Search Results - "Markowitz, Arnold"

Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma by Lee, Lik Hang, Cavalcanti, Marcela S, Segal, Neil H, Hechtman, Jaclyn F, Weiser, Martin R, Smith, J Joshua, Garcia-Aguilar, Julio, Sadot, Eran, Ntiamoah, Peter, Markowitz, Arnold J, Shike, Moshe, Stadler, Zsofia K, Vakiani, Efsevia, Klimstra, David S, Shia, Jinru

“…Immune checkpoint blockade targeting the programmed death-1 (PD-1) pathway has shown efficacy in several types of cancers including mismatch-repair-deficient…”
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S462 Long-Term Oncologic Outcomes in Patients With History of Non-Colorectal Cancer and Positive Multi-Target Stool DNA Test With Negative Diagnostic Colonoscopy for Advanced Colorectal Neoplasia by Patel, Swati, Yoo, Jin Woo, Schattner, Mark A., Markowitz, Arnold J., Mendelsohn, Robin B.

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Mismatch Repair-Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy by Cercek, Andrea, Dos Santos Fernandes, Gustavo, Roxburgh, Campbell S, Ganesh, Karuna, Ng, Shu, Sanchez-Vega, Francisco, Yaeger, Rona, Segal, Neil H, Reidy-Lagunes, Diane L, Varghese, Anna M, Markowitz, Arnold, Wu, Chao, Szeglin, Bryan, Sauvé, Charles-Etienne Gabriel, Salo-Mullen, Erin, Tran, Christina, Patel, Zalak, Krishnan, Asha, Tkachuk, Kaitlyn, Nash, Garrett M, Guillem, Jose, Paty, Philip B, Shia, Jinru, Schultz, Nikolaus, Garcia-Aguilar, Julio, Diaz, Luis A, Goodman, Karyn, Saltz, Leonard B, Weiser, Martin R, Smith, J Joshua, Stadler, Zsofia K

“…Evaluate response of mismatch repair-deficient (dMMR) rectal cancer to neoadjuvant chemotherapy. dMMR rectal tumors at Memorial Sloan Kettering Cancer Center…”
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Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma by Latham, Alicia, Shia, Jinru, Patel, Zalak, Reidy-Lagunes, Diane L, Segal, Neil H, Yaeger, Rona, Ganesh, Karuna, Connell, Louise, Kemeny, Nancy E, Kelsen, David P, Hechtman, Jaclyn F, Nash, Garrett M, Paty, Philip B, Zehir, Ahmet, Tkachuk, Kaitlin A, Sheikh, Rania, Markowitz, Arnold J, Mandelker, Diana, Offit, Kenneth, Berger, Michael F, Cercek, Andrea, Garcia-Aguilar, Julio, Saltz, Leonard B, Weiser, Martin R, Stadler, Zsofia K

“…The prevalence and clinical characteristics of small bowel adenocarcinomas (SBA) in the setting of Lynch syndrome have not been well studied. We characterized…”
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Indications for Total Gastrectomy in CDH1 Mutation Carriers and Outcomes of Risk-Reducing Minimally Invasive and Open Gastrectomies by Vos, Elvira L, Salo-Mullen, Erin E, Tang, Laura H, Schattner, Mark, Yoon, Sam S, Gerdes, Hans, Markowitz, Arnold J, Mandelker, Diana, Janjigian, Yelena, Offitt, Kenneth, Coit, Daniel G, Stadler, Zsofia K, Strong, Vivian E

“…CDH1 variants are increasingly identified on commercially available multigene panel tests, calling for data to inform counseling of individuals without a…”
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Clinical features of young onset colorectal cancer patients from a large cohort at a single cancer center by Park, Leslie, O’Connell, Kelli, Herzog, Keri, Chatila, Walid, Walch, Henry, Palmaira, Randze Lerie D., Cercek, Andrea, Shia, Jinru, Shike, Moshe, Markowitz, Arnold J., Garcia-Aguilar, Julio, Schattner, Mark A., Kantor, Elizabeth D., Du, Mengmeng, Mendelsohn, Robin B.

“…Purpose The aim of this study is to describe the demographics and clinical features of patients with young onset (YO) CRC. Methods A retrospective review of…”
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Role of the industry representative in the practice of gastroenterology and GI endoscopy by Bucobo, Juan Carlos, Kassim, Olufemi, Konijeti, Gauree G., Abraham, Bincy P., Abegunde, Ayokunle T., Farraye, Francis A., Guha, Sushovan, Kowalski, Thomas, Kumar, Anand, Markowitz, Arnold J., Schoeppner, Harald L., Tierney, William M.

