Search Results - "Marino, M.J"

Activation of the 5-HT6 receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus by West, P.J, Marcy, V.R, Marino, M.J, Schaffhauser, H

“…Abstract The 5-HT6 receptor is predominantly expressed in the CNS and has been implicated in the regulation of cognitive function. Antagonists of the 5-HT6…”
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Paediatric burns patients: Reasons for admission at a tertiary centre by Marino, M.J, Kimble, R.M, Stockton, K.A

“…Highlights • The reasons for admission to a tertiary burns centre in children with a burns injury was determined. • A majority (45%) were admitted for…”
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Validation of a suite of ERP and QEEG biomarkers in a pre-competitive, industry-led study in subjects with schizophrenia and healthy volunteers by Cecchi, M., Adachi, M., Basile, A., Buhl, D.L., Chadchankar, H., Christensen, S., Christian, E., Doherty, J., Fadem, K.C., Farley, B., Forman, M.S., Honda, S., Johannesen, J., Kinon, B.J., Klamer, D., Marino, M.J., Missling, C., O'Donnell, P., Piser, T., Puryear, C.B., Quirk, M.C., Rotte, M., Sanchez, C., Smith, D.G., Uslaner, J.M., Javitt, D.C., Keefe, R.S.E., Mathalon, D., Potter, W.Z., Walling, D.P., Ereshefsky, L.

“…Complexity and lack of standardization have mostly limited the use of event-related potentials (ERPs) and quantitative EEG (QEEG) biomarkers in drug…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents by Hutson, P H, Finger, E N, Magliaro, B C, Smith, S M, Converso, A, Sanderson, P E, Mullins, D, Hyde, L A, Eschle, B K, Turnbull, Z, Sloan, H, Guzzi, M, Zhang, X, Wang, A, Rindgen, D, Mazzola, R, Vivian, J A, Eddins, D, Uslaner, J M, Bednar, R, Gambone, C, Le-Mair, W, Marino, M J, Sachs, N, Xu, G, Parmentier-Batteur, S

“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Activation of the 5-HT 6 receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus by West, P.J., Marcy, V.R., Marino, M.J., Schaffhauser, H.

“…The 5-HT 6 receptor is predominantly expressed in the CNS and has been implicated in the regulation of cognitive function. Antagonists of the 5-HT 6 receptor…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3 S,4 S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2 H-pyran-4-yl)-1,5-dihydro-4 H-pyrazolo[3,4- d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents by Hutson, P.H., Finger, E.N., Magliaro, B.C., Smith, S.M., Converso, A., Sanderson, P.E., Mullins, D., Hyde, L.A., Eschle, B.K., Turnbull, Z., Sloan, H., Guzzi, M., Zhang, X., Wang, A., Rindgen, D., Mazzola, R., Vivian, J.A., Eddins, D., Uslaner, J.M., Bednar, R., Gambone, C., Le-Mair, W., Marino, M.J., Sachs, N., Xu, G., Parmentier-Batteur, S.

“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Haloperidol-induced alteration in the physiological actions of group I mGlus in the subthalamic nucleus and the substantia nigra pars reticulata by Marino, M.J., Awad-Granko, H., Ciombor, K.J., Conn, P.J.

“…Excitatory glutamatergic inputs to the subthalamic nucleus (STN), and subthalamic afferents to the substantia nigra pars reticulata (SNr) are believed to play…”
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endorphin modulates a mechanoreceptor channel in the protozoan Stentor by Marino, M.J., Wood, D.C.

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