Search Results - "Mario González, John"
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Extensible membrane nanotubules mediate attachment of Trypanosoma cruzi epimastigotes under flow
Published in PloS one (22-03-2023)“…Trypanosoma cruzi is the etiological agent of Chagas disease, an important cause of infectious chronic myocardiopathy in Latin America. The life cycle of the…”
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2
Low frequency of circulating CD8+ T stem cell memory cells in chronic chagasic patients with severe forms of the disease
Published in PLoS neglected tropical diseases (01-01-2015)“…CD8+ T cells have been shown to play a crucial role in Trypanosoma cruzi infection. Memory CD8+ T cells can be categorised based on their distinct…”
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Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients
Published in PLoS neglected tropical diseases (01-05-2018)“…Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular…”
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4
Cross-reactive humoral and CD4 + T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population
Published in Frontiers in immunology (27-07-2023)“…The SARS CoV-2 antibody and CD4 T cell responses induced by natural infection and/or vaccination decline over time and cross-recognize other viral variants at…”
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Effectiveness and adherence to closed face shields in the prevention of COVID-19 transmission: a non-inferiority randomized controlled trial in a middle-income setting (COVPROSHIELD)
Published in Current controlled trials in cardiovascular medicine (20-08-2022)“…The use of respiratory devices can mitigate the spread of diseases such as COVID-19 in community settings. We aimed to determine the effectiveness of closed…”
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CD8+ T Cell Response Quality Is Related to Parasite Control in an Animal Model of Single and Mixed Chronic Trypanosoma cruzi Infections
Published in Frontiers in cellular and infection microbiology (12-10-2021)“…Chagas disease (ChD) is a chronic infection caused by Trypanosoma cruzi . This highly diverse intracellular parasite is classified into seven genotypes or…”
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Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi
Published in PLoS neglected tropical diseases (09-06-2017)“…Congenital T. cruzi infections involve multiple factors in which complex interactions between the parasite and the immune system of pregnant women play…”
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Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients
Published in PloS one (14-03-2016)“…TcTLE is a nonamer peptide from Trypanosoma cruzi KMP-11 protein that is conserved among different parasite strains and that is presented by different HLA-A…”
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Prediction of SARS-CoV-2 infection with a Symptoms-Based model to aid public health decision making in Latin America and other low and middle income settings
Published in Preventive medicine reports (01-06-2022)“…•Early non-pharmacological interventions are necessary limit the spread of COVID-19.•In low to middle-income countries, there are limited resources to face the…”
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10
Characterising the KMP-11 and HSP-70 recombinant antigens' humoral immune response profile in chagasic patients
Published in BMC infectious diseases (25-11-2009)“…Antigen specificity and IgG subclass could be significant in the natural history of Chagas' disease. The relationship between the different stages of human…”
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11
Chagasic patients are able to respond against a viral antigen from influenza virus
Published in BMC infectious diseases (24-08-2012)“…Trypanosoma cruzi, the etiological agent of Chagas' disease, is an obligate intracellular parasite which induces a CD8+ T cell immune response with secretion…”
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12
An Animal Model of Acute and Chronic Chagas Disease With the Reticulotropic Y Strain of Trypanosoma cruzi That Depicts the Multifunctionality and Dysfunctionality of T Cells
Published in Frontiers in immunology (26-04-2019)“…Chagas disease (ChD), a complex and persistent parasitosis caused by , represents a natural model of chronic infection, in which some people exhibit cardiac or…”
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Corrigendum: Cross-reactive humoral and CD4+ T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population
Published in Frontiers in immunology (16-08-2023)Get full text
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14
In reply to: CD4+CD8+ Double-positive T lymphocytes: Pitfalls
Published in Turkish journal of haematology (01-01-2020)“…It was with great interest that we read the recent reply to our published article. Although the effects of nicotine on the immune response have been described…”
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15
Double-positive T Lymphocytes Do Not Vary in Different Age Groups in Colombian Blood Donors
Published in Turkish journal of haematology (01-01-2020)“…We read with interest the letter of Gonzalez-Mancera et al. [1] regarding the percentages and absolute numbers of doublepositive T cells (DPTs) in the…”
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Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein
Published in Peptides (New York, N.Y. : 1980) (01-04-2016)“…•Residues 3, 6 and 7 of TcTLE (TLEEFSAKL) peptide are critical for binding affinity.•Amino acids at positions 3, 6 and 7 of TcTLE have limited effect on…”
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IV Congreso Internacional de Aplicaciones en Citometría de flujo: presente y futuro del análisis celular
Published in Biomédica (28-08-2012)Get full text
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18
Mammalian cellular culture models of Trypanosoma cruzi infection: a review of the published literature
Published in Parasite (Paris) (2014)“…Cellular culture infection with Trypanosoma cruzi is a tool used to dissect the biological mechanisms behind Chagas disease as well as to screen potential…”
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A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi
Published in Memórias do Instituto Oswaldo Cruz (01-04-2013)“…Astrocytes play a vital role in neuronal protection, homeostasis, vascular interchange and the local immune response. Some viruses and parasites can cross the…”
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20
Extensible membrane nanotubules mediate attachment of Trypanosoma cruzi epimastigotes under flow
Published in PloS one (22-03-2023)“…Trypanosoma cruzi is the etiological agent of Chagas disease, an important cause of infectious chronic myocardiopathy in Latin America. The life cycle of the…”
Get full text
Journal Article