Search Results - "Markmann, J. F."

Subnormothermic Machine Perfusion for Ex Vivo Preservation and Recovery of the Human Liver for Transplantation by Bruinsma, B. G., Yeh, H., Özer, S., Martins, P. N., Farmer, A., Wu, W., Saeidi, N., Op den Dries, S., Berendsen, T. A., Smith, R. N., Markmann, J. F., Porte, R. J., Yarmush, M. L., Uygun, K., Izamis, M.‐L.

“…To reduce widespread shortages, attempts are made to use more marginal livers for transplantation. Many of these grafts are discarded for fear of inferior…”
Get full text

ASTS Recommended Practice Guidelines for Controlled Donation after Cardiac Death Organ Procurement and Transplantation by Reich, D. J., Mulligan, D. C., Abt, P. L., Pruett, T. L., Abecassis, M. M. I., D’Alessandro, A., Pomfret, E. A., Freeman, R. B., Markmann, J. F., Hanto, D. W., Matas, A. J., Roberts, J. P., Merion, R. M., Klintmalm, G. B. G.

“…The American Society of Transplant Surgeons (ASTS) champions efforts to increase organ donation. Controlled donation after cardiac death (DCD) offers the…”
Get full text

Anti‐CD45RB/Anti‐TIM‐1‐Induced Tolerance Requires Regulatory B Cells by Lee, K. M., Kim, J. I., Stott, R., Soohoo, J., O’Connor, M. R., Yeh, H., Zhao, G., Eliades, P., Fox, C., Cheng, N., Deng, S., Markmann, J. F.

“…The role of B cells in transplant tolerance remains unclear. Although B‐cell depletion often prolongs graft survival, sometimes it results in more rapid…”
Get full text

Human Monoclonal Antibody MBL‐HCV1 Delays HCV Viral Rebound Following Liver Transplantation: A Randomized Controlled Study by Chung, R. T., Gordon, F. D., Curry, M. P., Schiano, T. D., Emre, S., Corey, K., Markmann, J. F., Hertl, M., Pomposelli, J. J., Pomfret, E. A., Florman, S., Schilsky, M., Broering, T. J., Finberg, R. W., Szabo, G., Zamore, P. D., Khettry, U., Babcock, G. J., Ambrosino, D. M., Leav, B., Leney, M., Smith, H. L., Molrine, D. C.

“…Rapid allograft infection complicates liver transplantation (LT) in patients with hepatitis C virus (HCV). Pegylated interferon‐α and ribavirin therapy after…”
Get full text

HCC Patients Suffer Less From Geographic Differences in Organ Availability by Schuetz, C., Dong, N., Smoot, E., Elias, N., Schoenfeld, D. A., Markmann, J. F., Yeh, H.

“…It has been suggested that the number of exception model for end‐stage liver disease (MELD) points for hepatocellular carcinoma (HCC) overestimates mortality…”
Get full text

Transplant Center Volume and Outcomes After Liver Retransplantation by Reese, P. P., Yeh, H., Thomasson, A. M., Shults, J., Markmann, J. F.

“…Liver retransplantation surgery has a high rate of allograft failure due to patient comorbidities and technical demands of the procedure. Success of liver…”
Get full text

Changing Pattern of Organ Donation at a Single Center: Are Potential Brain Dead Donors Being Lost to Donation After Cardiac Death? by Saidi, R. F., Bradley, J., Greer, D., Luskin, R., O’Connor, K., Delmonico, F., Kennealey, P., Pathan, F., Schuetz, C., Elias, N., Ko, D. S. C., Kawai, T., Hertl, M., Cosimi, A. B., Markmann, J. F.

“…Donation after cardiac death (DCD) has proven effective at increasing the availability of organs for transplantation. We performed a retrospective examination…”
Get full text

An Unexpected Counter‐Regulatory Role of IL‐10 in B‐Lymphocyte‐Mediated Transplantation Tolerance by Zhao, G., Moore, D. J., Lee, K. M., Kim, J. I., Duff, P. E., O’Connor, M. R., Hirohashi, T., Lei, J., Yang, M., Markmann, J. F., Deng, S.

“…Monoclonal antibody against the CD45RB protein induces stable transplantation tolerance to multiple types of allograft. We have previously established that…”
Get full text

Immune Exhaustion and Transplantation by Sanchez‐Fueyo, A., Markmann, J. F.

“…Exhaustion of lymphocyte function through chronic exposure to a high load of foreign antigen is well established for chronic viral infection and antitumor…”
Get full text

Early Onset Adenovirus Infection after Simultaneous Kidney–Pancreas Transplant by Varma, M. C., Kushner, Y. B., Ko, D. S., Kawai, T., Martins, P., Kaur, P., Markmann, J. F., Kotton, C. N.

