Search Results - "Marks, William J"

Pallidal versus Subthalamic Deep-Brain Stimulation for Parkinson's Disease by Follett, Kenneth A, Weaver, Frances M, Stern, Matthew, Hur, Kwan, Harris, Crystal L, Luo, Ping, Marks, William J, Rothlind, Johannes, Sagher, Oren, Moy, Claudia, Pahwa, Rajesh, Burchiel, Kim, Hogarth, Penelope, Lai, Eugene C, Duda, John E, Holloway, Kathryn, Samii, Ali, Horn, Stacy, Bronstein, Jeff M, Stoner, Gatana, Starr, Philip A, Simpson, Richard, Baltuch, Gordon, De Salles, Antonio, Huang, Grant D, Reda, Domenic J

“…In this randomized trial of deep-brain stimulation targeted to either the globus pallidus interna or the subthalamic nucleus in patients with advanced…”
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Cost-Effectiveness of Deep Brain Stimulation for Advanced Parkinson's Disease in the United States by Pietzsch, Jan B, Garner, Abigail M, Marks, Jr, William J

“…Deep brain stimulation (DBS), which uses an implantable device to modulate brain activity, is clinically superior to medical therapy for treating advanced…”
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Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial by Marks, William J, MD, Bartus, Raymond T, PhD, Siffert, Joao, MD, Davis, Charles S, PhD, Lozano, Andres, MD, Boulis, Nicholas, MD, Vitek, Jerrold, MD, Stacy, Mark, MD, Turner, Dennis, MD, Verhagen, Leonard, MD, Bakay, Roy, MD, Watts, Raymond, MD, Guthrie, Barton, MD, Jankovic, Joseph, MD, Simpson, Richard, MD, Tagliati, Michele, MD, Alterman, Ron, MD, Stern, Matthew, MD, Baltuch, Gordon, MD, Starr, Philip A, MD, Larson, Paul S, MD, Ostrem, Jill L, MD, Nutt, John, MD, Kieburtz, Karl, MD, Kordower, Jeffrey H, PhD, Olanow, C Warren, Dr

“…Summary Background In an open-label phase 1 trial, gene delivery of the trophic factor neurturin via an adeno-associated type-2 vector (AAV2) was well…”
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Regional alterations of brain microstructure in Parkinson's disease using diffusion tensor imaging by Zhan, Wang, Kang, Gail A., Glass, Graham A., Zhang, Yu, Shirley, Cheryl, Millin, Rachel, Possin, Katherine L., Nezamzadeh, Marzieh, Weiner, Michael W., Marks Jr, William J., Schuff, Norbert

“…This study tested the hypothesis that diffusion tensor imaging can detect alteration in microscopic integrity of white matter and basal ganglia regions known…”
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Differential effects of deep brain stimulation target on motor subtypes in Parkinson's disease by Katz, Maya, Luciano, Marta San, Carlson, Kimberly, Luo, Ping, Marks Jr, William J., Larson, Paul S., Starr, Philip A., Follett, Kenneth A., Weaver, Frances M., Stern, Matthew B., Reda, Domenic J., Ostrem, Jill L.

“…Objective The Veterans Administration Cooperative Studies Program #468, a multicenter study that randomized Parkinson's disease (PD) patients to either…”
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Analytical and clinical validity of wearable, multi-sensor technology for assessment of motor function in patients with Parkinson’s disease in Japan by Oyama, Genko, Burq, Maximilien, Hatano, Taku, Marks, William J., Kapur, Ritu, Fernandez, Jovelle, Fujikawa, Keita, Furusawa, Yoshihiko, Nakatome, Keisuke, Rainaldi, Erin, Chen, Chen, Ho, King Chung, Ogawa, Takashi, Kamo, Hikaru, Oji, Yutaka, Takeshige-Amano, Haruka, Taniguchi, Daisuke, Nakamura, Ryota, Sasaki, Fuyuko, Ueno, Shinichi, Shiina, Kenta, Hattori, Anri, Nishikawa, Noriko, Ishiguro, Mayu, Saiki, Shinji, Hayashi, Ayako, Motohashi, Masatoshi, Hattori, Nobutaka

