominent tool in the study of life sciences. A substantial hurdle for many biologists are, however, the…”
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A Unique Family of Neuronal Signaling Proteins Implicated in Oncogenesis and Tumor Suppression by Hartl, Markus, Schneider, Rainer

“…The neuronal proteins GAP43 (neuromodulin), MARCKS, and BASP1 are highly expressed in the growth cones of nerve cells where they are involved in signal…”
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B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma by Griss, Johannes, Bauer, Wolfgang, Wagner, Christine, Simon, Martin, Chen, Minyi, Grabmeier-Pfistershammer, Katharina, Maurer-Granofszky, Margarita, Roka, Florian, Penz, Thomas, Bock, Christoph, Zhang, Gao, Herlyn, Meenhard, Glatz, Katharina, Läubli, Heinz, Mertz, Kirsten D., Petzelbauer, Peter, Wiesner, Thomas, Hartl, Markus, Pickl, Winfried F., Somasundaram, Rajasekharan, Steinberger, Peter, Wagner, Stephan N.

“…Tumor associated inflammation predicts response to immune checkpoint blockade in human melanoma. Current theories on regulation of inflammation center on…”
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A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription by Platanitis, Ekaterini, Demiroz, Duygu, Schneller, Anja, Fischer, Katrin, Capelle, Christophe, Hartl, Markus, Gossenreiter, Thomas, Müller, Mathias, Novatchkova, Maria, Decker, Thomas

“…Cells maintain the balance between homeostasis and inflammation by adapting and integrating the activity of intracellular signaling cascades, including the…”
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FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates by Turco, Eleonora, Witt, Marie, Abert, Christine, Bock-Bierbaum, Tobias, Su, Ming-Yuan, Trapannone, Riccardo, Sztacho, Martin, Danieli, Alberto, Shi, Xiaoshan, Zaffagnini, Gabriele, Gamper, Annamaria, Schuschnig, Martina, Fracchiolla, Dorotea, Bernklau, Daniel, Romanov, Julia, Hartl, Markus, Hurley, James H., Daumke, Oliver, Martens, Sascha

“…The autophagy cargo receptor p62 facilitates the condensation of misfolded, ubiquitin-positive proteins and their degradation by autophagy, but the molecular…”
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Strategies to target the cancer driver MYC in tumor cells by Weber, Leonie I, Hartl, Markus

“…The MYC oncoprotein functions as a master regulator of cellular transcription and executes non-transcriptional tasks relevant to DNA replication and cell cycle…”
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Efficient Access to 3′-Terminal Azide-Modified RNA for Inverse Click-Labeling Patterns by Santner, Tobias, Hartl, Markus, Bister, Klaus, Micura, Ronald

“…Labeled RNA becomes increasingly important for molecular diagnostics and biophysical studies on RNA with its diverse interaction partners, which range from…”
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Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis by Hartl, Markus, Füßl, Magdalena, Boersema, Paul J, Jost, Jan‐Oliver, Kramer, Katharina, Bakirbas, Ahmet, Sindlinger, Julia, Plöchinger, Magdalena, Leister, Dario, Uhrig, Glen, Moorhead, Greg BG, Cox, Jürgen, Salvucci, Michael E, Schwarzer, Dirk, Mann, Matthias, Finkemeier, Iris

“…Histone deacetylases have central functions in regulating stress defenses and development in plants. However, the knowledge about the deacetylase functions is…”
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Jasmonoyl-l-Isoleucine Coordinates Metabolic Networks Required for Anthesis and Floral Attractant Emission in Wild Tobacco (Nicotiana attenuata) by Stitz, Michael, Hartl, Markus, Baldwin, Ian T., Gaquerel, Emmanuel

“…Jasmonic acid and its derivatives Gasmonates [JAs]) play central roles in floral development and maturation. The binding of jasmonoyl-l-isoleucine (JA-IIe) to…”
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The brain acid‐soluble protein 1 (BASP1) interferes with the oncogenic capacity of MYC and its binding to calmodulin by Hartl, Markus, Puglisi, Kane, Nist, Andrea, Raffeiner, Philipp, Bister, Klaus

