Search Results - "Marks, G S"

Relationship between tissue damage and heme oxygenase expression in chorionic villi of term human placenta by Lash, G E, McLaughlin, B E, MacDonald-Goodfellow, S K, Smith, G N, Brien, J F, Marks, G S, Nakatsu, K, Graham, C H

“…Heme oxygenase (HO) catalyzes the oxidation of heme to carbon monoxide (CO), biliverdin, and iron and is thought to play a role in protecting tissues from…”
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Carbon Monoxide Decreases Perfusion Pressure in Isolated Human Placenta by Bainbridge, S.A, Farley, A.E, McLaughlin, B.E, Graham, C.H, Marks, G.S, Nakatsu, K, Brien, J.F, Smith, G.N

“…Carbon monoxide (CO) is one of the metabolites formed via heme oxidation catalysed by the enzyme heme oxygenase (HO). Endogenous formation of CO, mediated by…”
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Nitric oxide actions in paraventricular nucleus: cardiovascular and neurochemical implications by Horn, T, Smith, P M, McLaughlin, B E, Bauce, L, Marks, G S, Pittman, Q J, Ferguson, A V

“…We have examined potential functions of nitric oxide (NO) within the paraventricular nucleus (PVN) in urethan-anesthetized male Sprague-Dawley rats. Initial…”
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Effects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells by Appleton, S D, Marks, G S, Nakatsu, K, Brien, J F, Smith, G N, Graham, C H, Lash, G E

“…Although hypoxia induces heme oxygenase (HO)-1 protein and mRNA expression in many cell types, hypoxia has also been shown to decrease HO-1 mRNA and protein…”
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Selective Inhibition of Heme Oxygenase, without Inhibition of Nitric Oxide Synthase or Soluble Guanylyl Cyclase, by Metalloporphyrins at Low Concentrations by APPLETON, S. D, CHRETIEN, M. L, MCLAUGHLIN, B. E, VREMAN, H. J, STEVENSON, D. K, BRIEN, J. F, NAKATSU, K, MAURICE, D. H, MARKS, G. S

“…Studies on the physiological role of heme oxygenase (HO) require an inhibitor that will selectively inhibit HO activity without inhibiting the activity of…”
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Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone by Coceani, F., Kelsey, L., Seidlitz, E., Marks, G.S., McLaughlin, B.E., Vreman, H.J., Stevenson, D.K., Rabinovitch, M., Ackerley, C.

“…1 We have previously shown that carbon monoxide (CO) potently relaxes the lamb ductus arteriosus and have ascribed this response to inhibition of a cytochrome…”
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Effect of glucose and oxygen deprivation on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells by Appleton, S D, Lash, G E, Marks, G S, Nakatsu, K, Brien, J F, Smith, G N, Graham, C H

“…Although hypoxia induces heme oxygenase (HO)-1 mRNA and protein expression in many cell types, recent studies in our laboratory using human placental tissue…”
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Heme Oxygenase Activity in Term Human Placenta by McLaughlin, B.E., Hutchinson, J.M., Graham, C.H., Smith, G.N., Marks, G.S., Nakatsu, K., Brien, J.F.

“…Carbon monoxide (CO) is a novel gaseous chemical messenger, formed during heme oxygenase (HO)-catalysed oxidation of heme. CO is proposed to play a key role(s)…”
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Comparison of rat and human cytochrome P450 (CYP) sources of N-alkylprotoporphyrin IX. Formation after interaction with porphyrinogenic xenobiotics: studies with cDNA-expressed single CYP enzymes by Gamble, J. T., Nakatsu, K., Marks, G. S.

“…1. The porphyrinogenicity of certain xenobiotics is due to mechanism-based inactivation of selected cytochrome P450 (CYP) enzymes, with concurrent formation of…”
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Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate by Marks, G S, McLaughlin, B E, Jimmo, S L, Poklewska-Koziell, M, Brien, J F, Nakatsu, K

“…Nitrovasodilators is a term used to describe a diverse group of agents believed to exert their vasodilator effect by a common mechanism, namely formation of…”
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Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation by Odrcich, M.J., Graham, C.H., Kimura, K.A., McLaughlin, B.E., Marks, G.S., Nakatsu, K., Brien, J.F.

“…Nitric oxide (NO) and carbon monoxide (CO) are novel gaseous chemical messengers that play key roles in cell function and cell-cell communication in many organ…”
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An extracellular source of heme can induce a significant heme oxygenase mediated relaxation in the rat aorta by Hosein, S, Marks, G S, Brien, J F, McLaughlin, B E, Nakatsu, K

“…Carbon monoxide has been under active investigation for a role in controlling vascular tone throughout the last decade because of its ability to induce…”
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Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation by Cook, M N, Nakatsu, K, Marks, G S, McLaughlin, B E, Vreman, H J, Stevenson, D K, Brien, J F

“…Rat aorta was homogenized and the 13000 x g supernatant fraction was tested for heme oxygenase (HO) activity by using a sensitive gas chromatographic method to…”
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Haem Oxygenase Activity in Human Umbilical Cord and Rat Vascular Tissues by Vreman, H.J., Wong, R.J., Kim, E.C., Nabseth, D.C., Marks, G.S., Stevenson, D.K.

“…Carbon monoxide (CO) has been shown to affect vascular tone in smooth muscle cells and thus, may regulate regional or systemic blood pressure as well as…”
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What role does the heme-- heme oxygenase--carbon monoxide system play in vasoregulation? by Marks, G S, Brien, J F, Nakatsu, K

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The source of endogenous carbon monoxide formation in human placental chorionic villi by Ahmed, H, McLaughlin, B E, Soong, J, Marks, G S, Brien, J F, Nakatsu, K

“…Carbon monoxide (CO) is proposed to play a role in placental vascular control, as the placenta produces and responds to CO. The mechanism by which CO is formed…”
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The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate by Hussain, A S, Marks, G S, Brien, J F, Nakatsu, K

“…Carbon monoxide (CO), a vasodilator, has been implicated as an activator of soluble guanylyl cyclase (sGC) to effect smooth muscle relaxation; however, this…”
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Endogenous Carbon Monoxide Formation by Chorionic Villi of Term Human Placenta by McLaughlin, B.E., Lash, G.E., Graham, C.H., Smith, G.N., Vreman, H.J., Stevenson, D.K., Marks, G.S., Nakatsu, K., Brien, J.F.

“…Carbon monoxide (CO) is a novel messenger that is proposed to play a complementary role with nitric oxide in the regulation of placental haemodynamics. In a…”
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Heme oxygenase: the physiological role of one of its metabolites, carbon monoxide and interactions with zinc protoporphyrin, cobalt protoporphyrin and other metalloporphyrins by Marks, G S

“…In 1991, we postulated that carbon monoxide, which is formed endogenously from heme catabolism catalyzed by heme oxygenase and shares some of the chemical and…”
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Biotransformation of glyceryl trinitrate occurs concurrently with relaxation of rabbit aorta by Brien, J F, McLaughlin, B E, Breedon, T H, Bennett, B M, Nakatsu, K, Marks, G S

“…This study was conducted to test the hypothesis that biotransformation of glyceryl trinitrate (GTN) is involved in GTN-induced relaxation of vascular smooth…”
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