Search Results - "Markham, Peter M."

Innervation Patterns May Limit Response to Endovascular Renal Denervation by Tzafriri, Abraham R., PhD, Mahfoud, Felix, MD, Keating, John H., DVM, DACVP, Markham, Peter M., MS, Spognardi, Anna, BA, Wong, Gee, BS, HT, Fuimaono, Kristine, BS, Böhm, Michael, MD, Edelman, Elazer R., MD, PhD

“…Abstract Background Renal denervation is a new interventional approach to treat hypertension with variable results. Objectives The purpose of this study was to…”
Get full text

Sex differences in the outcomes of stent implantation in mini-swine model by Kunio, Mie, Wong, Gee, Markham, Peter M, Edelman, Elazer R

“…Sex-related differences have been noted in cardiovascular anatomy, pathophysiology, and treatment responses, yet we continued to drive evaluation of vascular…”
Get full text

Procedural and Anatomical Determinants of Multielectrode Renal Denervation Efficacy: Insights From Preclinical Models by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John H, Spognardi, Anna-Maria, Markham, Peter M, Wong, Gee, Highsmith, Debby, O’Fallon, Patrick, Fuimaono, Kristine, Edelman, Elazer R

“…Radiofrequency renal denervation is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine the…”
Get full text

Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension by Tzafriri, Abraham R, Keating, John H, Markham, Peter M, Spognardi, Anna-Maria, Stanley, James R L, Wong, Gee, Zani, Brett G, Highsmith, Debby, O'Fallon, Patrick, Fuimaono, Kristine, Mahfoud, Felix, Edelman, Elazer R

“…Renal denervation (RDN) is a treatment option for patients with hypertension resistant to conventional therapy. Clinical trials have demonstrated variable…”
Get more information

Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug by Carlyle, Wenda C., McClain, James B., Tzafriri, Abraham R., Bailey, Lynn, Zani, Brett G., Markham, Peter M., Stanley, James R.L., Edelman, Elazer R.

“…Current drug eluting stent (DES) technology is not optimized with regard to the pharmacokinetics of drug delivery. A novel, absorbable-coating…”
Get full text

Evaluation of renal nerve morphological changes and norepinephrine levels following treatment with novel bipolar radiofrequency delivery systems in a porcine model by Cohen-Mazor, Meital, Mathur, Prabodh, Stanley, James R.L, Mendelsohn, Farrell O, Lee, Henry, Baird, Rose, Zani, Brett G, Markham, Peter M, Rocha-Singh, Krishna

“…OBJECTIVE:To evaluate the safety and effectiveness of different bipolar radiofrequency system algorithms in interrupting the renal sympathetic nerves and…”
Get full text

Biocompatibility, bone healing, and safety evaluation in rabbits with an IlluminOss bone stabilization system by McSweeney, Amanda L., Zani, Brett G., Baird, Rose, Stanley, James R. L., Hayward, Alison, Markham, Peter M., Kopia, Gregory A., Edelman, Elazer R., Rabiner, Robert

“…ABSTRACT Bone healing, biocompatibility, and safety employing the IlluminOss System (IS), comprised of an inflatable balloon filled with photopolymerizable…”
Get full text

Evaluation of an intramedullary bone stabilization system using a light-curable monomer in sheep by Zani, Brett G., Baird, Rose, Stanley, James R. L., Markham, Peter M., Wilke, Markus, Zeiter, Stephan, Beck, Aswin, Nehrbass, Dirk, Kopia, Gregory A., Edelman, Elazer R., Rabiner, Robert

“…Percutaneous intramedullary fixation may provide an ideal method for stabilization of bone fractures, while avoiding the need for large tissue dissections…”
Get full text

Particulates from hydrophilic-coated guiding sheaths embolise to the brain by Stanley, James R L, Tzafriri, Abraham R, Regan, Kathryn, LaRochelle, Alan, Wong, Gee, Zani, Brett G, Markham, Peter M, Bailey, Lynn, Spognardi, Anna, Kopia, Gregory A, Edelman, Elazer R

“…We sought to evaluate the incidence of embolic material in porcine brains following vascular interventions using hydrophilic-coated sheaths. A new…”
Get full text

CRT-500.10 Ridaforolimus Eluting Stents with Customizable Diffusion Controlled Release Kinetics and Tissue Uptake by Tzafriri, Abraham R, Markham, Peter M, LaRochelle, Alan W, Spognardi, Anna-Maria, Bailey, Lynn, Cohen, Ilana, Elmalak, Omar, Richter, Yoram, Edelman, Elazer R

