Search Results - "Mark, T M"

IL-10 from Regulatory T Cells Determines Vaccine Efficacy in Murine Leishmania major Infection by Stober, Carmel B, Lange, Uta G, Roberts, Mark T. M, Alcami, Antonio, Blackwell, Jenefer M

“…Leishmaniasis affects 12 million people, but there are no vaccines. Immunological correlates of vaccine efficacy are unclear. Polarized Th1 vs Th2 responses in…”
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LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease by Broekman, Mark M T J, Roelofs, Hennie M J, Hoentjen, Frank, Wiegertjes, Renske, Stoel, Nicole, Joosten, Leo A, de Jong, Dirk J, Wanten, Geert J A

“…Crohn's disease (CD) is a chronic inflammatory disease in which cytokines play a pivotal role in the induction and maintenance of inflammation. Innate cytokine…”
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Real-time TaqMan PCR for rapid detection and typing of genes encoding CTX-M extended-spectrum β-lactamases by BIRKETT, Christopher I, LUDLAM, Hugo A, WOODFORD, Neil, BROWN, Derek F. J, BROWN, Nicholas M, ROBERTS, Mark T. M, MILNER, Nicola, CURRAN, Martin D

“…The prevalence of CTX-M-producing members of the Enterobacteriaceae is increasing worldwide. A novel, multiplex, real-time TaqMan PCR assay to detect and type…”
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Risk Factors for Rectal Stump Cancer in Inflammatory Bowel Disease by Lutgens, Maurice W. M D, van Oijen, Martijn G H, Vleggaar, Frank P, Siersema, Peter D, Broekman, Mark M. T J, Oldenburg, Bas

“…BACKGROUND:Patients with long-standing colitis carry an increased risk of colorectal cancer and are therefore enrolled in colonoscopic surveillance programs…”
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Allopurinol and 5-aminosalicylic acid influence thiopurine-induced hepatotoxicity in vitro by Broekman, Mark M. T. J., Roelofs, Hennie M. J., Wong, Dennis R., Kerstholt, Mariska, Leijten, Alex, Hoentjen, Frank, Peters, Wilbert H. M., Wanten, Geert J. A., de Jong, Dirk J.

“…Introduction The use of thiopurines is frequently accompanied by hepatotoxicity. Studies on hepatocyte cultures showed a time- and dose-dependent increase of…”
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Interleukin-4 (IL-4) and IL-10 Collude in Vaccine Failure for Novel Exacerbatory Antigens in Murine Leishmania major Infection by ROBERTS, Mark T. M, STOBER, Carmel B, MCKENZIE, Andrew N, BLACKWELL, Jenefer M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Heterologous Priming-Boosting with DNA and Modified Vaccinia Virus Ankara Expressing Tryparedoxin Peroxidase Promotes Long-Term Memory against Leishmania major in Susceptible BALB/c Mice by Stober, Carmel B, Lange, Uta G, Roberts, Mark T.M, Alcami, Antonio, Blackwell, Jenefer M

“…Leishmaniasis affects 12 million people, but there are no vaccines in routine clinical use. Th1 polarizing vaccines that elicit long-term protection are…”
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GST Theta null genotype is associated with an increased risk for ulcerative colitis: a case-control study and meta-analysis of GST Mu and GST Theta polymorphisms in inflammatory bowel disease by Broekman, Mark M T J, Bos, Caro, Te Morsche, René H M, Hoentjen, Frank, Roelofs, Hennie M J, Peters, Wilbert H M, Wanten, Geert J A, de Jong, Dirk J

“…Glutathione S-transferases (GSTs) are important in the detoxification of many compounds, including reactive oxygen species. Polymorphisms in GSTs resulting in…”
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From genome to vaccines for leishmaniasis: Screening 100 novel vaccine candidates against murine Leishmania major infection by Stober, Carmel B., Lange, Uta G., Roberts, Mark T.M., Gilmartin, Brian, Francis, Richard, Almeida, Renata, Peacock, Christopher S., McCann, Sharon, Blackwell, Jenefer M.

“…The genomic sequence of Leishmania major provides a rich source of vaccine candidates. One hundred randomly selected amastigote-expressed genes were screened…”
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Half a Marathon a Day: Excessive Walking in People With Dementia Living in Long-Term Care Facilities by Broekman, Mark M.T.J., van den Biggelaar, Ilse, de Vijlder, Lieke S., Lodema, Caroline, van der Vegte, Yvonne, Groen, Wim G., Sizoo, Eefje M.

