Search Results - "Marini, Robert"
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Genomic Landscape and Mutational Signatures of Deafness-Associated Genes
Published in American journal of human genetics (04-10-2018)“…The classification of genetic variants represents a major challenge in the post-genome era by virtue of their extraordinary number and the complexities…”
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2
Assessing variants of uncertain significance implicated in hearing loss using a comprehensive deafness proteome
Published in Human genetics (01-06-2023)“…Hearing loss is the leading sensory deficit, affecting ~ 5% of the population. It exhibits remarkable heterogeneity across 223 genes with 6328 pathogenic…”
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3
Nanoscale Bupivacaine Formulations To Enhance the Duration and Safety of Intravenous Regional Anesthesia
Published in ACS nano (22-01-2019)“…Intravenous regional anesthesia (IVRA; Bier block) is commonly used to anesthetize an extremity for surgery. Limitations of the procedure include pain from the…”
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4
In vivo Engineering of Organs: The Bone Bioreactor
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2005)“…Treatment of large defects requires the harvest of fresh living bone from the iliac crest. Harvest of this limited supply of bone is accompanied by extreme…”
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Helicobacter suis and Helicobacter pylori infection in a colony of research macaques: characterization and clinical correlates
Published in Journal of medical microbiology (01-03-2021)“…( type 1) commonly infects nonhuman primates but its clinical importance is in question. To characterize infection in a colony of rhesus macaques ( ) used in…”
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In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model
Published in Biomaterials (01-09-2006)“…We studied the efficacy of an in situ cross-linked hyaluronic acid hydrogel (HAX) in preventing post-surgical peritoneal adhesions, using a rabbit sidewall…”
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7
Structural Insights into Hearing Loss Genetics from Polarizable Protein Repacking
Published in Biophysical journal (06-08-2019)“…Hearing loss is associated with ∼8100 mutations in 152 genes, and within the coding regions of these genes are over 60,000 missense variants. The majority of…”
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Plasmid-Mediated Quinolone Resistance in Shigella flexneri Isolated From Macaques
Published in Frontiers in microbiology (05-03-2018)“…Non-human primates (NHPs) for biomedical research are commonly infected with spp. that can cause acute dysentery or chronic episodic diarrhea. These animals…”
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Cytotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor (CNF) colonize laboratory macaques
Published in Gut pathogens (06-12-2017)“…Many strains are considered to be a component of the normal flora found in the human and animal intestinal tracts. While most strains are commensal, some…”
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10
Accuracy of cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm to identify sites of origin of cardiac electrical activation
Published in Journal of interventional cardiac electrophysiology (01-09-2020)“…We have developed a system that could potentially be used to identify the site of origin of ventricular tachycardia (VT) and to guide a catheter to that site…”
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11
Estimation of changes in instantaneous aortic blood flow by the analysis of arterial blood pressure
Published in Journal of applied physiology (1985) (01-06-2012)“…The purpose of this study was to introduce and validate a new algorithm to estimate instantaneous aortic blood flow (ABF) by mathematical analysis of arterial…”
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12
Corynebacterium ulcerans in ferrets
Published in Emerging infectious diseases (01-01-2014)Get full text
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13
Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta)
Published in Comparative medicine (01-04-2017)“…Metal alloys are frequently used as implant materials in veterinary medicine. Recent studies suggest that many alloys induce both local and systemic…”
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14
Spontaneous Cholelithiasis in a Squirrel Monkey (Saimiri sciureus)
Published in Comparative medicine (01-02-2016)“…A mature female squirrel monkey was noted during routine semiannual examinations to have moderate progressive weight loss. Serum chemistry panels revealed…”
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Gastric Helicobacter species as a cause of feline gastric lymphoma: A viable hypothesis
Published in Veterinary immunology and immunopathology (15-05-2008)“…Gastric Helicobacter spp. are associated with chronic inflammation and neoplastic transformation in humans as well as domestic and laboratory species. The…”
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17 β-estradiol suppresses Helicobacter pylori-induced gastric pathology in male hypergastrinemic INS-GAS mice
Published in Carcinogenesis (New York) (01-08-2011)“…Helicobacter pylori-associated gastric cancer is male predominant and animal studies suggest that sex hormones influence gastric carcinogenesis. We…”
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17β-Estradiol suppresses Helicobacter pylori-induced gastric pathology in male hypergastrinemic INS-GAS mice
Published in Carcinogenesis (New York) (01-08-2011)“…Helicobacter pylori-associated gastric cancer is male predominant and animal studies suggest that sex hormones influence gastric carcinogenesis. We…”
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Protective role of 17β-estradiol against the development of Helicobacter pylori-induced gastric cancer in INS-GAS mice
Published in Carcinogenesis (New York) (01-12-2007)“…The incidence of gastric cancer is higher in men than women. Epidemiological studies suggest that female hormones reduce gastric cancer risk. We examined the…”
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19
Three-dimensional conductive constructs for nerve regeneration
Published in Journal of biomedical materials research. Part A (01-11-2009)“…The unique electrochemical properties of conductive polymers can be utilized to form stand‐alone polymeric tubes and arrays of tubes that are suitable for…”
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Characterization of Corynebacterium species in macaques
Published in Journal of medical microbiology (01-10-2012)“…Bacteria of the genus Corynebacterium are important primary and opportunistic pathogens. Many are zoonotic agents. In this report, phenotypic (API Coryne…”
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