Search Results - "Mark S. Johnson"
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PAS domains in bacterial signal transduction
Published in Current opinion in microbiology (01-06-2021)“…[Display omitted] •PAS domains are common sensing, signaling, dimerization, and localization domains.•Sensing versatility derives from a conserved cleft that…”
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A Prospective Investigation of Physical Health Outcomes in Abused and Neglected Children: New Findings From a 30-Year Follow-Up
Published in American journal of public health (1971) (01-06-2012)“…We investigated whether abused and neglected children are at risk for negative physical health outcomes in adulthood. Using a prospective cohort design, we…”
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3
Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation
Published in PloS one (19-09-2019)“…Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor important in diverse biological processes including cell proliferation and survival…”
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Establishing a Secure, Transparent, and Autonomous Blockchain of Custody for Renewable Energy Credits and Carbon Credits
Published in IEEE engineering management review (01-12-2018)“…To facilitate the widespread adoption of clean energy, we must devise practical economic incentives to deploy clean energy assets while reducing barriers to…”
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Two structural motifs within canonical EF-hand calcium-binding domains identify five different classes of calcium buffers and sensors
Published in PloS one (14-10-2014)“…Proteins with EF-hand calcium-binding motifs are essential for many cellular processes, but are also associated with cancer, autism, cardiac arrhythmias, and…”
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Distinctive structural motifs co‐ordinate the catalytic nucleophile and the residues of the oxyanion hole in the alpha/beta‐hydrolase fold enzymes
Published in Protein science (01-02-2019)“…The alpha/beta‐hydrolases (ABH) are among the largest structural families of proteins that are found in nature. Although they vary in their sequence and…”
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Application of biochar and nitrogen influences fluxes of CO2, CH4 and N2O in a forest soil
Published in Journal of environmental management (01-05-2017)“…Nitrogen (N) fertilization of forests for increasing carbon sequestration and wood volume is expected to influence soil greenhouse gas (GHG) emissions,…”
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Structural Catalytic Core of the Members of the Superfamily of Acid Proteases
Published in Molecules (Basel, Switzerland) (01-08-2024)“…The superfamily of acid proteases has two catalytic aspartates for proteolysis of their peptide substrates. Here, we show a minimal structural scaffold, the…”
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The acid-base-nucleophile catalytic triad in ABH-fold enzymes is coordinated by a set of structural elements
Published in PloS one (21-02-2020)“…The alpha/beta-Hydrolases (ABH) are a structural class of proteins that are found widespread in nature and includes enzymes that can catalyze various reactions…”
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10
Hyperspectral and Thermal Sensing of Stomatal Conductance, Transpiration, and Photosynthesis for Soybean and Maize under Drought
Published in Remote sensing (Basel, Switzerland) (01-10-2020)“…During water stress, crops undertake adjustments in functional, structural, and biochemical traits. Hyperspectral data and machine learning techniques (PLS-R)…”
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The undetected loss of aged carbon from boreal mineral soils
Published in Scientific reports (18-03-2021)“…The boreal forest is among the largest terrestrial biomes on earth, storing more carbon (C) than the atmosphere. Due to rapid climatic warming and enhanced…”
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Land‐Atmosphere Coupling Constrains Increases to Potential Evaporation in a Warming Climate: Implications at Local and Global Scales
Published in Earth's future (01-02-2023)“…The magnitude and extent of runoff reduction, drought intensification, and dryland expansion under climate change are unclear and contentious. A primary reason…”
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13
An extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation
Published in Nature communications (14-11-2022)“…The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here, ErbB4 isoforms are used as a model to address…”
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14
Active site opening and closure control translocation of multisubunit RNA polymerase
Published in Nucleic acids research (01-08-2012)“…Multisubunit RNA polymerase (RNAP) is the central information-processing enzyme in all cellular life forms, yet its mechanism of translocation along the DNA…”
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15
Accurate conformation-dependent molecular electrostatic potentials for high-throughput in silico drug discovery
Published in Journal of computational chemistry (01-06-2010)“…The atom-centered partial charges-approximation is commonly used in current molecular modeling tools as a computationally inexpensive alternative to quantum…”
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16
Assessing the Complementary Role of Surface Flux Equilibrium (SFE) Theory and Maximum Entropy Production (MEP) Principle in the Estimation of Actual Evapotranspiration
Published in Journal of advances in modeling earth systems (01-07-2023)“…Although evapotranspiration (ET) from the land is a key variable in Earth system models, the accurate estimation of ET based on physical principles remains…”
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17
Adoption of Body Mass Index Guidelines for Screening and Counseling In Pediatric Practice
Published in Pediatrics (Evanston) (01-02-2010)“…The purpose of this study was to examine pediatrician implementation of BMI and provider interventions for childhood overweight prevention and treatment. Data…”
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Current perspectives on the use of alternative species in human health and ecological hazard assessments
Published in Environmental health perspectives (01-09-2013)“…Traditional animal toxicity tests can be time and resource intensive, thereby limiting the number of chemicals that can be comprehensively tested for potential…”
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SUMOylation regulates nuclear accumulation and signaling activity of the soluble intracellular domain of the ErbB4 receptor tyrosine kinase
Published in The Journal of biological chemistry (01-12-2017)“…Erb-B2 receptor tyrosine kinase 4 (ErbB4) is a kinase that can signal via a proteolytically released intracellular domain (ICD) in addition to classical…”
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CO2 efflux from Amazonian headwater streams represents a significant fate for deep soil respiration
Published in Geophysical research letters (03-09-2008)“…Large Amazonian rivers are known to emit substantial amounts of CO2 to the atmosphere, while the magnitude of CO2 degassing from small streams remains a major…”
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