“…The MYC protein is a transcription factor with oncogenic potential controlling fundamental cellular processes such as cell proliferation, metabolism,…”
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Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase by Schenk, Sven, Bannister, Stephanie C, Sedlazeck, Fritz J, Anrather, Dorothea, Minh, Bui Quang, Bileck, Andrea, Hartl, Markus, von Haeseler, Arndt, Gerner, Christopher, Raible, Florian, Tessmar-Raible, Kristin

“…Many marine animals, ranging from corals to fishes, synchronise reproduction to lunar cycles. In the annelid this timing is orchestrated by an endogenous…”
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Redox Regulation of Arabidopsis Mitochondrial Citrate Synthase by Schmidtmann, Elisabeth, König, Ann-Christine, Orwat, Anne, Leister, Dario, Hartl, Markus, Finkemeier, Iris

“…Citrate synthase has a key role in the tricarboxylic （TCA） cycle of mitochondria of all organisms, as it cata- lyzes the first committed step which is the…”
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Inhibitor of MYC identified in a Kröhnke pyridine library by Hart, Jonathan R., Garner, Amanda L., Yu, Jing, Ito, Yoshihiro, Sun, Minghao, Ueno, Lynn, Rhee, Jin-Kyu, Baksh, Michael M., Stefan, Eduard, Hartl, Markus, Bister, Klaus, Vogt, Peter K., Janda, Kim D.

“…In a fluorescence polarization screen for the MYC–MAX interaction, we have identified a novel small-molecule inhibitor of MYC, KJ-Pyr-9, from a Kröhnke…”
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The mitochondrial lysine acetylome of Arabidopsis by König, Ann-Christine, Hartl, Markus, Boersema, Paul J, Mann, Matthias, Finkemeier, Iris

“…Posttranslational modifications are essential regulators of protein functions as they can modify enzyme activities or protein-molecule interactions by changing…”
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Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex by Velkova, Maria, Silva, Nicola, Dello Stritto, Maria Rosaria, Schleiffer, Alexander, Barraud, Pierre, Hartl, Markus, Jantsch, Verena

“…Homologous recombination is a high-fidelity repair pathway for DNA double-strand breaks employed during both mitotic and meiotic cell divisions. Such repair…”
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The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response by Asanović, Igor, Strandback, Emilia, Kroupova, Alena, Pasajlic, Djurdja, Meinhart, Anton, Tsung-Pin, Pai, Djokovic, Nemanja, Anrather, Dorothea, Schuetz, Thomas, Suskiewicz, Marcin Józef, Sillamaa, Sirelin, Köcher, Thomas, Beveridge, Rebecca, Nikolic, Katarina, Schleiffer, Alexander, Jinek, Martin, Hartl, Markus, Clausen, Tim, Penninger, Josef, Macheroux, Peter, Weitzer, Stefan, Martinez, Javier

“…The tRNA ligase complex (tRNA-LC) splices precursor tRNAs (pre-tRNA), and Xbp1-mRNA during the unfolded protein response (UPR). In aerobic conditions, a…”
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The Diarylheptanoid Curcumin Induces MYC Inhibition and Cross-Links This Oncoprotein to the Coactivator TRRAP by Mödlhammer, Alexander, Pfurtscheller, Sandra, Feichtner, Andreas, Hartl, Markus, Schneider, Rainer

“…The c-Myc protein (MYC) is a transcription factor with strong oncogenic potential controlling fundamental cellular processes. In most human tumors, MYC is…”
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The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra by Ziegler, Berenice, Yiallouros, Irene, Trageser, Benjamin, Kumar, Sumit, Mercker, Moritz, Kling, Svenja, Fath, Maike, Warnken, Uwe, Schnölzer, Martina, Holstein, Thomas W, Hartl, Markus, Marciniak-Czochra, Anna, Stetefeld, Jörg, Stöcker, Walter, Özbek, Suat

“…The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or…”
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Inosine induces context-dependent recoding and translational stalling by Licht, Konstantin, Hartl, Markus, Amman, Fabian, Anrather, Dorothea, Janisiw, Michael P, Jantsch, Michael F

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Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra by Hartl, Markus, Mitterstiller, Anna-Maria, Valovka, Taras, Breuker, Kathrin, Hobmayer, Bert, Bister, Klaus

“…The c-myc protooncogene encodes a transcription factor (Myc) with oncogenic potential. Myc and its dimerization partner Max are bHLH-Zip DNA binding proteins…”
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