Search Results - "Mariotti, Francesca"

Managing institutional diversity and structural holes: Network configurations for recombinant innovation by Mariotti, Francesca, Haider, Sajjad

“…•This study uncovers which network configurations are responsible for recombinant innovation and how firms develop network management capabilities.•These…”
Get full text

PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects by Munari, Enrico, Mariotti, Francesca R, Quatrini, Linda, Bertoglio, Pietro, Tumino, Nicola, Vacca, Paola, Eccher, Albino, Ciompi, Francesco, Brunelli, Matteo, Martignoni, Guido, Bogina, Giuseppe, Moretta, Lorenzo

“…Immune evasion is a key strategy adopted by tumor cells to escape the immune system while promoting their survival and metastatic spreading. Indeed, several…”
Get full text

IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC by Mariotti, Francesca R., Supino, Domenico, Landolina, Nadine, Garlanda, Cecilia, Mantovani, Alberto, Moretta, Lorenzo, Maggi, Enrico

“…Interleukin-1 receptor family members (ILRs) and Toll-Like Receptors (TLRs) play pivotal role in immunity and inflammation and are expressed by most cell types…”
Get full text

PD-L1 Assays 22C3 and SP263 are Not Interchangeable in Non–Small Cell Lung Cancer When Considering Clinically Relevant Cutoffs: An Interclone Evaluation by Differently Trained Pathologists by Munari, Enrico, Rossi, Giulio, Zamboni, Giuseppe, Lunardi, Gianluigi, Marconi, Marcella, Sommaggio, Marco, Netto, George J, Hoque, Mohammad O, Brunelli, Matteo, Martignoni, Guido, Haffner, Michael C, Moretta, Francesca, Pegoraro, Maria C, Cavazza, Alberto, Samogin, Giuseppina, Furlan, Vanna, Mariotti, Francesca R, Vacca, Paola, Moretta, Lorenzo, Bogina, Giuseppe

“…Pembrolizumab is the only programmed cell death 1/programmed death-ligand 1 inhibitor for treatment of patients with non–small cell lung cancer, with a…”
Get full text

PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression by Mariotti, Francesca R, Petrini, Stefania, Ingegnere, Tiziano, Tumino, Nicola, Besi, Francesca, Scordamaglia, Francesca, Munari, Enrico, Pesce, Silvia, Marcenaro, Emanuela, Moretta, Alessandro, Vacca, Paola, Moretta, Lorenzo

“…Under physiological conditions, PD-1/PD-L1 interactions regulate unwanted over-reactions of immune cells and contribute to maintain peripheral tolerance…”
Get full text

Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis by Corrado, Mauro, Mariotti, Francesca R, Trapani, Laura, Taraborrelli, Lucia, Nazio, Francesca, Cianfanelli, Valentina, Soriano, Maria Eugenia, Schrepfer, Emilie, Cecconi, Francesco, Scorrano, Luca, Campello, Silvia

“…Mitochondrial dynamics and functionality are linked to the autophagic degradative pathway under several stress conditions. However, the interplay between…”
Get full text

Comparison of three validated PD-L1 immunohistochemical assays in urothelial carcinoma of the bladder: interchangeability and issues related to patient selection by Munari, Enrico, Querzoli, Giulia, Brunelli, Matteo, Marconi, Marcella, Sommaggio, Marco, Cocchi, Marco A., Martignoni, Guido, Netto, George J., Caliò, Anna, Quatrini, Linda, Mariotti, Francesca R., Luchini, Claudio, Girolami, Ilaria, Eccher, Albino, Segala, Diego, Ciompi, Francesco, Zamboni, Giuseppe, Moretta, Lorenzo, Bogina, Giuseppe

“…Different programmed cell death-ligand 1 (PD-L1) assays and scoring algorithms are being used in the evaluation of PD-L1 expression for the selection of…”
Get full text

H3 k36 methylation helps determine the timing of cdc45 association with replication origins by Pryde, Fiona, Jain, Devanshi, Kerr, Alastair, Curley, Rebecca, Mariotti, Francesca Romana, Vogelauer, Maria

“…Replication origins fire at different times during S-phase. Such timing is determined by the chromosomal context, which includes the activity of nearby genes,…”
Get full text

Hemophagocytic Lymphohistiocytosis and Miliary Tuberculosis in an Apparently Immunocompetent Patient: A Case Report by Ducci, Filippo, Mariotti, Francesca, Mencarini, Jessica, Fabbri, Claudio, Manunta, Alessandra Francesca, Messeri, Daniela, Parronchi, Paola, Blanc, Pierluigi, Bartoloni, Alessandro

“…Hemophagocytic lymphohistiocytosis (HLH) is a serious haematologic condition that can be related to various diseases, including tuberculosis (TB). The patient…”
Get full text

