Search Results - "Marinho, H. Susana"

Hydrogen peroxide sensing, signaling and regulation of transcription factors by Marinho, H Susana, Real, Carla, Cyrne, Luísa, Soares, Helena, Antunes, Fernando

“…The regulatory mechanisms by which hydrogen peroxide (H2O2) modulates the activity of transcription factors in bacteria (OxyR and PerR), lower eukaryotes…”
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Sphingolipid hydroxylation in mammals, yeast and plants – An integrated view by Marquês, Joaquim Trigo, Marinho, H. Susana, de Almeida, Rodrigo F.M.

“…This review is focused on sphingolipid backbone hydroxylation, a small but widespread structural feature with profound impact on membrane biophysical…”
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Tubulin Post-Translational Modifications: The Elusive Roles of Acetylation by Carmona, Bruno, Marinho, H Susana, Matos, Catarina Lopes, Nolasco, Sofia, Soares, Helena

“…Microtubules (MTs), dynamic polymers of α/β-tubulin heterodimers found in all eukaryotes, are involved in cytoplasm spatial organization, intracellular…”
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Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment by Ferreira-Silva, Margarida, Faria-Silva, Catarina, Carvalheiro, Manuela C, Simões, Sandra, Marinho, H Susana, Marcelino, Paulo, Campos, Maria Celeste, Metselaar, Josbert M, Fernandes, Eduarda, Baptista, Pedro V, Fernandes, Alexandra R, Corvo, Maria Luísa

“…Ischemia and reperfusion injury (IRI) is a common complication caused by inflammation and oxidative stress resulting from liver surgery. Current therapeutic…”
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Decrease of H2O2 Plasma Membrane Permeability during Adaptation to H2O2 in Saccharomyces cerevisiae by Branco, Miguel R., Marinho, H. Susana, Cyrne, Luisa, Antunes, Fernando

“…Contrary to what is widely believed, recent published results show that H2O2 does not freely diffuse across biomembranes. The fast removal of H2O2 by…”
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New long circulating magnetoliposomes as contrast agents for detection of ischemia–reperfusion injuries by MRI by Martins, M. Bárbara A.F., PhD, Corvo, M. Luísa, PhD, Marcelino, Paulo, MD, PhD, Marinho, H. Susana, PhD, Feio, Gabriel, PhD, Carvalho, Alexandra, PhD

“…Abstract New long circulating magnetoliposomes coated with polyethylene glycol (PEG), and loaded with PEG-coated 10 nm superparamagnetic iron oxide…”
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Yeast Sphingolipid-Enriched Domains and Membrane Compartments in the Absence of Mannosyldiinositolphosphorylceramide by Bento-Oliveira, Andreia, Santos, Filipa C, Marquês, Joaquim Trigo, Paulo, Pedro M R, Korte, Thomas, Herrmann, Andreas, Marinho, H Susana, de Almeida, Rodrigo F M

“…The relevance of mannosyldiinositolphosphorylceramide [M(IP) C] synthesis, the terminal complex sphingolipid class in the yeast , for the lateral organization…”
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Liquid-Ordered Phase Formation by Mammalian and Yeast Sterols: A Common Feature With Organizational Differences by Khmelinskaia, Alena, Marquês, Joaquim M. T., Bastos, André E. P., Antunes, Catarina A. C., Bento-Oliveira, Andreia, Scolari, Silvia, Lobo, Gerson M. da S., Malhó, Rui, Herrmann, Andreas, Marinho, H. Susana, de Almeida, Rodrigo F. M.

“…Here, biophysical properties of membranes enriched in three metabolically related sterols are analyzed both in vitro and in vivo . Unlike cholesterol and…”
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H2O2 delivery to cells: steady-state versus bolus addition by Marinho, H Susana, Cyrne, Luísa, Cadenas, Enrique, Antunes, Fernando

“…Hydrogen peroxide (H2O2) is a ubiquitous biological molecule whose wide range of biological functions depends on its concentration. In this chapter, we compare…”
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The cellular steady-state of H2O2: latency concepts and gradients by Marinho, H Susana, Cyrne, Luísa, Cadenas, Enrique, Antunes, Fernando

“…Hydrogen peroxide (H2O2) is able to diffuse across biomembranes but, when cells are exposed to external H2O2, the fast consumption of H2O2 inside the cells due…”
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The plasma membrane-enriched fraction proteome response during adaptation to hydrogen peroxide in Saccharomyces cerevisiae by Pedroso, Nuno, Gomes-Alves, Patrícia, Marinho, H Susana, Brito, Verônica B, Boada, Cristina, Antunes, Fernando, Herrero, Enrique, Penque, Deborah, Cyrne, Luísa

