Search Results - "Marino, Marianna"
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Pleiotropic Outcomes of Glyphosate Exposure: From Organ Damage to Effects on Inflammation, Cancer, Reproduction and Development
Published in International journal of molecular sciences (22-11-2021)“…Glyphosate is widely used worldwide as a potent herbicide. Due to its ubiquitous use, it is detectable in air, water and foodstuffs and can accumulate in human…”
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The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery
Published in International journal of molecular sciences (19-01-2021)“…The endocannabinoid system (ECS) is a lipid cell signaling system involved in the physiology and homeostasis of the brain and peripheral tissues. Synaptic…”
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SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity
Published in Human molecular genetics (01-04-2015)“…Selenoprotein N (SEPN1) is a broadly expressed resident protein of the endoplasmic reticulum (ER) whose loss-of-function inexplicably leads to human muscle…”
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The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
Published in Human molecular genetics (01-09-2010)“…Several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), are characterized by the presence of misfolded proteins, thought to trigger…”
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Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response
Published in Progress in neurobiology (01-05-2012)“…The ubiquitin-proteasome system (UPS) is the major intracellular proteolytic mechanism controlling the degradation of misfolded/abnormal proteins. A common…”
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Correction: The Omega-3 Fatty Acid Eicosapentaenoic Acid Accelerates Disease Progression in a Model of Amyotrophic Lateral Sclerosis
Published in PloS one (11-07-2024)“…[This corrects the article DOI: 10.1371/journal.pone.0061626.]…”
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Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis
Published in Brain (London, England : 1878) (01-11-2013)“…Amyotrophic lateral sclerosis is heterogeneous with high variability in the speed of progression even in cases with a defined genetic cause such as superoxide…”
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Multi-Systemic Alterations by Chronic Exposure to a Low Dose of Bisphenol A in Drinking Water: Effects on Inflammation and NAD+-Dependent Deacetylase Sirtuin1 in Lactating and Weaned Rats
Published in International journal of molecular sciences (07-09-2021)“…Bisphenol A (BPA) is largely used as a monomer in some types of plastics. It accumulates in tissues and fluids and is able to bypass the placental barrier,…”
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PLASTAMINATION: Outcomes on the Central Nervous System and Reproduction
Published in Current neuropharmacology (01-09-2024)“…Environmental exposures to non-biodegradable and biodegradable plastics are unavoidable. Microplastics (MPs) and nanoplastics (NPs) from the manufacturing of…”
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The Other Side of Plastics: Bioplastic-Based Nanoparticles for Drug Delivery Systems in the Brain
Published in Pharmaceutics (01-10-2023)“…Plastics have changed human lives, finding a broad range of applications from packaging to medical devices. However, plastics can degrade into microscopic…”
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The omega-3 fatty acid eicosapentaenoic acid accelerates disease progression in a model of amyotrophic lateral sclerosis
Published in PloS one (19-04-2013)“…Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease characterised by loss of motor neurons that currently has no cure. Omega-3…”
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The interplay between kisspeptin and endocannabinoid systems modulates male hypothalamic and gonadic control of reproduction in vivo
Published in Frontiers in endocrinology (Lausanne) (12-10-2023)“…Introduction Male reproduction is under the control of the hypothalamus–pituitary–gonadal (HPG) axis. The endocannabinoid system (ECS) and the kisspeptin…”
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Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis
Published in Human molecular genetics (01-01-2009)“…In familial and sporadic amyotrophic lateral sclerosis (ALS) and in rodent models of the disease, alterations in the ubiquitin-proteasome system (UPS) may be…”
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Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis
Published in PloS one (02-12-2009)“…Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease, and protein aggregation has been proposed as a possible pathogenetic…”
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A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10
Published in PloS one (23-07-2013)“…Oxidative stress and mitochondrial impairment are the main pathogenic mechanisms of Amyotrophic Lateral Sclerosis (ALS), a severe neurodegenerative disease…”
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The Impact of the European Emission Trading Scheme on Multiple Measures of Economic Performance
Published in Environmental & resource economics (01-10-2018)“…The European Emission Trading Scheme (EU ETS) has introduced a price for carbon, thus generating an additional cost for companies that are regulated by the…”
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Electricity (de)regulation and innovation
Published in Research policy (01-04-2019)“…•We study the effect of (de)regulation (NMR) on innovation in the electricity sector.•The reduction of entry barriers has a major role in the decrease of…”
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Additionality or crowding-out? An overall evaluation of public R&D subsidy on private R&D expenditure
Published in Research policy (01-11-2016)“…•This study evaluates whether public R&D subsidy stimulates private R&D investments in France.•We implement a matching analysis combined with…”
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The Volkswagen emissions scandal: Exploring the role of environmental concern and social norms
Published in Journal of environmental economics and management (01-09-2024)“…Nearly a decade after the 2015 emissions scandal, Volkswagen has transitioned from marketing deceptive ‘clean engine cars’ to becoming a major player in the…”
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What makes entrepreneurship counter-cyclical? Evidence from a shutdown of start-up subsidies in Denmark
Published in Entrepreneurship and regional development (19-10-2024)“…This paper examines how the presence of startup subsidies to the unemployed influences the relationship between business cycle and entrepreneurial activity,…”
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