Effects of Partial Substitution of Conventional Protein Sources with Duckweed ( Lemna minor ) Meal in the Feeding of Rainbow Trout ( Oncorhynchus mykiss ) on Growth Performances and the Quality Product by Fiordelmondo, Elisa, Ceschin, Simona, Magi, Gian Enrico, Mariotti, Francesca, Iaffaldano, Nicolaia, Galosi, Livio, Roncarati, Alessandra

“…Duckweed (Lemna minor) meal was included in the formulation of three experimental feeds (L1, L2, L3) for rainbow trout at 10%, 20%, 28% of the protein source,…”
Get full text

Immunohistochemical Expression of p62 in Feline Mammary Carcinoma and Non-Neoplastic Mammary Tissue by Magi, Gian Enrico, Mariotti, Francesca, Pallotta, Lorenzo, Di Cerbo, Alessandro, Venanzi, Franco Maria

“…The p62 protein, also called sequestosome 1 (SQSTM1), is a ubiquitin-binding scaffold protein. In human oncology, although the interest in the function of this…”
Get full text

Effect of a Guar Meal Protein Concentrate in Replacement of Conventional Feedstuffs on Productive Performances and Gut Health of Rainbow Trout (Oncorhynchus mykiss) by Roncarati, Alessandra, Galosi, Livio, Di Cerbo, Alessandro, Quagliardi, Martina, Marchetti, Francesco, Fiordelmondo, Elisa, Mariotti, Francesca, Magi, Gian Enrico

“…A trial was performed to investigate the effect of a proprietary guar protein concentrate, as a partial replacement of conventional protein sources, on the…”
Get full text

Dropout in cognitive behavioral treatment in adults living with overweight and obesity: a systematic review by Neri, Lenycia de Cassya Lopes, Mariotti, Francesca, Guglielmetti, Monica, Fiorini, Simona, Tagliabue, Anna, Ferraris, Cinzia

“…Obesity is a chronic, complex, and multifactorial disease resulting from the interaction of genetic, environmental, and behavioral factors. It is characterized…”
Get full text

Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions by Mariotti, Francesca Romana, Quatrini, Linda, Munari, Enrico, Vacca, Paola, Moretta, Lorenzo

“…Innate lymphoid cells (ILCs) belong to a family of immune cells. Recently, ILCs have been classified into five different groups that mirror the function of…”
Get full text

Improvement of the Water Quality in Rainbow Trout Farming by Means of the Feeding Type and Management over 10 Years (2009–2019) by Fiordelmondo, Elisa, Magi, Gian Enrico, Mariotti, Francesca, Bakiu, Rigers, Roncarati, Alessandra

“…Background: In Europe, rainbow trout is one of the main fresh water fish farmed in a constantly developing environment that requires innovative studies to…”
Get full text

Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing by Ingegnere, Tiziano, Mariotti, Francesca Romana, Pelosi, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Tumino, Nicola, Besi, Francesca, Cantoni, Claudia, Locatelli, Franco, Vacca, Paola, Moretta, Lorenzo

“…CAR-NK cells may represent a valuable tool, complementary to CAR-T cells, in adoptive immunotherapy of leukemia and solid tumors. However, gene transfer to…”
Get full text

Does TLS Exist in Canine Mammary Gland Tumours? Preliminary Results in Simple Carcinomas by Giambrone, Giada, Di Giorgio, Stefania, Vullo, Cecilia, Marino, Gabriele, Puleio, Roberto, Mariotti, Francesca, Mazzullo, Giuseppe, Sfacteria, Alessandra

“…Neoplastic progression is influenced by the expression of tumour antigens that activate an anti-tumour immune response. Human medical studies show that this…”
Get full text

Increased Expression of Toll-Like Receptor 4 in Skin of Dogs with Discoid Lupus Erythematous (DLE) by Di Cerbo, Alessandro, Giusti, Sara, Mariotti, Francesca, Spaterna, Andrea, Rossi, Giacomo, Magi, Gian Enrico

“…Discoid lupus erythematous (DLE) is a common autoimmune skin disorder of dogs where keratinocytes play a pivotal role both in the innate and adaptive immune…”
Get full text

Latent Tuberculosis Infection and COVID-19: Analysis of a Cohort of Patients from Careggi University Hospital (Florence, Italy) by Mariotti, Francesca, Sponchiado, Francesco, Lagi, Filippo, Moroni, Chiara, Paggi, Riccardo, Kiros, Seble Tekle, Miele, Vittorio, Bartoloni, Alessandro, Mencarini, Jessica

“…Data regarding the relationship between coronavirus disease (COVID-19) and active or latent tuberculosis (TB) are discordant. We conducted a retrospective…”
Get full text

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer by Sivori, Simona, Della Chiesa, Mariella, Carlomagno, Simona, Quatrini, Linda, Munari, Enrico, Vacca, Paola, Tumino, Nicola, Mariotti, Francesca Romana, Mingari, Maria Cristina, Pende, Daniela, Moretta, Lorenzo

“…The highly destructive mechanisms by which the immune system faces microbial infections is under the control of a series of inhibitory receptors. While most of…”
Get full text