Search Results - "Marino, Ramona"
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Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
Published in Nature communications (03-04-2017)“…Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer’s disease (AD) patients and are commonly linked to cognitive and…”
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2
Changes in vitreal protein profile and retina mRNAs in Reeler mice: NGF, IL33 and Müller cell activation
Published in PloS one (27-02-2019)“…A possible link between Nerve Growth Factor (NGF) and Reelin might take place during impaired retinal development occurring in the Reelin deficient mouse model…”
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3
Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice
Published in Molecular neurodegeneration (25-11-2022)“…Abstract Background Recent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the…”
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4
Morphological and biomolecular targets in retina and vitreous from Reelin-deficient mice (Reeler): Potential implications for age-related macular degeneration in Alzheimer’s dementia
Published in Frontiers in aging neuroscience (16-11-2022)“…The neurosensory retina is an outgrowth of the Central Nervous System (CNS), and the eye is considered “a window to the brain.” Reelin glycoprotein is directly…”
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5
Focusing on the interactions between the GABAergic system and neurosteroids in neurodevelopmental disorders
Published in Current pharmaceutical design (01-11-2013)“…Neurosteroids play essential roles in the control of central nervous system functions during physiological and pathological conditions. Increasing evidences…”
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Associations among exposure to methylmercury, reduced Reelin expression, and gender in the cerebellum of developing mice
Published in Neurotoxicology (Park Forest South) (01-12-2014)“…•Reelin expression, male sex and MeHg toxicity interact in the development of anatomical and behavioral autism-like markers.•Autism-like behavioral aspects,…”
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Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival
Published in Neurobiology of disease (01-10-2009)“…Abstract We determined total Purkinje cell (PC) numbers in cerebella of wild-type (+/+) and heterozygous (rl/+) reeler mice of either sex during early…”
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Paradoxical effects of prenatal acetylcholinesterase blockade on neuro-behavioral development and drug-induced stereotypies in reeler mutant mice
Published in Psychopharmacologia (01-08-2006)“…Epidemiological and experimental studies support a link between genetic and epigenetic factors in vulnerability to develop enduring neurobehavioral…”
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9
A Novel 3D Scaffold for Cell Growth to Assess Electroporation Efficacy
Published in Cells (Basel, Switzerland) (01-11-2019)“…Tumor electroporation (EP) refers to the permeabilization of the cell membrane by means of short electric pulses thus allowing the potentiation of…”
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10
Impaired nerve regeneration in reeler mice after peripheral nerve injury
Published in The European journal of neuroscience (01-01-2008)“…Reelin, an extracellular matrix protein, plays an important role in the regulation of neuronal migration and cortical lamination in the developing brain…”
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11
Characterization of NGF, trkA^(NGFR), and p75^(NTR) in Retina of Mice Lacking Reelin Glycoprotein
Published in International Journal of Cell Biology (2014)“…Both Reelin and Nerve Growth Factor (NGF) exert crucial roles in retinal development. Retinogenesis is severely impaired in E-reeler mice, a model of Reelin…”
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12
Characterization of NGF, trkANGFR, and p75NTR in Retina of Mice Lacking Reelin Glycoprotein
Published in International journal of cell biology (01-01-2014)“…Both Reelin and Nerve Growth Factor (NGF) exert crucial roles in retinal development. Retinogenesis is severely impaired in E-reeler mice, a model of Reelin…”
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13
Reelin is transiently expressed in the peripheral nerve during development and is upregulated following nerve crush
Published in Molecular and cellular neuroscience (01-05-2006)“…Reelin is an extracellular matrix protein which is critical for the positioning of migrating post-mitotic neurons and the laminar organization of several brain…”
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Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer’s Disease
Published in Molecular psychiatry (01-05-2024)“…Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental Area (VTA) have been described in Alzheimer’s Disease (AD). During the…”
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15
Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer’s Disease
Published in Progress in neurobiology (01-07-2021)“…•Morphology and autophagic process are impaired in VTA DA neurons of Tg2576 mice.•Tg2576 DA neurons show increased excitability and changes in neuronal…”
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16
The Efficiency of Gene Electrotransfer in Breast-Cancer Cell Lines Cultured on a Novel Collagen-Free 3D Scaffold
Published in Cancers (23-04-2020)“…Gene Electro-Transfer (GET) is a powerful method of DNA delivery with great potential for medical applications. Although GET has been extensively studied in…”
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Perseverative responding and neuroanatomical alterations in adult heterozygous reeler mice are mitigated by neonatal estrogen administration
Published in Psychoneuroendocrinology (01-10-2010)“…Summary According to the “extreme-male brain” theory, elevated fetal testosterone levels may partly explain the skewed sex ratio found in Autism Spectrum…”
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Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders
Published in Molecular neurobiology (01-10-2018)“…Imbalances between excitatory and inhibitory synaptic transmission cause brain network dysfunction and are central to the pathogenesis of neurodevelopmental…”
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NGF Expression in Reelin-Deprived Retinal Cells: A Potential Neuroprotective Effect
Published in Neuromolecular medicine (01-09-2015)“…We recently reported that increased NGF and p75 NTR as well as decreased trkA NGFR characterized the Reelin-deprived ( E - Reeler ) retina, prospecting a…”
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20
Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice
Published in Molecular neurodegeneration (25-11-2022)“…Recent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of…”
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