Search Results - "Marjomäki, Varpu"

Nanomolar Pyrophosphate Detection in Water and in a Self-Assembled Hydrogel of a Simple Terpyridine-Zn2+ Complex by Bhowmik, Sandip, Ghosh, Biswa Nath, Marjomäki, Varpu, Rissanen, Kari

“…A simple terpyridine-Zn(II) complex is shown to act as an efficient and highly selective fluorescent sensor for pyrophosphate in water at physiological pH. The…”
Get full text

Antiviral Agents From Fungi: Diversity, Mechanisms and Potential Applications by Linnakoski, Riikka, Reshamwala, Dhanik, Veteli, Pyry, Cortina-Escribano, Marta, Vanhanen, Henri, Marjomäki, Varpu

“…Viral infections are amongst the most common diseases affecting people worldwide. New viruses emerge all the time and presently we have limited number of…”
Get full text

A Common Receptor Found for Echoviruses by Laajala, Mira, Marjomäki, Varpu

“…It has remained a puzzle why infants, during the first weeks of life, are especially prone to enterovirus infections. New work (Proc. Natl. Acad. Sci. U. S. A…”
Get full text

Therapeutic targets for enterovirus infections by Laajala, Mira, Reshamwala, Dhanik, Marjomäki, Varpu

“…Enteroviruses are among the most common viruses causing a huge number of acute and chronic infections leading to high economic costs. Novel nontoxic antivirals…”
Get more information

Coxsackie B virus by Marjomäki, Varpu, Flodström-Tullberg, Malin

Get full text

A Novel Open and Infectious Form of Echovirus 1 by Myllynen, Mira, Kazmertsuk, Artur, Marjomäki, Varpu

“…One of the hallmarks of enterovirus genome delivery is the formation of an uncoating intermediate particle. Based on previous studies of mostly heated…”
Get full text

Modification of face masks with zeolite imidazolate framework-8: A tool for hindering the spread of COVID-19 infection by Givirovskaia, Daria, Givirovskiy, Georgy, Haapakoski, Marjo, Hokkanen, Sanna, Ruuskanen, Vesa, Salo, Satu, Marjomäki, Varpu, Ahola, Jero, Repo, Eveliina

“…The worldwide spread of the SARS-CoV-2 virus has continued to accelerate, putting a considerable burden on public health, safety, and the global economy…”
Get full text

Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation by Ruokolainen, Visa, Domanska, Aušra, Laajala, Mira, Pelliccia, Maria, Butcher, Sarah J, Marjomäki, Varpu

“…There is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time…”
Get full text

SAR Analysis of Novel Coxsackie virus A9 Capsid Binders by Tammaro, Chiara, Plavec, Zlatka, Myllymäki, Laura, Mitchell, Cristopher, Consalvi, Sara, Biava, Mariangela, Ciogli, Alessia, Domanska, Aušra, Leppilampi, Valtteri, Buckner, Cienna, Manetto, Simone, Sciò, Pietro, Coluccia, Antonio, Laajala, Mira, Dondio, Giulio M., Bigogno, Chiara, Marjomäki, Varpu, Butcher, Sarah J., Poce, Giovanna

“…Enterovirus infections are common in humans, yet there are no approved antiviral treatments. In this study we concentrated on inhibition of one of the…”
Get full text

Infectious Entry Pathway of Enterovirus B Species by Marjomäki, Varpu, Turkki, Paula, Huttunen, Moona

“…Enterovirus B species (EV-B) are responsible for a vast number of mild and serious acute infections. They are also suspected of remaining in the body, where…”
Get full text

Enzyme-assisted extraction of anthocyanins and other phenolic compounds from blackcurrant (Ribes nigrum L.) press cake: From processing to bioactivities by Granato, Daniel, Fidelis, Marina, Haapakoski, Marjo, dos Santos Lima, Amanda, Viil, Janeli, Hellström, Jarkko, Rätsep, Reelika, Kaldmäe, Hedi, Bleive, Uko, Azevedo, Luciana, Marjomäki, Varpu, Zharkovsky, Alexander, Pap, Nora

“…[Display omitted] •Blackcurrant press cake (BPC) was extracted with cellulase/beta-glucanase/pectinase.•Enzyme-assisted extraction increased the recovery to…”
Get full text

