Search Results - "Marinho, Aline Diogo"
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In silico study of azithromycin, chloroquine and hydroxychloroquine and their potential mechanisms of action against SARS-CoV-2 infection
Published in International journal of antimicrobial agents (01-09-2020)“…•Azithromycin had better binding affinity scores than hydroxychloroquine and chloroquine.•The best binding affinity scores of azithromycin were ACE2 > CTSL >…”
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2
Mebendazole targets essential proteins in glucose metabolism leading gastric cancer cells to death
Published in Toxicology and applied pharmacology (15-09-2023)“…Gastric cancer (GC) is among the most-diagnosed and deadly malignancies worldwide. Deregulation in cellular bioenergetics is a hallmark of cancer. Based on the…”
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3
Renal Effects Induced by Two Phospholipase A2 (Asp‐49 and Lys‐49) Isolated from Bothropoides pauloensis Snake Venom
Published in The FASEB journal (01-04-2019)“…Acute renal failure (ARF) wich is one of the most serious complications of Bothrops snakebites, is one of the main causes of death and consequences for…”
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Effects of cilostazol, a Phosphodiesterase-3 inhibitor, on kidney function and redox imbalance in acute kidney injury caused by Bothrops alternatus venom
Published in Toxicon (Oxford) (01-12-2022)“…The mechanisms of pathogenesis of acute kidney injury (AKI) in snakebites is multifactorial and involves hemodynamic disturbances, with release of free radical…”
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5
A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice
Published in Journal of proteomics (20-02-2022)“…Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and complex pathophysiological condition. Bothrops leucurus is the main…”
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6
New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders
Published in Dalton transactions : an international journal of inorganic chemistry (25-04-2023)“…Nitrosyl ruthenium complexes are promising platforms for nitric oxide (NO) and nitroxyl (HNO) release, which exert their therapeutic application. In this…”
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Synthesis and potential vasorelaxant effect of a novel ruthenium-based nitro complex
Published in Journal of inorganic biochemistry (01-03-2022)“…This study aimed to investigate the synthesis and potential vasodilator effect of a novel ruthenium complex, cis-[Ru(bpy)2(2-MIM)(NO2)]PF6…”
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Phosphodiesterase-5 inhibitor sildenafil attenuates kidney injury induced by Bothrops alternatus snake venom
Published in Toxicon (Oxford) (30-10-2021)“…Acute kidney injury pathogenesis in envenoming by snakes is multifactorial and involves immunologic reactions, hemodynamic disturbances, and direct…”
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Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 mediates acute kidney injury by oxidative stress and release of inflammatory cytokines
Published in Toxicon (Oxford) (30-01-2021)“…The envenomation caused by the Bothrops pauloensis snake leads to severe local and systemic effects including acute kidney injury. In this study, we…”
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Renal effects of venoms of Mexican coral snakes Micrurus browni and Micrurus laticollaris
Published in Toxicon (Oxford) (15-07-2020)“…The Micrurus snake venoms mainly cause systemic complications, essentially neurotoxicity. Previous studies, however, have described that they are involved in…”
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11
ATIVIDADE ANTIBACTERIANA E MODULATORIA DO α-PINENO ASSOCIADO AO APARELHO DE LUZ LED
Published in Revista UniVap (19-04-2022)“…O uso abusivo de medicamentos e a sua venda indiscriminada são um dos principais fatores para a resistência bacteriana, que é um grave problema à saúde. Os…”
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12
Differences between renal effects of venom from two Bothrops jararaca populations from southeastern and southern Brazil
Published in Toxicon (Oxford) (01-01-2017)“…Components from animal venoms may vary according to the snake's age, gender and region of origin. Recently, we performed a proteomic analysis of Bothrops…”
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Vasorelaxant effect of Alpinia zerumbet's essential oil on rat resistance artery involves blocking of calcium mobilization
Published in Fitoterapia (01-09-2023)“…Alpinia zerumbet is a plant from the Zingiberaceae family, popularly used for hypertension treatment. Several studies have demonstrated Alpinia zerumbet…”
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