Get full text

CRT-712 Preclinical Safety And Efficacy Of A Novel Multielectrode Bipolar/unipolar Over-the-wire Renal Denervation Rf Catheter by Tzafriri, Abraham R, Bailey, Lynn, Keating, John H, Markham, Peter M, Prutchi, David, Edelman, Elazer R

Get full text

Ultra-hydrophilic stent platforms promote early vascular healing and minimise late tissue response: a potential alternative to second-generation drug-eluting stents by Kolandaivelu, Kumaran, Bailey, Lynn, Buzzi, Stefano, Zucker, Arik, Milleret, Vincent, Ziogas, Algirdas, Ehrbar, Martin, Khattab, Ahmed A, Stanley, James R L, Wong, Gee K, Zani, Brett, Markham, Peter M, Tzafriri, Abraham R, Bhatt, Deepak L, Edelman, Elazer R

“…Simple surface modifications can enhance coronary stent performance. Ultra-hydrophilic surface (UHS) treatment of contemporary bare metal stents (BMS) was…”
Get full text

CRT-306 Particulates from Hydrophilic Coated Guiding Sheaths Embolize to the Brain by Stanley, James RL, Regan, Kathryn, LaRochelle, Alan, Zani, Brett G, Markham, Peter M, Bailey, Lynn, Spognardi, Anna, Wong, Gee, Tzafriri, Abraham R, Kopia, Gregory A, Edelman, Elazer R

Get full text

Procedural and anatomical determinants of multi-electrode renal denervation efficacy – insights from preclinical models by Tzafriri, Abraham R., Mahfoud, Felix, Keating, John H., Spognardi, Anna-Maria, Markham, Peter M., Wong, Gee, Highsmith, Debby, O’Fallon, Patrick, Fuimaono, Kristine, Edelman, Elazer R.

“…Radiofrequency renal denervation (RDN) is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine…”
Get full text

Particulates from Hydrophilic-Coated Guiding Sheaths Embolize to the Brain by Stanley, James R.L., Tzafriri, Abraham R., Regan, Kathryn, LaRochelle, Alan, Wong, Gee, Zani, Brett G., Markham, Peter M., Bailey, Lynn, Spognardi, Anna, Kopia, Gregory A., Edelman, Elazer R.

Get full text

Procedural and Anatomical Determinants of Multielectrode Renal Denervation Efficacy by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John H, Spognardi, Anna-Maria, Markham, Peter M, Wong, Gee, Highsmith, Debby, O'Fallon, Patrick, Fuimaono, Kristine, Edelman, Elazer R

“…Radiofrequency renal denervation is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine the…”
Get full text

Methodological Standardization for the Pre-Clinical Evaluation of Renal Sympathetic Denervation by Sakakura, Kenichi, MD, Ladich, Elena, MD, Edelman, Elazer R., MD, Markham, Peter, MS, Stanley, James R.L., DVM, Keating, John, DVM, Kolodgie, Frank D., PhD, Virmani, Renu, MD, Joner, Michael, MD

“…Abstract Transcatheter ablation of renal autonomic nerves is a viable option for the treatment of resistant arterial hypertension; however, structured…”
Get full text

Comparative disposition of 2,3-epoxy-1-propanol (glycidol) in rats following oral and intravenous administration by Nomeir, A A, Silveira, D M, Ferrala, N F, Markham, P M, McComish, M F, Ghanayem, B I, Chadwick, M

“…Glycidol (2,3-epoxy-1-propanol), an industrial chemical, has been shown to be a reproductive toxicant in short-term studies and a carcinogen in rats and mice…”
Get more information

Pharmacokinetics and distribution of a 33P-labeled anti-human immunodeficiency virus oligonucleotide (AR177) after single- and multiple-dose intravenous administration to rats by Wallace, T L, Bazemore, S A, Holm, K, Markham, P M, Shea, J P, Chaudhary, N, Cossum, P A

“…AR177 is a 17-mer oligonucleotide that has anti-human immunodeficiency virus activity in vitro. The disposition of internally labeled 33P-AR177 was studied…”
Get more information

Pulmonary absorption and disposition of [14C]thiophene in rats following nose-only inhalation exposure by Nomeir, A A, Markham, P M, Chadwick, M

“…The absorption, disposition, and metabolism of [14C]thiophene was investigated in rats following nose-only inhalation exposure at 8000 ppm for 1 h. Under these…”
Get more information