Search Results - "Marinho, Fábio V."

Bacillus Calmette-Guérin-Trained Macrophages Elicit a Protective Inflammatory Response against the Pathogenic Bacteria Brucella abortus by de Araujo, Ana Carolina V S C, de Queiroz, Nina M G P, Marinho, Fábio V, Oliveira, Sergio C

“…The bacillus Calmette-Guérin (BCG) can elicit enhanced innate immune responses against a wide range of infections, known as trained immunity. Brucella abortus…”
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Bacillus Calmette-Guérin immunotherapy induces an efficient antitumor response to control murine melanoma depending on MyD88 signaling by Borges, Vinícius M, Marinho, Fábio V, Caldeira, Christiane V A, de Queiroz, Nina M G P, Oliveira, Sergio C

“…Bacillus Calmette-Guérin (BCG) is the first line treatment for bladder cancer and it is also proposed for melanoma immunotherapy. BCG modulates the tumor…”
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The endoplasmic reticulum stress sensor IRE1α modulates macrophage metabolic function during Brucella abortus infection by Guimarães, Erika S, Gomes, Marco Túlio R, Sanches, Rodrigo C O, Matteucci, Kely Catarine, Marinho, Fábio V, Oliveira, Sergio C

“…Endoplasmic reticulum (ER) stress plays a major role in several inflammatory disorders. ER stress induces the unfolded protein response (UPR), a conserved…”
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The use of gold nanorods as a new vaccine platform against schistosomiasis by Assis, Natan R.G., Caires, Anderson J., Figueiredo, Bárbara C., Morais, Suellen B., Mambelli, Fábio S., Marinho, Fábio V., Ladeira, Luís O., Oliveira, Sergio C.

“…Schistosomiasis is an important parasitic disease affecting >207 million people in 76 countries around the world and causing approximately 250,000 deaths per…”
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Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge by Mambelli, Fábio, Marinho, Fábio V, Andrade, Juvana M, de Araujo, Ana C V S C, Abuna, Rodrigo P F, Fabri, Victor M R, Santos, Bruno P O, da Silva, João S, de Magalhães, Mariana T Q, Homan, E Jane, Leite, Luciana C C, Dias, Greicy B M, Heck, Nicoli, Mendes, Daniel A G B, Mansur, Daniel S, Báfica, André, Oliveira, Sergio C

“…COVID-19 has accounted for more than 6 million deaths worldwide. Bacillus Calmette-Guérin (BCG), the existing tuberculosis vaccine, is known to induce…”
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Galectin‐3 regulates proinflammatory cytokine function and favours Brucella abortus chronic replication in macrophages and mice by Tana, Fernanda L., Guimarães, Erika S., Cerqueira, Daiane M., Campos, Priscila C., Gomes, Marco Túlio R., Marinho, Fábio V., Oliveira, Sergio C.

“…In this study, we provide evidence that galectin‐3 (Gal‐3) plays an important role in Brucella abortus infection. Our results showed increased Gal‐3 expression…”
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Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4 + T Cell Responses by Milillo, M Ayelén, Trotta, Aldana, Serafino, Agustina, Marin Franco, José Luis, Marinho, Fábio V, Alcain, Julieta, Genoula, Melanie, Balboa, Luciana, Oliveira, Sergio Costa, Giambartolomei, Guillermo H, Barrionuevo, Paula

“…, the causative agent of brucellosis, displays many resources to evade T cell responses conducive to persist inside the host. Our laboratory has previously…”
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Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection by Marinho, Fábio V, Fahel, Júlia S, Scanga, Charles A, Gomes, Marco Tulio R, Guimarães, Gabriela, Carvalho, Gabrielle R M, Morales, Stefanny V, Báfica, André, Oliveira, Sergio Costa

“…The Toll-like and IL-1 family receptors play critical roles in innate and adaptive immunity against intracellular pathogens. Although previous data…”
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B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway by Milillo, M Ayelén, Velásquez, Lis N, Trotta, Aldana, Delpino, M Victoria, Marinho, Fábio V, Balboa, Luciana, Vermeulen, Mónica, Espindola, Sonia L, Rodriguez-Rodrigues, Nahuel, Fernández, Gabriela C, Oliveira, Sergio Costa, Giambartolomei, Guillermo H, Barrionuevo, Paula

“…Despite eliciting a potent CD8+ T cell response, Brucella abortus is able to persist and establish a chronic infection inside its host. We have previously…”
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Contribution of intercellular adhesion molecule 1 (ICAM-1) to control Mycobacterium avium infection by de Paula, Rafaella R., Marinho, Fábio V., Fahel, Julia S., Oliveira, Sergio C.