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Factors associated with detection of hereditary diffuse gastric cancer on endoscopy in individuals with germline CDH1 mutations by Laszkowska, Monika, Tang, Laura, Vos, Elvira, King, Stephanie, Salo-Mullen, Erin, Magahis, Patrick T., Abate, Miseker, Catchings, Amanda, Zauber, Ann G., Hahn, Anne I., Schattner, Mark, Coit, Daniel, Stadler, Zsofia K., Strong, Vivian E., Markowitz, Arnold J.

“…Individuals with germline pathogenic CDH1 variants have a high risk of hereditary diffuse gastric cancer. The sensitivity of EGD in detecting signet ring cell…”
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Early-onset Colorectal Cancer Patients Do Not Require Shorter Intervals for Post-surgical Surveillance Colonoscopy by Mendelsohn, Robin B., Hahn, Anne I., Palmaira, Randze Lerie, Saxena, Asha R., Mukthinuthalapati, Pavan Kedar, Schattner, Mark A., Markowitz, Arnold J., Ludwig, Emmy, Shah, Pari, Calo, Delia, Gerdes, Hans, Yaeger, Rona, Stadler, Zsofia, Zauber, Ann G., Cercek, Andrea

“…Early-onset colorectal cancer (EO-CRC), diagnosed before age 50, is rising in incidence worldwide. Although post-surgical colonoscopy surveillance strategies…”
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Structure of the Mucosal and Stool Microbiome in Lynch Syndrome by Yan, Yan, Drew, David A., Markowitz, Arnold, Lloyd-Price, Jason, Abu-Ali, Galeb, Nguyen, Long H., Tran, Christina, Chung, Daniel C., Gilpin, Katherine K., Meixell, Dana, Parziale, Melanie, Schuck, Madeline, Patel, Zalak, Richter, James M., Kelsey, Peter B., Garrett, Wendy S., Chan, Andrew T., Stadler, Zsofia K., Huttenhower, Curtis

“…The gut microbiota has been associated with colorectal cancer (CRC), but causal alterations preceding CRC have not been elucidated. To prospectively assess…”
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A Prospective Clinical Trial to Evaluate Mesothelin as a Biomarker for the Clinical Management of Patients with Esophageal Adenocarcinoma by Byun, Alexander J., Grosser, Rachel A., Choe, Jennie K., Rizk, Nabil P., Tang, Laura H., Molena, Daniela, Tan, Kay See, Restle, David, Cheema, Waseem, Zhu, Amy, Gerdes, Hans, Markowitz, Arnold J., Bains, Manjit S., Rusch, Valerie W., Jones, David R., Adusumilli, Prasad S.

“…To investigate the utility of serum soluble mesothelin-related peptide (SMRP) and tumor mesothelin expression in the management of esophageal adenocarcinoma…”
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Clinical Value of CT Colonography Versus Preoperative Colonoscopy in the Surgical Management of Occlusive Colorectal Cancer by Horvat, Natally, Raj, Aradhna, Ward, John M, Smith, J Joshua, Markowitz, Arnold J, Gollub, Marc J

“…CT colonography (CTC) has been recognized as a complementary approach to evaluating the entire colon after incomplete colonoscopy (IC) in patients with…”
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Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade by Harrold, Emily C., Foote, Michael B., Rousseau, Benoit, Walch, Henry, Kemel, Yelena, Richards, Allison L., Keane, Fergus, Cercek, Andrea, Yaeger, Rona, Rathkopf, Dana, Segal, Neil H., Patel, Zalak, Maio, Anna, Borio, Matilde, O’Reilly, Eileen M., Reidy, Diane, Desai, Avni, Janjigian, Yelena Y., Murciano-Goroff, Yonina R., Carlo, Maria I., Latham, Alicia, Liu, Ying L., Walsh, Michael F., Ilson, David, Rosenberg, Jonathan E., Markowitz, Arnold J., Weiser, Martin R., Rossi, Anthony M., Vanderbilt, Chad, Mandelker, Diana, Bandlamudi, Chaitanya, Offit, Kenneth, Berger, Michael F., Solit, David B., Saltz, Leonard, Shia, Jinru, Diaz, Luis A., Stadler, Zsofia K.