“…Continuous, objective monitoring of motor signs and symptoms may help improve tracking of disease progression and treatment response in Parkinson’s disease…”
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Wrist-worn sensor-based measurements for drug effect detection with small samples in people with Lewy Body Dementia by Chen, Chen, Kowahl, Nathan R., Rainaldi, Erin, Burq, Maximilien, Munsie, Leanne M., Battioui, Chakib, Wang, Jian, Biglan, Kevin, Marks, William J., Kapur, Ritu

“…Few late-stage clinical trials in Parkinson's disease (PD) have produced evidence on the clinical validity of sensor-based digital measurements of daily life…”
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Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial by Marks, William J, MD, Ostrem, Jill L, MD, Verhagen, Leonard, MD, Starr, Philip A, MD, Larson, Paul S, MD, Bakay, Roy AE, MD, Taylor, Robin, MSN, Cahn-Weiner, Deborah A, PhD, Stoessl, A Jon, MD, Olanow, C Warren, MD, Bartus, Raymond T, PhD

“…Summary Background There is an urgent need for therapies that slow or reverse the progression of Parkinson's disease (PD). Neurotrophic factors can improve the…”
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Virtual exam for Parkinson’s disease enables frequent and reliable remote measurements of motor function by Burq, Maximilien, Rainaldi, Erin, Ho, King Chung, Chen, Chen, Bloem, Bastiaan R., Evers, Luc J. W., Helmich, Rick C., Myers, Lance, Marks, William J., Kapur, Ritu

“…Sensor-based remote monitoring could help better track Parkinson’s disease (PD) progression, and measure patients’ response to putative disease-modifying…”
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Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome) by Ostrem, Jill L., Marks Jr, William J., Volz, Monica M., Heath, Susan L., Starr, Philip A.

“…Idiopathic cranial–cervical dystonia (ICCD) is an adult‐onset dystonia syndrome affecting orbicularis oculi, facial, oromandibular, and cervical musculature…”
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Inclusion and exclusion criteria for DBS in dystonia by Bronte-Stewart, Helen, Taira, Takaomi, Valldeoriola, Francesc, Merello, Marcello, Marks Jr, William J., Albanese, Alberto, Bressman, Susan, Moro, and Elena

“…When considering a patient with dystonia for deep brain stimulation (DBS) surgery several factors need to be considered. Level B evidence has shown that all…”
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Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease: A Randomized Controlled Trial by Weaver, Frances M, Follett, Kenneth, Stern, Matthew, Hur, Kwan, Harris, Crystal, Marks, William J, Rothlind, Johannes, Sagher, Oren, Reda, Domenic, Moy, Claudia S, Pahwa, Rajesh, Burchiel, Kim, Hogarth, Penelope, Lai, Eugene C, Duda, John E, Holloway, Kathryn, Samii, Ali, Horn, Stacy, Bronstein, Jeff, Stoner, Gatana, Heemskerk, Jill, Huang, Grant D, CSP 468 Study Group, for the

“…CONTEXT Deep brain stimulation is an accepted treatment for advanced Parkinson disease (PD), although there are few randomized trials comparing treatments, and…”
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Long-Term Safety of Patients with Parkinson's Disease Receiving rAAV2-Neurturin (CERE-120) Gene Transfer by Marks, Jr, William J, Baumann, Tiffany L, Bartus, Raymond T

