Search Results - "Markus, R."

Lipidomics: New Tools and Applications by Wenk, Markus R.

“…Once viewed simply as a reservoir for carbon storage, lipids are no longer cast as bystanders in the drama of biological systems. The emerging field of…”
Get full text

Intermolecular Olefin Functionalisation Involving Aryl Radicals Generated from Arenediazonium Salts by Heinrich, Markus R.

“…This minireview is aimed at giving an overview of recent advances in olefin functionalisation reactions involving aryl radicals generated from arenediazonium…”
Get full text

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response by Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter

“…Recent studies suggest that the sterol metabolic network participates in the interferon (IFN) antiviral response. However, the molecular mechanisms linking IFN…”
Get full text

New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics by Meyer, Markus R.

“…This review article covers English-written and PubMed-listed review articles and original studies published between January 2015 and April 2016 dealing with…”
Get full text

Molecular and cellular dynamics of the 26S proteasome by Sakata, Eri, Eisele, Markus R., Baumeister, Wolfgang

“…In eukaryotic cells, the ubiquitin-proteasome system serves to remove proteins that are either dysfunctional or no longer needed. The 26S proteasome is a 2.5…”
Get full text

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid by Nguyen, Long N., Ma, Dongliang, Shui, Guanghou, Wong, Peiyan, Cazenave-Gassiot, Amaury, Zhang, Xiaodong, Wenk, Markus R., Goh, Eyleen L. K., Silver, David L.

“…Mfsd2a is the major transporter of the omega-3 fatty acid docosahexaenoic acid (DHA) into brain, with Mfsd2a -knockout mice showing reduced DHA in brain,…”
Get full text

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts by Chung, Jeeyun, Torta, Federico, Masai, Kaori, Lucast, Louise, Czapla, Heather, Tanner, Lukas B., Narayanaswamy, Pradeep, Wenk, Markus R., Nakatsu, Fubito, De Camilli, Pietro

“…Lipid transfer between cell membrane bilayers at contacts between the endoplasmic reticulum (ER) and other membranes help to maintain membrane lipid…”
Get full text

Sphingolipid metabolism during Toll‐like receptor 4 (TLR4)‐mediated macrophage activation by Olona, Antoni, Hateley, Charlotte, Muralidharan, Sneha, Wenk, Markus R., Torta, Federico, Behmoaras, Jacques

“…Macrophage activation in response to stimulation of Toll‐like receptor 4 (TLR4) provides a paradigm for investigating energy metabolism that regulates the…”
Get full text

Base-Induced Radical Carboamination of Nonactivated Alkenes with Aryldiazonium Salts by Kindt, Stephanie, Wicht, Karina, Heinrich, Markus R.

“…A new transition-metal-free version of the Meerwein arylation has been developed. The key feature of this carboamination-type reaction is the slow…”
Get full text

Thermally Induced Carbohydroxylation of Styrenes with Aryldiazonium Salts by Kindt, Stephanie, Wicht, Karina, Heinrich, Markus R.

“…The radical carbohydroxylation of styrenes with aryldiazonium salts has been achieved under mild thermal conditions. A broad range of aryldiazonium salts was…”
Get full text

Translating IL-6 biology into effective treatments by Choy, Ernest H., De Benedetti, Fabrizio, Takeuchi, Tsutomu, Hashizume, Misato, John, Markus R., Kishimoto, Tadamitsu

“…In 1973, IL-6 was identified as a soluble factor that is secreted by T cells and is important for antibody production by B cells. Since its discovery more than…”
Get full text

The emerging field of lipidomics by Wenk, Markus R

“…The crucial role of lipids in cell, tissue and organ physiology is demonstrated by a large number of genetic studies and by many human diseases that involve…”
Get full text

Shifted Selectivity in Protonation Enables the Mild Deuteration of Arenes Through Catalytic Amounts of Bronsted Acids in Deuterated Methanol by Fischer, Oliver, Hubert, Anja, Heinrich, Markus R

“…Taking advantage of the “differentiating effect” of the solvent methanol, deuterations of electron-rich aromatic systems can be carried out under mild acid…”
Get full text

Recommendations for good practice in MS-based lipidomics by Köfeler, Harald C., Ahrends, Robert, Baker, Erin S., Ekroos, Kim, Han, Xianlin, Hoffmann, Nils, Holčapek, Michal, Wenk, Markus R., Liebisch, Gerhard

“…In the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new…”
Get full text

Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli by Busch, Markus R., Rajendran, Chitra, Sterner, Reinhard

“…We present a detailed structure–function analysis of the ureidoacrylate amidohydrolase RutB from Eschericha coli, which is an essential enzyme of the Rut…”
Get full text

Extensive characterization of human tear fluid collected using different techniques unravels the presence of novel lipid amphiphiles by Lam, Sin Man, Tong, Louis, Duan, Xinrui, Petznick, Andrea, Wenk, Markus R, Shui, Guanghou

“…The tear film covers the anterior eye and the precise balance of its various constituting components is critical for maintaining ocular health. The composition…”
Get full text

The Membrane Stress Response Buffers Lethal Effects of Lipid Disequilibrium by Reprogramming the Protein Homeostasis Network by Thibault, Guillaume, Shui, Guanghou, Kim, Woong, McAlister, Graeme C., Ismail, Nurzian, Gygi, Steven P., Wenk, Markus R., Ng, Davis T.W.

“…Lipid composition can differ widely among organelles and even between leaflets of a membrane. Lipid homeostasis is critical because disequilibrium can have…”
Get full text

OpenSimRoot: widening the scope and application of root architectural models by Postma, Johannes A., Kuppe, Christian, Owen, Markus R., Mellor, Nathan, Griffiths, Marcus, Bennett, Malcolm J., Lynch, Jonathan P., Watt, Michelle

“…OpenSimRoot is an open-source, functional–structural plant model and mathematical description of root growth and function. We describe OpenSimRoot and its…”
Get full text

Oxidative Radical Arylation of Anilines with Arylhydrazines and Dioxygen from Air by Hofmann, Josefa, Jasch, Hannelore, Heinrich, Markus R

“…Substituted 2-aminobiphenyls have been prepared from arylhydrazine hydrochlorides and anilines in biphasic radical arylation reactions with dioxygen from air…”
Get full text

Metal-Free Organic Dyes for Dye-Sensitized Solar Cells: From Structure: Property Relationships to Design Rules by Mishra, Amaresh, Fischer, Markus K.R, Bäuerle, Peter

“…Works without ruthenium as well: Dye-sensitized solar cells (DSSCs) incorporating metal-free organic dyes have been considerably improved in recent years…”
Get full text