“…In Saccharomyces cerevisiae, adaptation to hydrogen peroxide (H₂O₂) decreases plasma membrane permeability to H₂O₂, changes its lipid composition and…”
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A quantitative study of the cell-type specific modulation of c-Rel by hydrogen peroxide and TNF-α by Oliveira-Marques, Virgínia, Silva, Teresa, Cunha, Filipa, Covas, Gonçalo, Marinho, H Susana, Antunes, Fernando, Cyrne, Luísa

“…Hydrogen peroxide (H2O2) at moderate steady-state concentrations synergizes with TNF-α, leading to increased nuclear levels of NF-κB p65 subunit and to a…”
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Antagonist G-targeted liposomes for improved delivery of anticancer drugs in small cell lung carcinoma by Carvalheiro, Manuela, Ferreira-Silva, Margarida, Holovanchuk, Denys, Marinho, H. Susana, Moreira, João Nuno, Soares, Helena, Corvo, M. Luisa, Cruz, Maria Eugénia M.

“…[Display omitted] Ligand-mediated targeted liposomes have the potential to increase therapeutic efficacy of anticancer drugs. This work aimed to evaluate the…”
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Regulation of the inositol transporter Itr1p by hydrogen peroxide in Saccharomyces cerevisiae by Santos, Tomás, Marinho, H. Susana, Cyrne, Luisa

“…Myo -inositol is a precursor of several membrane phospholipids and sphingolipids and plays a key role in gene regulation in Saccharomyces cerevisiae ( S…”
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Gel Domains in the Plasma Membrane of Saccharomyces cerevisiae: HIGHLY ORDERED, ERGOSTEROL-FREE, AND SPHINGOLIPID-ENRICHED LIPID RAFTS by Aresta-Branco, Francisco, Cordeiro, André M, Marinho, H. Susana, Cyrne, Luísa, Antunes, Fernando, de Almeida, Rodrigo F.M

“…The plasma membrane of Saccharomyces cerevisiae was studied using the probes trans-parinaric acid and diphenylhexatriene. Diphenylhexatriene anisotropy is a…”
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Therapeutic activity of superoxide dismutase-containing enzymosomes on rat liver ischaemia-reperfusion injury followed by magnetic resonance microscopy by Marcelino, Paulo, Marinho, H. Susana, Campos, Maria Celeste, Neves, Ana Rita, Real, Carla, Fontes, Filipa S., Carvalho, Alexandra, Feio, Gabriel, Martins, M. Bárbara F., Corvo, M. Luísa

“…Liver ischaemia-reperfusion injury (IRI) may occur during hepatic surgery and is unavoidable in liver transplantation. Superoxide dismutase enzymosomes…”
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Superoxide Dismutase Enzymosomes: Carrier Capacity Optimization, in Vivo Behaviour and Therapeutic Activity by Corvo, M. Luísa, Marinho, H. Susana, Marcelino, Paulo, Lopes, Rui M., Vale, Carlos A., Marques, Claúdia R., Martins, Luísa C.D., Laverman, Peter, Storm, Gert, Martins, M. Bárbara A.F.

“…Purpose A strategy not usually used to improve carrier-mediated delivery of therapeutic enzymes is the attachment of the enzymes to the outer surface of…”
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Formation and Properties of Membrane-Ordered Domains by Phytoceramide: Role of Sphingoid Base Hydroxylation by Marquês, Joaquim T, Cordeiro, André M, Viana, Ana S, Herrmann, Andreas, Marinho, H. Susana, de Almeida, Rodrigo F. M

“…Phytoceramide is the backbone of major sphingolipids in fungi and plants and is essential in several tissues of animal organisms, such as human skin. Its…”
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Reorganization of plasma membrane lipid domains during conidial germination by Santos, Filipa C., Fernandes, Andreia S., Antunes, Catarina A.C., Moreira, Filipe P., Videira, Arnaldo, Marinho, H. Susana, de Almeida, Rodrigo F.M.

“…Neurospora crassa, a filamentous fungus, in the unicellular conidial stage has ideal features to study sphingolipid (SL)-enriched domains, which are implicated…”
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Activation of Nrf2 by H2O2: de novo synthesis versus nuclear translocation by Covas, Gonçalo, Marinho, H Susana, Cyrne, Luísa, Antunes, Fernando

“…The most common mechanism described for the activation of the transcription factor Nrf2 is based on the inhibition of its degradation in the cytosol followed…”
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