Search Results - "Markovitz, Rebecca"

The diversity of the immune response to the A2 domain of human factor VIII by Markovitz, Rebecca C., Healey, John F., Parker, Ernest T., Meeks, Shannon L., Lollar, Pete

“…Approximately 30% of patients with severe hemophilia A develop inhibitory anti–factor VIII (fVIII) antibodies (Abs). We characterized 29 anti-human A2…”
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Expansion of the clinical phenotype of GALE deficiency by Markovitz, Rebecca, Owen, Nichole, Satter, Lisa Forbes, Kirk, Susan, Mahoney, Donald H., Bertuch, Alison A., Scaglia, Fernando

“…Congenital disorders of glycosylation are a group of rare monogenic inborn errors of metabolism caused by defective glycoprotein and glycolipid glycan…”
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GARS‐related disease in infantile spinal muscular atrophy: Implications for diagnosis and treatment by Markovitz, Rebecca, Ghosh, Rajarshi, Kuo, Molly E., Hong, William, Lim, Jaehyung, Bernes, Saunder, Manberg, Stephanie, Crosby, Kathleen, Tanpaiboon, Pranoot, Bharucha‐Goebel, Diana, Bonnemann, Carsten, Mohila, Carrie A., Mizerik, Elizabeth, Woodbury, Suzanne, Bi, Weimin, Lotze, Timothy, Antonellis, Anthony, Xiao, Rui, Potocki, Lorraine

“…The majority of patients with spinal muscular atrophy (SMA) identified to date harbor a biallelic exonic deletion of SMN1. However, there have been reports of…”
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A subset of high-titer anti–factor VIII A2 domain antibodies is responsive to treatment with factor VIII by Eubanks, Joshua, Baldwin, W. Hunter, Markovitz, Rebecca, Parker, Ernest T., Cox, Courtney, Kempton, Christine L., Meeks, Shannon L.

“…The primary B-cell epitopes of factor VIII (fVIII) are in the A2 and C2 domains. Within the C2 domain, antibody epitope and kinetics are more important than…”
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Decreasing the Humoral Response to Factor VIII By Targeted Deletion of Factor VIII - Specific B Cells by Markovitz, Rebecca C., Healey, John F., Baldwin, W. Hunter, Parker, Ernest T., Meeks, Shannon L., Lollar, Pete

“…The development of neutralizing anti-factor VIII (fVIII) antibodies (inhibitors) remains the most significant complication in the treatment of hemophilia A…”
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Reduced Antigenicity Of Ovine Factor VIII In Human Hemophilia A Inhibitor Plasmas by Vanijcharoenkarn, Kristine, Zakas, Philip M, Markovitz, Rebecca, Meeks, Shannon L., Doering, Christopher B

“…Current treatment of hemophilia A is severely limited by the development of anti-fVIII inhibitory antibodies (inhibitors). Several approaches are being pursued…”
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Anti-Factor VIII A2 Epitopes In a Murine Bleeding Model by Eubanks, Joshua, Baldwin, Wallace Hunter, Markovitz, Rebecca, Parker, Ernest T, Meeks, Shannon L.

“…Up to 30% of patients with severe hemophilia A will develop inhibitory antibodies to factor VIII (fVIII inhibitors). In addition, autoimmune antibodies to…”
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B-Cell Epitopes Within The A2 and C2 Domains Of Coagulant Factor VIII Refined By Orthologous Protein Antigenicity by Zakas, Philip M, Vanijcharoenkarn, Kristine, Markovitz, Rebecca, Meeks, Shannon L., Doering, Christopher B

“…Approximately 20-30% of severe hemophilia A patients develop inhibitors (anti-fVIII antibodies) to human fVIII (hfVIII) with the primary targets being the A2…”
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The Structural and Functional Diversity of the Humoral Immune Response to the A2 Domain of Human Factor VIII by Markovitz, Rebecca, Lollar, John (Pete) S., Healey, John F., Parker, Ernest T, Meeks, Shannon

“…Abstract 2247 Hemophilia A is an X-linked recessive disorder that is caused by a deficiency or defect of factor VIII (fVIII) coagulant protein. The major…”
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Distribution of Bim Determines MCL-1 Dependence or Co-Dependence on BCL-xL/BCL-2 In Multiple Myeloma by Boise, Lawrence H., Morales, Alejo A, Kurtoglu, Metin, Matulis, Shannon M, Markovitz, Rebecca, Lee, Kelvin P, Lonial, Sagar

“…Abstract 4054 The inappropriate activation of oncogenes can result in the up-regulation of pro-apoptotic signals often in the form of BH3-only proteins such as…”
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The Complexity of the Humoral Immune Response to Factor VIII in Hemophilia A by Markovitz, Rebecca Claire

“…The humoral immune response is the most serious complication in the treatment of hemophilia A patients. Approximately thirty percent of patients with severe…”
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What did you do to my newspaper? by Markovitz, Rebecca R

“…After college, I spent seven years working as an art director at The Wall Street Journal before moving to Cleveland to join the Crain's team…”
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Summer in the City: ANTIQUING by Markovitz, Rebecca R

“…Another event I was excited to check out last summer was the ever-growing Cleveland Flea, a well-organized and curated "monthly urban treasure hunt," as it is…”
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Expansion of the clinical phenotype of GALE deficiency by Markovitz, Rebecca, Owen, Nichole, Satter, Lisa Forbes, Kirk, Susan, Mahoney, Donald H, Bertuch, Alison A, Scaglia, Fernando

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What did you do to mynewspaper? by Markovitz, Rebecca R

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Summer in the City; ANTIQUING by Markovitz, Rebecca R

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Poetry: Joy by Markovitz, Rebecca

“…POETRY: JOY…”
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