From the forest to the plate – Hemicelluloses, galactoglucomannan, glucuronoxylan, and phenolic-rich extracts from unconventional sources as functional food ingredients by Granato, Daniel, Reshamwala, Dhanik, Korpinen, Risto, Azevedo, Luciana, Vieira do Carmo, Mariana Araújo, Cruz, Thiago Mendanha, Marques, Mariza Boscacci, Wen, Mingchun, Zhang, Liang, Marjomäki, Varpu, Kilpeläinen, Petri

“…[Display omitted] •Forest industry side-streams showed antiviral, antioxidant and antidiabetic potential.•Both wood hemicelluloses and bark polyphenols…”
Get full text

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months by Pelliccia, Maria, Andreozzi, Patrizia, Paulose, Jayson, D’Alicarnasso, Marco, Cagno, Valeria, Donalisio, Manuela, Civra, Andrea, Broeckel, Rebecca M., Haese, Nicole, Jacob Silva, Paulo, Carney, Randy P., Marjomäki, Varpu, Streblow, Daniel N., Lembo, David, Stellacci, Francesco, Vitelli, Vincenzo, Krol, Silke

“…Up to 80% of the cost of vaccination programmes is due to the cold chain problem (that is, keeping vaccines cold). Inexpensive, biocompatible additives to slow…”
Get full text

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells by Ifie, Eseoghene, Russell, Mark A., Dhayal, Shalinee, Leete, Pia, Sebastiani, Guido, Nigi, Laura, Dotta, Francesco, Marjomäki, Varpu, Eizirik, Decio L., Morgan, Noel G., Richardson, Sarah J.

“…Aims/hypothesis The Coxsackie and adenovirus receptor (CAR) is a transmembrane cell-adhesion protein that serves as an entry receptor for enteroviruses and may…”
Get full text

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins by Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu

“…We report that several viruses from the human enterovirus group B cause massive vimentin rearrangements during lytic infection. Comprehensive studies suggested…”
Get full text

Early Entry Events in Echovirus 30 Infection by Vandesande, Helena, Laajala, Mira, Kantoluoto, Tino, Ruokolainen, Visa, Lindberg, A Michael, Marjomäki, Varpu

“…Echovirus 30 (E30), a member of the enterovirus B species, is a major cause of viral meningitis, targeting children and adults alike. While it is a frequently…”
Get full text

Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release by Domanska, Aušra, Plavec, Zlatka, Ruokolainen, Visa, Löflund, Benita, Marjomäki, Varpu, Butcher, Sarah J

“…Coxsackievirus A9 (CVA9), an enterovirus, is a common cause of pediatric aseptic meningitis and neonatal sepsis. During cell entry, enterovirus capsids undergo…”
Get full text

Field-Grown and In Vitro Propagated Round-Leaved Sundew ( Drosera rotundifolia L.) Show Differences in Metabolic Profiles and Biological Activities by Tienaho, Jenni, Reshamwala, Dhanik, Karonen, Maarit, Silvan, Niko, Korpela, Leila, Marjomäki, Varpu, Sarjala, Tytti

“…L. is a carnivorous plant used in traditional medicine for its therapeutic properties. Because of its small size, its collection in nature is laborious and…”
Get full text

Impact of HDAC inhibitors on macrophage polarization to enhance innate immunity against infections by Bhat, Mohammad Faizan, Srdanović, Sonja, Sundberg, Lotta-Riina, Einarsdóttir, Helga Kristín, Marjomäki, Varpu, Dekker, Frank J.

“…[Display omitted] Innate immunity plays an important role in host defense against pathogenic infections. It involves macrophage polarization into either the…”
Get full text

Antiviral functionalization of cellulose using tannic acid and tannin-rich extracts by Haapakoski, Marjo, Emelianov, Aleksei, Reshamwala, Dhanik, Laajala, Mira, Tienaho, Jenni, Kilpeläinen, Petri, Liimatainen, Jaana, Jyske, Tuula, Pettersson, Mika, Marjomäki, Varpu

“…Due to seasonally appearing viruses and several outbreaks and present pandemic, we are surrounded by viruses in our everyday life. In order to reduce viral…”
Get full text