Search Results - "Mark Collins"

TBK1: a new player in ALS linking autophagy and neuroinflammation by Oakes, James A, Davies, Maria C, Collins, Mark O

“…Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder affecting motor neurons, resulting in progressive muscle weakness and death by…”
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Quantitative Proteomics Reveals the Basis for the Biochemical Specificity of the Cell-Cycle Machinery by Pagliuca, Felicia Walton, Collins, Mark O., Lichawska, Agata, Zegerman, Philip, Choudhary, Jyoti S., Pines, Jonathon

“…Cyclin-dependent kinases comprise the conserved machinery that drives progress through the cell cycle, but how they do this in mammalian cells is still…”
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Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins by Bayés, Alex, Collins, Mark O, Croning, Mike D R, van de Lagemaat, Louie N, Choudhary, Jyoti S, Grant, Seth G N

“…Direct comparison of protein components from human and mouse excitatory synapses is important for determining the suitability of mice as models of human brain…”
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S‐acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion by Woodley, Keith T, Collins, Mark O

“…S‐acylation (palmitoylation) is the only fully reversible lipid modification of proteins; however, little is known about how protein S‐acyltransferases (PATs)…”
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The extracellular matrix supports breast cancer cell growth under amino acid starvation by promoting tyrosine catabolism by Nazemi, Mona, Yanes, Bian, Martinez, Montserrat Llanses, Walker, Heather J, Pham, Khoa, Collins, Mark O, Bard, Frederic, Rainero, Elena

“…Breast tumours are embedded in a collagen I-rich extracellular matrix (ECM) network, where nutrients are scarce due to limited blood flow and elevated tumour…”
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Regulation and function of the palmitoyl‐acyltransferase ZDHHC5 by Woodley, Keith T., Collins, Mark O.

“…Protein palmitoylation (S‐acylation) has emerged as an important player in a range of cellular processes, and as a result, the palmitoyl‐acyltransferase (PAT)…”
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Global, site-specific analysis of neuronal protein S-acylation by Collins, Mark O., Woodley, Keith T., Choudhary, Jyoti S.

“…Protein S-acylation (palmitoylation) is a reversible lipid modification that is an important regulator of dynamic membrane-protein interactions. Proteomic…”
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Analysis of Protein Palmitoylation Reveals a Pervasive Role in Plasmodium Development and Pathogenesis by Jones, Matthew L., Collins, Mark O., Goulding, David, Choudhary, Jyoti S., Rayner, Julian C.

“…Asexual stage Plasmodium falciparum replicates and undergoes a tightly regulated developmental process in human erythrocytes. One mechanism involved in the…”
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FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid-liquid phase separation by Kaizuka, Takeshi, Hirouchi, Taisei, Saneyoshi, Takeo, Shirafuji, Toshihiko, Collins, Mark O, Grant, Seth G N, Hayashi, Yasunori, Takumi, Toru

“…Proteome analyses of the postsynaptic density (PSD), a proteinaceous specialization beneath the postsynaptic membrane of excitatory synapses, have identified…”
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Lateral Tibial Posterior Slope Is Increased in Patients With Early Graft Failure After Anterior Cruciate Ligament Reconstruction by Christensen, Joshua J., Krych, Aaron J., Engasser, William M., Vanhees, Matthias K., Collins, Mark S., Dahm, Diane L.

“…Background: The lateral tibial posterior slope (LTPS) has been reported in multiple studies to correlate with an increased risk for native anterior cruciate…”
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A potential histone-chaperone activity for the MIER1 histone deacetylase complex by Wang, Siyu, Fairall, Louise, Pham, Trong Khoa, Ragan, Timothy J, Vashi, Dipti, Collins, Mark O, Dominguez, Cyril, Schwabe, John W R

“…Abstract Histone deacetylases 1 and 2 (HDAC1/2) serve as the catalytic subunit of six distinct families of nuclear complexes. These complexes repress gene…”
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Evolution of complexity in the zebrafish synapse proteome by Bayés, Àlex, Collins, Mark O., Reig-Viader, Rita, Gou, Gemma, Goulding, David, Izquierdo, Abril, Choudhary, Jyoti S., Emes, Richard D., Grant, Seth G. N.

“…The proteome of human brain synapses is highly complex and is mutated in over 130 diseases. This complexity arose from two whole-genome duplications early in…”
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Characterization of the proteome, diseases and evolution of the human postsynaptic density by Grant, Seth G N, Bayés, Àlex, van de Lagemaat, Louie N, Collins, Mark O, Croning, Mike D R, Whittle, Ian R, Choudhary, Jyoti S

“…We isolated the postsynaptic density from human neocortex (hPSD) and identified 1,461 proteins. hPSD mutations cause 133 neurological and psychiatric diseases…”
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A Plasmodium Calcium-Dependent Protein Kinase Controls Zygote Development and Transmission by Translationally Activating Repressed mRNAs by Sebastian, Sarah, Brochet, Mathieu, Collins, Mark O., Schwach, Frank, Jones, Matthew L., Goulding, David, Rayner, Julian C., Choudhary, Jyoti S., Billker, Oliver

“…Calcium-dependent protein kinases (CDPKs) play key regulatory roles in the life cycle of the malaria parasite, but in many cases their precise molecular…”
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Interferon-induced ISG15 pathway: an ongoing virus–host battle by Zhao, Chen, Collins, Mark N, Hsiang, Tien-Ying, Krug, Robert M

“…Highlights ► ISG15 has antiviral activity and is conjugated to viral proteins during infection. ► Some viral proteins bind ISG15 to counter its antiviral…”
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APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment by Pines, Jonathon, Mansfeld, Jörg, Collin, Philippe, Collins, Mark O, Choudhary, Jyoti S

“…Faithful chromosome segregation during mitosis depends on the spindle assembly checkpoint (SAC), which monitors kinetochore attachment to the mitotic spindle…”
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Radiation therapist perceptions on how artificial intelligence may affect their role and practice by O'Shaughnessey, Julie, Collins, Mark L

“…Introduction The use of artificial intelligence (AI) has increased in medical radiation science, with advanced computing and modelling. Considering radiation…”
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AMPA receptor complex dynamics in time and space by Collins, Mark O

“…Using a comprehensive proteomic approach, Schwenk et al. (2014), in this issue of Neuron, resolve the differential composition of AMPA receptor complexes in…”
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Arthritis Progression on Serial MRIs Following Diagnosis of Medial Meniscal Posterior Horn Root Tear by Krych, Aaron J, Johnson, Nick R, Mohan, Rohith, Hevesi, Mario, Stuart, Michael J, Littrell, Laurel A, Collins, Mark S

“…Medial meniscus posterior root tears (MMPRTs) are a significant source of pain and dysfunction. The purpose of this study was to evaluate changes in the medial…”
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Stem Cells Combined With Platelet-rich Plasma Effectively Treat Corticosteroid-induced Osteonecrosis of the Hip: A Prospective Study by Houdek, Matthew T, Wyles, Cody C, Collins, Mark S, Howe, Benjamin M, Terzic, Andre, Behfar, Atta, Sierra, Rafael J

“…Randomized trials have shown the benefits of injecting bone marrow-derived mesenchymal stem cells (BmMSCs) after standard hip decompression in patients with…”
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