“…The objective of this study was to assess the long-term safety of surgically administered recombinant adeno-associated virus serotype-2 (rAAV2)-neurturin…”
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Measuring Physical Functioning Using Wearable Sensors in Parkinson Disease and Chronic Obstructive Pulmonary Disease (the Accuracy of Digital Assessment of Performance Trial Study): Protocol for a Prospective Observational Study by de Graaf, Debbie, de Vries, Nienke M, van de Zande, Tessa, Schimmel, Janneke J P, Shin, Sooyoon, Kowahl, Nathan, Barman, Poulami, Kapur, Ritu, Marks, Jr, William J, van 't Hul, Alex, Bloem, Bastiaan

“…Physical capacity and physical activity are important aspects of physical functioning and quality of life in people with a chronic disease such as Parkinson…”
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New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures by Boxer, Adam L., Gold, Michael, Feldman, Howard, Boeve, Bradley F., Dickinson, Susan L.-J., Fillit, Howard, Ho, Carole, Paul, Robert, Pearlman, Rodney, Sutherland, Margaret, Verma, Ajay, Arneric, Stephen P., Alexander, Brian M., Dickerson, Bradford C., Dorsey, Earl Ray, Grossman, Murray, Huey, Edward D., Irizarry, Michael C., Marks, William J., Masellis, Mario, McFarland, Frances, Niehoff, Debra, Onyike, Chiadi U., Paganoni, Sabrina, Panzara, Michael A., Rockwood, Kenneth, Rohrer, Jonathan D., Rosen, Howard, Schuck, Robert N., Soares, Holly D., Tatton, Nadine

“…Introduction Frontotemporal lobar degeneration (FTLD) is the most common form of dementia for those under 60 years of age. Increasing numbers of therapeutics…”
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Induction of bradykinesia with pallidal deep brain stimulation in patients with cranial-cervical dystonia by Berman, Brian D, Starr, Philip A, Marks, Jr, William J, Ostrem, Jill L

“…Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is an effective and well-tolerated treatment for idiopathic generalized dystonia. More…”
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Spontaneous Pallidal Neuronal Activity in Human Dystonia: Comparison With Parkinson's Disease and Normal Macaque by Starr, Philip A, Rau, Geoff M, Davis, Valerie, Marks, William J., Jr, Ostrem, Jill L, Simmons, Donn, Lindsey, Nadja, Turner, Robert S

“…1 Departments of Neurological Surgery, 2 Neurology, and 3 Nursing, University of California, San Francisco; and 4 Parkinson’s Disease Research, Education, and…”
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Toward a Mobile Platform for Real-world Digital Measurement of Depression: User-Centered Design, Data Quality, and Behavioral and Clinical Modeling by Nickels, Stefanie, Edwards, Matthew D, Poole, Sarah F, Winter, Dale, Gronsbell, Jessica, Rozenkrants, Bella, Miller, David P, Fleck, Mathias, McLean, Alan, Peterson, Bret, Chen, Yuanwei, Hwang, Alan, Rust-Smith, David, Brant, Arthur, Campbell, Andrew, Chen, Chen, Walter, Collin, Arean, Patricia A, Hsin, Honor, Myers, Lance J, Marks Jr, William J, Mega, Jessica L, Schlosser, Danielle A, Conrad, Andrew J, Califf, Robert M, Fromer, Menachem

“…Background Although effective mental health treatments exist, the ability to match individuals to optimal treatments is poor, and timely assessment of response…”
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Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease by Rowland, Nathan C., Starr, Philip A., Larson, Paul S., Ostrem, Jill L., Marks Jr, William J., Lim, Daniel A.

“…Cell transplantation and gene therapy each show promise to enhance the treatment of Parkinson's disease (PD). However, because cell transplantation and gene…”
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Shorter Disease Duration Correlates With Improved Long-term Deep Brain Stimulation Outcomes in Young-Onset DYT1 Dystonia by Markun, Leslie C., Starr, Philip A., Air, Ellen L., Marks, William J., Volz, Monica M., Ostrem, Jill L.

“…Abstract BACKGROUND: Treatment with deep brain stimulation (DBS) of the globus pallidus internus in children with DYT1 primary torsion dystonia is highly…”
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