Search Results - "Markov, V. V."
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Symmetric lipophilic polyamines exhibiting antitumor activity
Published in Bioorganic & medicinal chemistry (15-12-2022)“…[Display omitted] Unsymmetric lipophilic polyamine derivatives are considered as potential antitumor agents. Here, a series of novel symmetric lipophilic…”
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2
Soloxolone para -methylanilide effectively suppresses aggressive phenotype of glioblastoma cells including TGF-β1-induced glial-mesenchymal transition in vitro and inhibits growth of U87 glioblastoma xenografts in mice
Published in Frontiers in pharmacology (29-07-2024)“…Soloxolone amides are semisynthetic triterpenoids that can cross the blood-brain barrier and inhibit glioblastoma growth both and . Here we investigate the…”
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3
A new look at the infrared properties of z ∼ 5 galaxies
Published in Monthly notices of the Royal Astronomical Society (01-12-2022)“…ABSTRACT Recent Atacama Large Millimeter Array large surveys unveiled the presence of significant dust continuum emission in star-forming galaxies at z > 4…”
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Modulation of Tumour-Related Signaling Pathways by Natural Pentacyclic Triterpenoids and their Semisynthetic Derivatives
Published in Current medicinal chemistry (01-01-2017)“…Pentacyclic triterpenoids are a large class of natural isoprenoids that are widely biosynthesized in higher plants. These compounds are potent anticancer…”
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Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial
Published in The Lancet (British edition) (04-07-2009)“…Summary Background Rivaroxaban is an oral direct factor Xa inhibitor that has been effective in prevention of venous thromboembolism in patients undergoing…”
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Vladimir Bibikhin: the connoisseur of poetry and the poet
Published in Slovo.ru : Baltiĭskiĭ akt͡s︡ent (2024)“…The publication of «Selected Records from 1965 to 1989» has exposed the reader to poetry of Vladimir Bibikhin’s poetry as a key to understanding the patterns…”
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Neoteny, Prolongation of Youth: From Naked Mole Rats to "Naked Apes" (Humans)
Published in Physiological reviews (01-04-2017)“…It has been suggested that highly social mammals, such as naked mole rats and humans, are long-lived due to neoteny (the prolongation of youth). In both…”
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Origin and evolution of the ligand-binding ability of nuclear receptors
Published in Molecular and cellular endocrinology (01-03-2011)“…The origin of the ligand-binding ability of nuclear receptors is still a matter of discussion. Current opposing models are the early evolution of an ancestral…”
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The Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies
Published in International journal of molecular sciences (10-12-2023)“…Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is partly due to chronic inflammation that accompanies the disease and…”
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A structural signature motif enlightens the origin and diversification of nuclear receptors
Published in PLoS genetics (21-04-2021)“…Nuclear receptors are ligand-activated transcription factors that modulate gene regulatory networks from embryonic development to adult physiology and thus…”
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The Role of DAF-21/Hsp90 in Mouth-Form Plasticity in Pristionchus pacificus
Published in Molecular biology and evolution (01-07-2017)“…Phenotypic plasticity is increasingly recognized to facilitate adaptive change in plants and animals, including insects, nematodes, and vertebrates. Plasticity…”
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A Comparative Study of Different Protocols for Isolation of Murine Neutrophils from Bone Marrow and Spleen
Published in International journal of molecular sciences (08-12-2023)“…Neutrophils are considered as the main player in innate immunity. In the last few years, it has been shown that they are involved in different physiological…”
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Biological rhythms in the deep-sea hydrothermal mussel Bathymodiolus azoricus
Published in Nature communications (10-07-2020)“…Biological rhythms are a fundamental property of life. The deep ocean covers 66% of our planet surface and is one of the largest biomes. The deep sea has long…”
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Textual Criticism of Ostrovsky’s Translations from Latin. Part 2. Plautus’ The Asses and Issues of the Text Source
Published in Dva veka russkoj klassiki (2022)“…The article continues the investigation of textological issues associated with the surviving draft translation of the comoedia palliata The Asses (Asinaria) by…”
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Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo
Published in Pharmaceutics (30-05-2022)“…In this investigation, we extensively studied the mechanism of antitumor activity of bovine pancreatic RNase A. Using confocal microscopy, we show that after…”
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Traceability, reproducibility and wiki-exploration for "à-la-carte" reconstructions of genome-scale metabolic models
Published in PLoS computational biology (01-05-2018)“…Genome-scale metabolic models have become the tool of choice for the global analysis of microorganism metabolism, and their reconstruction has attained high…”
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Soloxolone N -3-(Dimethylamino)propylamide Restores Drug Sensitivity of Tumor Cells with Multidrug-Resistant Phenotype via Inhibition of P-Glycoprotein Efflux Function
Published in Molecules (Basel, Switzerland) (18-10-2024)“…Multidrug resistance (MDR) remains a significant challenge in cancer therapy, primarily due to the overexpression of transmembrane drug transporters, with…”
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Core genes involved in the regulation of acute lung injury and their association with COVID-19 and tumor progression: A bioinformatics and experimental study
Published in PloS one (22-11-2021)“…Acute lung injury (ALI) is a specific form of lung damage caused by different infectious and non-infectious agents, including SARS-CoV-2, leading to severe…”
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Deformation of a Two-Dimensional Trace Pattern of a Detonation Flow with a “Continuous” Change in the Width of a Flat Channel
Published in Doklady. a journal of the Russian Academy of Sciences. Physics (01-08-2023)“…A numerical study of two-dimensional cellular detonation of a hydrogen–air mixture in channels of various widths was carried out, and data were obtained on the…”
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Influence of Combinations of Lipophilic and Phosphate Backbone Modifications on Cellular Uptake of Modified Oligonucleotides
Published in Molecules (Basel, Switzerland) (01-01-2024)“…Numerous types of oligonucleotide modifications have been developed since automated synthesis of DNA/RNA became a common instrument in the creation of…”
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