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Patterns of progression on first line osimertinib in patients with EGFR mutation-positive advanced non-small cell lung cancer (NSCLC): A Swiss cohort study by Schuler, A, Huser, J, Schmid, S, Schär, S, Scherz, A, Gautschi, O, Mauti, L, von Briel, T, Waibel, C, Wannesson, L, Pankovics, J, Mark, M T, Rothschild, S I, Addeo, A, Janthur, W D, Siano, M, Boos, L, Britschgi, C, Früh, M

“…Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) approved for patients with EGFR mutated non-small…”
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Obtaining control of cell surface functionalizations via Pre-targeting and Supramolecular host guest interactions by Rood, Mark T. M., Spa, Silvia J., Welling, Mick M., ten Hove, Jan Bart, van Willigen, Danny M., Buckle, Tessa, Velders, Aldrik H., van Leeuwen, Fijs W. B.

“…The use of mammalian cells for therapeutic applications is finding its way into modern medicine. However, modification or “training” of cells to make them…”
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More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing by Broekman, Mark M T J, Coenen, Marieke J H, van Marrewijk, Corine J, Wanten, Geert J A, Wong, Dennis R, Verbeek, Andre L M, Klungel, Olaf H, Hooymans, Piet M, Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J J, de Jong, Dirk J

“…There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat…”
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Common single nucleotide polymorphisms in transient receptor potential melastatin type 6 increase the risk for proton pump inhibitor-induced hypomagnesemia: a case–control study by Hess, Mark W, de Baaij, Jeroen H.F, Broekman, Mark M.T.J, Bisseling, Tanya M, Haarhuis, Bertram J.T, Tan, Adriaan C.I.T.L, te Morsche, René H.M, Hoenderop, Joost G.J, Bindels, René J.M, Drenth, Joost P.H

“…OBJECTIVEProton pump inhibitors (PPIs) are effective drugs for the treatment of gastric acid-related disorders. Serious adverse events are rare for PPIs, but…”
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SAKK 17/16 - Lurbinectedin monotherapy in patients with progressive malignant pleural mesothelioma: A multicenter, single-arm phase II trial by Metaxas, Y., Xyrafas, A., Mark, M.T., Pless, M., Frueh, M., Froesch, P.R., Schneider, M., Biaggi Rudolf, C., Grosso, F., von Moos, R.

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Impact of early prophylactic cranial irradiation with hippocampal avoidance on neurocognitive function in patients with limited disease small cell lung cancer: A multicenter phase II trial (SAKK 15/12) by Vees, H., Caparrotti, F., Xyrafas, A., Fuhrer, A.C., Meier, U.R., Mark, M.T., Elicin, O., Aebersold, D.M., Betticher, D.C., Biaggi Rudolf, C., Ribi, K., Finazzi, T., Zwahlen, D.R.

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A randomised phase III trial evaluating the addition of denosumab to standard first-line treatment in advanced NSCLC: The ETOP and EORTC SPLENDOUR trial by Peters, S., Danson, S.J., Hasan, B., Reinmuth, N., Majem, M., Tournoy, K.G., Mark, M.T., Pless, M., Cobo, M., Rodriguez-Abreu, D., Falchero, L., Massutí, B., Coate, L., von Moos, R., Zielinski, C.C., De Maio, E., O’Brien, M., Roschitzki-Voser, H., Dafni, U., Stahel, R.A.

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Patients’ beliefs about medicine are associated with early thiopurine discontinuation in patients with inflammatory bowel diseases by Broekman, Mark M.T.J, Coenen, Marieke J.H, Wanten, Geert J, van Marrewijk, Corine J, Kievit, Wietske, Klungel, Olaf H, Verbeek, André L.M, Wong, Dennis R, Hooymans, Piet M, Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J.J, Bouvy, Marcel L, de Jong, Dirk J

“…BACKGROUNDPatients’ beliefs about medicine may either reflect the necessity for treatment or concerns regarding the treatment. We explored the extent to which…”
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AIDS-associated progressive multifocal leukoencephalopathy : Current management strategies by ROBERTS, Mark T. M

“…Progressive multifocal leukoencephalopathy (PML) is a rare, opportunistic infection of the CNS by the ubiquitous JC virus (JCV). PML is only seen in the…”
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Molecular Basis of Human Cardiac Troponin T Isoforms Expressed in the Developing, Adult, and Failing Heart by Anderson, Page A.W, Greig, Ann, Mark, Trisha M, Malouf, Nadia N, Oakeley, Annette E, Ungerleider, Ross M, Allen, Paul D, Kay, Brian K

“…Cardiac troponin T (cTnT), a protein essential for calcium-regulated myofibrillar ATPase activity, is expressed in the human heart as four isoforms (cTnT1…”
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