“…Metastatic and localized mismatch repair-deficient (dMMR) tumors are exquisitely sensitive to immune checkpoint blockade (ICB). The ability of ICB to prevent…”
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Endoscopic Management of Esophageal Anastomotic Leaks After Surgery for Malignant Disease by Licht, Eugene, MD, Markowitz, Arnold J., MD, Bains, Manjit S., MD, Gerdes, Hans, MD, Ludwig, Emmy, MD, Mendelsohn, Robin B., MD, Rizk, Nabil P., MD, Shah, Pari, MD, Strong, Vivian E., MD, Schattner, Mark A., MD

“…Background Esophageal anastomotic leaks after cancer surgery remain a major cause of morbidity and mortality. Endoscopic interventions, including covered metal…”
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A proposed staging system and stage-specific interventions for familial adenomatous polyposis by Lynch, Patrick M., MD, Morris, Jeffrey S., PhD, Wen, Sijin, PhD, Advani, Shailesh M., MD, MPH, Ross, William, MD, Chang, George J., MD, MS, Rodriguez-Bigas, Miguel, MD, FACS, FASCRS, Raju, Gottumukkala S., MD, FASGE, Ricciardiello, Luigi, MD, Iwama, Takeo, MD, Rossi, Benedito M., MD, PhD, Pellise, Maria, MD, PhD, Stoffel, Elena, MD, MPH, Wise, Paul E., MD, Bertario, Lucio, MD, Saunders, Brian, MD, PRCP, Burt, Randall, MD, Belluzzi, Andrea, MD, Ahnen, Dennis, MD, Matsubara, Nagahide, MD, Bülow, Steffen, MD, DMSc, Jespersen, Niels, MD, Clark, Susan K., MD, FRCS, Erdman, Steven H., MD, Markowitz, Arnold J., MD, Bernstein, Inge, MD, PhD, MHM, De Haas, Niels, MD, Syngal, Sapna, MD, MPH, Moeslein, Gabriela, MD

“…Background and Aims It is not possible to accurately count adenomas in many patients with familial adenomatous polyposis (FAP). Nevertheless, polyp counts are…”
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Early age of onset and broad cancer spectrum persist in MSH6- and PMS2-associated Lynch syndrome by Liu, Ying L., Cadoo, Karen A., Maio, Anna, Patel, Zalak, Kemel, Yelena, Salo-Mullen, Erin, Catchings, Amanda, Ranganathan, Megha, Kane, Sarah, Soslow, Robert, Ceyhan-Birsoy, Ozge, Mandelker, Diana, Carlo, Maria I., Walsh, Michael F., Shia, Jinru, Markowitz, Arnold J., Offit, Kenneth, Stadler, Zsofia K., Latham, Alicia

“…This study aimed to characterize MSH6/PMS2-associated mismatch repair–deficient (MMR-D)/microsatellite instability-high (MSI-H) tumors, given revised…”
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EUS-guided fiducial placement for image-guided radiation therapy in GI malignancies by using a 22-gauge needle (with videos ) by DiMaio, Christopher J., MD, Nagula, Satish, MD, Goodman, Karyn A., MD, Ho, Alice Y., MD, Markowitz, Arnold J., MD, Schattner, Mark A., MD, Gerdes, Hans, MD

“…Background Image-guided radiation therapy (IGRT) is dependent on the presence of fiducial markers for target localization and tracking. EUS-guided placement of…”
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Computed Tomography Colonography vs Colonoscopy for Colorectal Cancer Surveillance After Surgery by Weinberg, David S., Pickhardt, Perry J., Bruining, David H., Edwards, Kristin, Fletcher, Joel G., Gollub, Marc J., Keenan, Eileen M., Kupfer, Sonia S., Li, Tianyu, Lubner, Sam J., Markowitz, Arnold J., Ross, Eric A.

“…Recommendations for surveillance after curative surgery for colorectal cancer (CRC) include a 1-year post-resection abdominal-pelvic computed tomography (CT)…”
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Effectiveness of a surveillance program of upper endoscopy for upper gastrointestinal cancers in Lynch syndrome patients by Ceravolo, Amanda H., Yang, Janie J., Latham, Alicia, Markowitz, Arnold J., Shia, Jinru, Mermelstein, Joe, Calo, Delia, Gerdes, Hans, Ludwig, Emmy, Schattner, Mark A., Stadler, Zsofia K., Kantor, Elizabeth, Du, Mengmeng, Mendelsohn, Robin B.

“…Background and aims Lynch syndrome (LS) is the most common cause of hereditary colorectal cancer and is associated with an increased lifetime risk of gastric…”
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Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas by Liu, Sandy, Gӧnen, Mithat, Stadler, Zsofia K., Weiser, Martin R., Hechtman, Jaclyn F., Vakiani, Efsevia, Wang, Tao, Vyas, Monika, Joneja, Upasana, Al-Bayati, Moataz, Segal, Neil H., Smith, J. Joshua, King, Sarah, Guercio, Shanna, Ntiamoah, Peter, Markowitz, Arnold J., Zhang, Liying, Cercek, Andrea, Garcia-Aguilar, Julio, Saltz, Leonard B., Diaz, Luis A., Klimstra, David S., Shia, Jinru

“…Blockade of the interaction between PD-1 and its ligands PD-L1 has shown clinical efficacy across several tumor types, especially in mismatch-repair-deficient…”
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