“…Adenoviruses (AdV) are increasingly recognized as important viral pathogens in immunocompromised hosts. The clinical spectrum ranges from asymptomatic viremia…”
Get full text

Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines by Karangwa, S. A., Dutkowski, P., Fontes, P., Friend, P. J., Guarrera, J. V., Markmann, J. F., Mergental, H., Minor, T., Quintini, C., Selzner, M., Uygun, K., Watson, C. J., Porte, R. J.

“…With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor…”
Get full text

Signatures of Tolerance or Immunosuppression? by Markmann, J. F.

“…A new analysis of the peripheral blood lymphocyte transcription signature in spontaneously tolerant kidney recipients corrects for the potentially confounding…”
Get full text

Prophylaxis against hepatitis B recurrence following liver transplantation using combination lamivudine and hepatitis B immune globulin by Markowitz, Jay S., Martin, Paul, Conrad, Andrew J., Markmann, James F., Seu, Philip, Yersiz, Hasan, Goss, John A., Schmidt, Peter, Pakrasi, Anita, Artinian, Lucy, Murray, Natalie G., Imagawa, David K., Holt, Curtis, Goldstein, Leonard I., Stribling, Risë, Busuttil, Ronald W.

“…Patients undergoing liver transplantation for hepatitis B–related liver disease are prone to recurrence. The mainstay of prophylaxis has been passive…”
Get full text

Regulatory T‐Cell Counter‐Regulation by Innate Immunity Is a Barrier to Transplantation Tolerance by Kim, J. I., Lee IV, M. K., Moore, D. J., Sonawane, S. B., Duff, P. E., O’Connor, M. R., Yeh, H., Lian, M. M., Deng, S., Caton, A. J., Markmann, J. F.

“…Innate immune signals foster adaptive immunity through activation of antigen‐presenting cells. Recent in vitro evidence suggests that innate signaling may also…”
Get full text

Prolonged Survival Following Pig‐to‐Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade by Shah, J. A., Patel, M. S., Elias, N., Navarro‐Alvarez, N., Rosales, I., Wilkinson, R. A., Louras, N. J., Hertl, M., Fishman, J. A., Colvin, R. B., Cosimi, A. B., Markmann, J. F., Sachs, D. H., Vagefi, P. A.

“…Since the first attempt of pig‐to‐primate liver xenotransplantation (LXT) in 1968, survival has been limited. We evaluated a model utilizing…”
Get full text

Financial Issues Constraining the Use of Pancreata Recovered for Islet Transplantation: A White Paper by Markmann, J. F., Kaufman, D. B., Ricordi, C., Schwab, P. M., Stock, P. G.

“…Islet transplantation is a very promising therapy for select patients with type 1 diabetes. Continued clinical investigation is required to define the…”
Get full text

Isolated Pancreatic Islet Transplantation: A Coming of Age by Markmann, J.F.

“…Based on improved outcomes of pancreatic islet transplantation as well as success in the recently completed phase III licensure trials conducted by the CIT,…”
Get full text

Role of Patient Factors and Practice Patterns in Determining Access to Liver Waitlist by Adler, J. T., Dong, N., Markmann, J. F., Schoenfeld, D., Yeh, H.

“…Geographic variability in access to care is a persistent challenge in transplantation. Little is known about how patients with end‐stage liver disease are…”
Get full text

Orthotopic liver transplantation for hepatitis C : Outcome, effect of immunosuppression, and causes of retransplantation during an 8-year single-center experience by GHOBRIAL, R. M, FARMER, D. G, GOLDSTEIN, L. I, MARTIN, P, BUSUTTIL, R. W, MCDONALD, R. J, GABER, A. O, HOWARD, R. J, HENDERSON, J. M, BAQUERIZO, A, COLQUHOUN, S, ROSEN, H. R, YERSIZ, H, MARKMANN, J. F, DRAZAN, K. E, HOLT, C, IMAGAWA, D

“…To determine the outcome of orthotopic liver transplantation (OLT) for end-stage liver disease caused by hepatitis C virus (HCV). HCV has become the leading…”
Get full text

Regulatory B Cell‐Dependent Islet Transplant Tolerance Is Also Natural Killer Cell Dependent by Schuetz, C., Lee, K. M., Scott, R., Kojima, L., Washburn, L., Liu, L., Liu, W.‐H., Tector, H., Lei, J., Yeh, H., Kim, J. I., Markmann, J. F.

“…Immunologic tolerance to solid organ and islet cell grafts has been achieved in various rodent models by using antibodies directed at CD45RB and Tim‐1. We have…”
Get full text