“…Mycobacterium avium is a facultative intracellular opportunistic pathogen especially relevant in cases of people living with AIDS. The aim of this study was to…”
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Current Understanding of Bacillus Calmette-Guérin-Mediated Trained Immunity and Its Perspectives for Controlling Intracellular Infections by de Araujo, Ana Carolina V S C, Mambelli, Fábio, Sanches, Rodrigo O, Marinho, Fábio V, Oliveira, Sergio C

“…The bacillus Calmette-Guérin (BCG) is an attenuated bacterium derived from virulent . It is the only licensed vaccine used for preventing severe forms of…”
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TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display by Molinari, Paula, Crespo, María Inés, Molina, Guido N., Dho, Nicolás D., Marinho, Fábio V., Maletto, Belkys, Leclerc, Claude, Oliveira, Sergio C., Taboga, Oscar, Cebrian, Ignacio, Morón, Gabriel

“…Although the baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, represents an…”
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STING regulates metabolic reprogramming in macrophages via HIF-1α during Brucella infection by Gomes, Marco Tulio R, Guimarães, Erika S, Marinho, Fabio V, Macedo, Isabella, Aguiar, Eric R G R, Barber, Glen N, Moraes-Vieira, Pedro M M, Alves-Filho, José Carlos, Oliveira, Sergio C

“…Macrophages metabolic reprogramming in response to microbial insults is a major determinant of pathogen growth or containment. Here, we reveal a distinct…”
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MyD88-dependent BCG immunotherapy reduces tumor and regulates tumor microenvironment in bladder cancer murine model by de Queiroz, Nina M. G. P., Marinho, Fabio V., de Araujo, Ana Carolina V. S. C., Fahel, Julia S., Oliveira, Sergio C.

“…Bacillus Calmette-Guerin (BCG) is the only FDA approved first line therapy for patients with nonmuscle invasive bladder cancer. The purpose of this study is to…”
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Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection by Marinho, Fabio V, Brito, Camila, de Araujo, Ana Carolina V S C, Oliveira, Sergio C

“…Guanylate-binding proteins (GBPs) are produced in response to pro-inflammatory signals, mainly interferons. The most studied cluster of GBPs in mice is on…”
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The role of the adaptor molecule STING during Schistosoma mansoni infection by Souza, Cláudia, Sanches, Rodrigo C. O., Assis, Natan R. G., Marinho, Fábio V., Mambelli, Fábio S., Morais, Suellen B., Gimenez, Enrico G. T., Guimarães, Erika S., Castro, Tiago B. R., Oliveira, Sergio C.

“…Schistosomiasis is a human parasitic disease responsible for serious consequences for public health, as well as severe socioeconomic impacts in developing…”
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Schistosoma mansoni Antigens Modulate Experimental Allergic Asthma in a Murine Model: a Major Role for CD4⁺ CD25⁺ Foxp3⁺ T Cells Independent of Interleukin-10 by Pacífico, Lucila G.G, Marinho, Fábio A.V, Fonseca, Cristina T, Barsante, Michele M, Pinho, Vanessa, Sales-Junior, Policarpo A, Cardoso, Luciana S, Araújo, Maria Ilma, Carvalho, Edgar M, Cassali, Geovanni D, Teixeira, Mauro M, Oliveira, Sergio C

“…In areas where schistosomiasis is endemic, a negative correlation is observed between atopy and helminth infection, associated with a low prevalence of asthma…”
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Toll-Like Receptor 6 Plays an Important Role in Host Innate Resistance to Brucella abortus Infection in Mice by de Almeida, Leonardo A, Macedo, Gilson C, Marinho, Fábio A V, Gomes, Marco T R, Corsetti, Patrícia P, Silva, Aristóbolo M, Cassataro, Juliana, Giambartolomei, Guillermo H, Oliveira, Sergio C

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection by Marinho, Fabio V., Benmerzoug, Sulayman, Rose, Stephanie , Campos, Priscila C., Marques, João T., Báfica, André, Barber, Glen, Ryffel, Bernhard, Oliveira, Sergio C., Quesniaux, Valerie F.J.

“…Mycobacterium tuberculosis (Mtb) infection remains a major public health concern. The STING (stimulator of interferon genes) pathway contributes to the…”
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JVA, an isoniazid analogue, is a bioactive compound against a clinical isolate of the Mycobacterium avium complex by Fahel, Júlia S., Vieira, Rafael P., Marinho, Fábio V., Santos, Viviane C., de Assis, João Vitor, Corsetti, Patrícia P., Ferreira, Rafaela S., de Almeida, Mauro V., Oliveira, Sergio C.

“…Bacteria belonging to Mycobacterium avium complex are organisms of low pathogenicity that infect immunosuppressed individuals. Infection is treated with an…”
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